Gram-negative bacterium

By Targets:	Antibiotic (7) Bacterial (10) Biochemical Assay Reagents (1) Fatty Acid Synthase (FASN) (1) Fungal (1) Phospholipase (2) Reference Standards (1)
By Research Areas:	Cancer (2) Infection (9) Inflammation/Immunology (3)
Oligonucleotides:	Thickeners (1) Emulsifiers (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W012595A

trans-Benzylideneacetone trans-Benzalacetone	Phospholipase	Inflammation/Immunology
trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant .

HY-101128

Bicyclomycin benzoate 2 Publications Verification FR2054	Bacterial Antibiotic	Infection
Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium.

HY-128780B

SPR206 acetate 1 Publications Verification	Bacterial Antibiotic	Infection
SPR206 acetate is a polymyxin analog with antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. SPR206 acetate has an anti-bacterial infection effect by interacting with the bacterium’s outer membrane. The MIC values of SPR206 acetate against *Pseudomonas aeruginosa* Pa14 and *Acinetobacter baumannii* NCTC13301 are both 0.125 mg/L .

HY-W074648

Antibacterial agent 18	Bacterial	Infection
Antibacterial agent 18 is a multi-arm AIE molecule extracted from patent CN110123801A, compound 23. Antibacterial agent 18 can be used for resisting Gram-positive and Gram-negative bacteria. Antibacterial agent 18 can be conjugated in the cell wall of rigid arm configuration insertion bacterium, and block cell wall turns sugar and turns peptide process, to inhibit or kill bacterium .

HY-110354

UCM05 G28UCM	Fatty Acid Synthase (FASN) Bacterial Antibiotic	Infection Cancer
UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines. UCM05 is a Filamentous temperature-sensitive protein Z (FtsZ) inhibitor and inhibits the growth of the Gram-positive bacterium B. subtilis with MIC values of 100 μM but lack activity on the Gram-negative bacterium E. coli.

HY-162329

Antibacterial agent 195	Bacterial Fungal Antibiotic	Infection Inflammation/Immunology
Antibacterial agent 195 (compound A20), a Matrine (HY-N0164) derivative, is a potent antibiotic. Antibacterial agent 195 shows antibacterial activity against Gram-positive bacterium (MIC_S.aureus=0.021 mg/mL; MIC_P.acnes=0.030 mg/mL), Gram-negative bacterium (MIC_E.coli=0.092 mg/mL; MIC_C.albicans=0.379 mg/mL) and Fungus (MIC=2.806 mg/mL) .

HY-W012595AR

trans-Benzylideneacetone (Standard) trans-Benzalacetone (Standard)	Reference Standards Phospholipase	Inflammation/Immunology
trans-Benzylideneacetone (Standard) is the analytical standard of trans-Benzylideneacetone. This product is intended for research and analytical applications. trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant[1].

HY-N12096

Galbinic acid α-Acetylsalazinic acid	Bacterial	Infection
Galbinic acid (α-Acetylsalazinic acid), a lichen acid, shows antibacterial activities against the Gram-positive bacteria B. cereus, B. subtilis, and S. aureus (MICs=62.5, 62.5, 250 μg/ml, respectively). Galbinic acid inhibits the Gram-negative bacterium E. coli (MIC=125 μg/ml) .

HY-174852

Antibacterial agent 285	Antibiotic Bacterial	Infection
Antibacterial agent 285 (Compound 3) is a cephalosporin antibiotic. Antibacterial agent 285 has significant antibacterial activity against gram-negative bacterium with MICs of 0.125-0.5, 0.125-0.5 and 0.125-2 μg/mL for carbapenem-resistant Acinetobacter baumannii (CRAB), Klebsiella pneumoniae (CRE) and Pseudomonas aeruginosa (CRPA), respectively. Antibacterial agent 285 can be used for bacterial infection research, such as complicated urinary tract infections (cUTI) and kidney infections .

HY-121716

Pelagiomicin A Antibiotic 2088A; LL-14I352α	Bacterial	Cancer
Pelagiomicin A is a novel phenazine antibiotic produced by the marine bacterium Pelagiobacter variabilis. The compound is unstable in water and small alcohols. The absolute structure of its major component, Pelagiomicin A, as well as the properties of minor amounts of other structures, were determined by spectroscopic data and synthesis. Pelagiomicin A is active against both Gram-positive and Gram-negative bacteria and exhibits antitumor activity in vitro and in vivo.

HY-174326

Antibacterial agent 282	Antibiotic Bacterial	Infection
Antibacterial agent 282 (Compound CP7), a seleno-Ciprofloxacin (HY-B0356) derivative, is an Antibacterial agent. Antibacterial agent 282 has significant antibacterial activity against gram-positive bacterium and gram-negative bacterium with MICs of 0.1-1.56 and 0.1-3.13 μg/mL, respectively (MBCs of 0.2-1.56 and 0.39-12.5 μg/mL). Antibacterial agent 282 potently disrupts and prevents biofilms formation of P. aeruginosa. Antibacterial agent 282 shows significant inhibitory activity towards the DNA gyrase from E. coli .

HY-A0103

Xanthan gum	Biochemical Assay Reagents	Others
Xanthan gum is a microbial exopolysaccharide produced by Xanthomonas campestris, a Gram-negative aerobic bacterium that is motile and has a polar flagellum. Xanthan gum has unique rheological and gelling properties, forming viscous solutions at low concentrations and remaining stable over a wide range of pH and temperature. Xanthan gum is widely used in the food and petroleum industries as a food additive, thickener or viscosity enhancer, and stabilizer for various suspensions, emulsions, and foams .

HY-N14354

Ferrocin B	Antibiotic Bacterial	Infection
Ferrocin B is an iron-containing cyclic decapeptide antibiotic found in the bacterium Pseudomonas fluorescens YK-310, exhibiting strong antibacterial activity primarily against Gram-negative bacteria, with particularly potent inhibitory effects on Pseudomonas aeruginosa. In a mouse infection model, Ferrocin B shows a half effective dose (ED₅₀) of 0.593 mg/kg against P. aeruginosa. Ferrocin B holds potential for research in the field of anti-infective therapies .

Cat. No.	Product Name	Type

HY-A0103

Xanthan gum	Biochemical Assay Reagents
Xanthan gum is a microbial exopolysaccharide produced by Xanthomonas campestris, a Gram-negative aerobic bacterium that is motile and has a polar flagellum. Xanthan gum has unique rheological and gelling properties, forming viscous solutions at low concentrations and remaining stable over a wide range of pH and temperature. Xanthan gum is widely used in the food and petroleum industries as a food additive, thickener or viscosity enhancer, and stabilizer for various suspensions, emulsions, and foams .

Xanthan gum

Biochemical Assay Reagents

Xanthan gum is a microbial exopolysaccharide produced by Xanthomonas campestris, a Gram-negative aerobic bacterium that is motile and has a polar flagellum. Xanthan gum has unique rheological and gelling properties, forming viscous solutions at low concentrations and remaining stable over a wide range of pH and temperature. Xanthan gum is widely used in the food and petroleum industries as a food additive, thickener or viscosity enhancer, and stabilizer for various suspensions, emulsions, and foams .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W012595A

trans-Benzylideneacetone trans-Benzalacetone	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Inflammation/Immunology Disease Research Fields	Phospholipase
trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant .

HY-W012595AR

trans-Benzylideneacetone (Standard) trans-Benzalacetone (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Reference Standards Phospholipase
trans-Benzylideneacetone (Standard) is the analytical standard of trans-Benzylideneacetone. This product is intended for research and analytical applications. trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant[1].

HY-N12096

Galbinic acid α-Acetylsalazinic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Phenols Polyphenols	Bacterial
Galbinic acid (α-Acetylsalazinic acid), a lichen acid, shows antibacterial activities against the Gram-positive bacteria B. cereus, B. subtilis, and S. aureus (MICs=62.5, 62.5, 250 μg/ml, respectively). Galbinic acid inhibits the Gram-negative bacterium E. coli (MIC=125 μg/ml) .

HY-121716

Pelagiomicin A Antibiotic 2088A; LL-14I352α	Structural Classification Antibiotics Marine natural products Source classification	Bacterial
Pelagiomicin A is a novel phenazine antibiotic produced by the marine bacterium Pelagiobacter variabilis. The compound is unstable in water and small alcohols. The absolute structure of its major component, Pelagiomicin A, as well as the properties of minor amounts of other structures, were determined by spectroscopic data and synthesis. Pelagiomicin A is active against both Gram-positive and Gram-negative bacteria and exhibits antitumor activity in vitro and in vivo.

HY-N14354

Ferrocin B	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Ferrocin B is an iron-containing cyclic decapeptide antibiotic found in the bacterium Pseudomonas fluorescens YK-310, exhibiting strong antibacterial activity primarily against Gram-negative bacteria, with particularly potent inhibitory effects on Pseudomonas aeruginosa. In a mouse infection model, Ferrocin B shows a half effective dose (ED₅₀) of 0.593 mg/kg against P. aeruginosa. Ferrocin B holds potential for research in the field of anti-infective therapies .

Cat. No.	Product Name		Classification

HY-A0103

Xanthan gum		Emulsifiers Thickeners
Xanthan gum is a microbial exopolysaccharide produced by Xanthomonas campestris, a Gram-negative aerobic bacterium that is motile and has a polar flagellum. Xanthan gum has unique rheological and gelling properties, forming viscous solutions at low concentrations and remaining stable over a wide range of pH and temperature. Xanthan gum is widely used in the food and petroleum industries as a food additive, thickener or viscosity enhancer, and stabilizer for various suspensions, emulsions, and foams .

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