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Guanosine 3',5'-cyclic-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub> monophosphate

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W654000

    Guanosine 3',5'-cyclic-<sup>13sup>C,<sup>15sup>N<sub>2sub> monophosphate

    Isotope-Labeled Compounds Endogenous Metabolite Infection Cardiovascular Disease Inflammation/Immunology
    Cyclic GMP- 13C, 15N2 is 13C and 15N labeled Cyclic GMP (HY-113469). Cyclic GMP (cGMP), an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses .
    Cyclic GMP-13C,15N2

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