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Results for "

GCN1

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS05337
    GCN1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    GCN1 Human Pre-designed siRNA Set A contains three designed siRNAs for GCN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GCN1 Human Pre-designed siRNA Set A
    GCN1 Human Pre-designed siRNA Set A
  • HY-W319647
    GCN2 activator-1

    		Eukaryotic Initiation Factor (eIF) Pyruvate Kinase Inflammation/Immunology
    GCN2 activator-1 (Compound 20) is a GCN2 activator. GCN2 activator-1 binds within the ATP-pocket of GCN2 and activates GCN2 in a GCN1-independent manner. GCN2 activator-1 activates Integrated Stress Response (ISR) in cells. GCN2 activator-1 inhibits PKR with an IC50 of 3.75 µM. GCN2 activator-1 can be used for research of pulmonary veno-occlusive disease (PVOD) [1].
    GCN2 activator-1
  • HY-177569
    NVS1.1

    		Eukaryotic Initiation Factor (eIF) Others
    NVS1.1 is a potent, orally active and brain-penetrant readthrough promoter. NVS1.1 triggers the degradation of eRF1 by activating the ribosome-related quality control pathways (involving GCN1, RNF14, and RNF25), thereby facilitating the reading through of premature termination codons. NVS1.1 can be used for the research of genetic diseases caused by nonsense mutations [1].
    NVS1.1
  • HY-177757
    NVS2.1

    		Eukaryotic Initiation Factor (eIF) Others
    NVS2.1 is a potent, orally active and brain-penetrant readthrough promoter. NVS2.1 triggers the degradation of eRF1 by activating the ribosome-related quality control pathways (involving GCN1, RNF14, and RNF25), thereby facilitating the reading through of premature termination codons. NVS2.1 can be used for the research of genetic diseases caused by nonsense mutations [1].
    NVS2.1

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