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Results for "

GalNAc derivative

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

4

Biochemical Assay Reagents

1

Peptides

1

Oligonucleotides

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147354
    TriGalNAc CBz

    		LYTACs Cardiovascular Disease
    TriGalNAc CBz is a GalNAc derivative and tri-GalNAc is an asialoglycoprotein receptor (ASGPR) ligand. TriGalNAc CBz can be used for mRNA drug delivery as well as lysosomal targeted chimerism (LYTAC) studies .
    TriGalNAc CBz
  • HY-148118A
    Tri-GalNAc(OAc)3 TFA

    		LYTACs Cancer
    Tri-GalNAc(OAc)3 TFA is a trivalent N-acetylgalactosamine (GalNAc) derivative that can be used to synthesize GalNAc-LYTAC. Tri-GalNAc is a specific ligand targeting the asialoglycoprotein receptor (ASGPR), mediating the endocytosis and transport of cell surface proteins (such as EGFR, HER2) to lysosomes for degradation by lysosomal targeting chimeras (LYTACs). Tri-GalNAc significantly reduces the level of target proteins and inhibits downstream signaling pathways (such as EGFR-mediated Akt and MAPK signals). Tri-GalNAc(OAc)3 TFA can be used for hepatocyte targeting studies, and can degrade carcinogenic membrane proteins and inhibit tumor cell proliferation in liver cancer cell models .
    Tri-GalNAc(OAc)3 TFA
  • HY-148118
    Tri-GalNAc(OAc)3

    		LYTACs Cancer
    Tri-GalNAc(OAc)3is a trivalent N-acetylgalactosamine (GalNAc) derivative that can be used to synthesize GalNAc-LYTAC. Tri-GalNAc is a specific ligand targeting the asialoglycoprotein receptor (ASGPR), mediating the endocytosis and transport of cell surface proteins (such as EGFR, HER2) to lysosomes for degradation by lysosomal targeting chimeras (LYTACs). Tri-GalNAc significantly reduces the level of target proteins and inhibits downstream signaling pathways (such as EGFR-mediated Akt and MAPK signals). Tri-GalNAc(OAc)3can be used for hepatocyte targeting studies, and can degrade carcinogenic membrane proteins and inhibit tumor cell proliferation in liver cancer cell models .
    Tri-GalNAc(OAc)3
  • HY-173247
    GalNAc-NAG37 phosphoramidite

    		Biochemical Assay Reagents Others
    GalNAc-NAG37 phosphoramidite, a N-acetylgalactosamine (GalNAc) derivative, is a ligand of asialoglycoprotein receptor (ASGPR). GalNAc-NAG37 phosphoramidite can be used to synthesize GalNAc-siRNA and can be used for oligonucleotide delivery .
    GalNAc-NAG37 phosphoramidite
  • HY-171289
    Neu5Acα2-6GalNAcα1-4GlcNac

    		Biochemical Assay Reagents Others
    Neu5Acα2-6GalNAcα1-4GlcNac is the derivative of Neu5Acα2-6GalNAcα. Neu5Acα2-6GalNAcα can be used for synthesis of glycopolymer .
    Neu5Acα2-6GalNAcα1-4GlcNac
  • HY-173248
    GalNAc-NAG15 phosphoramidite

    		Biochemical Assay Reagents Others
    GalNAc-NAG-15 phosphoramidite is a phosphoramidite derivative containing N-acetylgalactosamine (GalNAc) part linked to NAG, which can be used for the synthesis of oligonucleotides.
    GalNAc-NAG15 phosphoramidite
  • HY-173246
    GalNAc-NAG25 phosphoramidite

    		Biochemical Assay Reagents Others
    GalNAc-NAG-25 phosphoramidite is a phosphoramidite derivative containing N-acetylgalactosamine (GalNAc) part linked to NAG, which can be used for the synthesis of oligonucleotides.
    GalNAc-NAG25 phosphoramidite
  • HY-W1008621
    GalNAc-THA C6 phosphoramidite

    		Biochemical Assay Reagents Others
    GalNAc-THA C6 phosphoramidite is a phosphoramidite derivative containing N-acetylgalactosamine (GalNAc) part linked to Trishexylamino (THA), which can be used for the synthesis of oligonucleotides.
    GalNAc-THA C6 phosphoramidite
  • HY-104004A
    Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH

    Fmoc-Ser-(GalNAc(Ac)3-beta-D)-OH; Fmoc-Ser[GalNAc(Ac)3-β-D]-OH; Fmoc-Ser(Ac3AcNH-β-Gal)-OH

    		 Amino Acid Derivatives Others
    Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH is a serine derivative .
    Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH
  • HY-171987
    trans-4-Hydroxyprolinol-C10-tri-GalNAc

    		Drug Derivative Others
    trans-4-Hydroxyprolinol-C10-tri-GalNAc (Formula XXIV) is a Tri-GaINAc derivative that can be used for nucleic acid drug coupling .
    trans-4-Hydroxyprolinol-C10-tri-GalNAc

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