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Guanosine 5'-O-(2-thiodiphosphate) trisodium

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-137683A
    Guanosine 5'-O-(2-thiodiphosphate) trisodium

    GDPβS trisodium

    		 Adenylate Cyclase Cardiovascular Disease
    Guanosine 5'-O-(2-thiodiphosphate) (trisodium) (GDPβS (trisodium)) is a non-hydrolyzable derivative of GDP. Guanosine 5'-O-(2-thiodiphosphate) (trisodium) is an inhibitor of adenylyl caclase (AC) (Ki = 600 nM). Guanosine 5'-O-(2-thiodiphosphate) (trisodium) partially activates AC in the absence of GPT in cerebral cortex membranes of rodent models (EC50 = 400 nM). Guanosine 5'-O-(2-thiodiphosphate) (trisodium) prevents the release of norepinephrine-induced nitric oxide in cardiac ventricular myocytes .
    Guanosine 5'-O-(2-thiodiphosphate) trisodium

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