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Results for "

Fracture

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

2

Peptides

4

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P3497A
    Fmoc-Cys-Asp10 TFA

    		Amino Acid Derivatives Others
    Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .
    Fmoc-Cys-Asp10 TFA
  • HY-150793
    SY-LB-57

    		TGF-β Receptor Cardiovascular Disease Neurological Disease
    SY-LB-57 is a highly potent bone morphogenetic protein (BMP) receptor signaling agonist. SY-LB-57 can be used in studies of diseases such as fractures and pulmonary arterial hypertension .
    SY-LB-57
  • HY-14839
    Evatanepag
    2 Publications Verification

    CP-533536 free acid

    		 Prostaglandin Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology
    Evatanepag (CP-533536) is a non-prostanoid, potent and selective EP2 receptor agonist. Evatanepag can induce local bone formation in vivo. Evatanepag can be used in the research of fractures, bone defects, asthma .
    Evatanepag
  • HY-N2382
    Polyphyllin H

    		Others Neurological Disease Inflammation/Immunology
    Polyphyllin H has been widely used in traditional Chinese medicinal preparations to treat inflammation, fracture and convulsion .
    Polyphyllin H
  • HY-135585
    LY88074

    		Estrogen Receptor/ERR Endocrinology
    LY88074 (Compound 88074) is a Raloxifene analog lacking the basic side chain. Raloxifene is a selective estrogen receptor modulator, and reduces fracture risk at least in part by improving the mechanical properties of bone in a cell- and estrogen receptor-independent manner .
    LY88074
  • HY-15761
    AZD2858
    Maximum Cited Publications
    7 Publications Verification

    		 GSK-3 Neurological Disease
    AZD2858 is a potent, orally active GSK-3 inhibitor, with IC50s of 0.9 and 5 nM for GSK-3α and GSK-3β, respectively, used in the research of fracture healing.
    AZD2858
  • HY-P3497
    Fmoc-Cys-Asp10

    		Amino Acid Derivatives Others
    Fmoc-Cys-Asp10 is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .
    Fmoc-Cys-Asp10
  • HY-14839A
    Evatanepag sodium

    CP 533536

    		 Prostaglandin Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology
    Evatanepag sodium is a non-prostanoid, potent and selective EP2 receptor agonist. Evatanepag sodium can induce local bone formation in vivo. Evatanepag sodium can be used in the research of fractures, bone defects, asthma .
    Evatanepag sodium
  • HY-N15602
    Isosojagol

    		Glycosidase NO Synthase Inflammation/Immunology
    Isosojagol (Compound 5) is a α-Glucosidase inhibitor with an IC50 of 32.2  μM. Isosojagol can be isolated from the Roots of Dolichos trilobus. Isosojagol has anti-inflammatory activity and inhibits LPS (HY-D1056A1)-induced NO production in RAW264.7 cells. Isosojagol can be used for fracture, soft tissue injuries and rheumatoid arthritis research .
    Isosojagol
  • HY-N15723
    Dipsacus saponin A

    		Others Others
    Dipsacus saponin A is an orally active triterpenoid saponin found in the roots of Dipsacus asper. Dipsacus saponin A promotes bone repair by regulating osteoblast activity and inhibiting osteoclast function. Dipsacus saponin A is promising for research of bone diseases such as fracture healing and osteoporosis .
    Dipsacus saponin A
  • HY-N15719
    Dipsacus saponin R

    		Others Others
    Dipsacus saponin R (Compound 1) is an orally active triterpenoid saponin found in Radix Dipsaci. Dipsacus saponin R promotes bone formation and repair by regulating osteoblast activity or inhibiting osteoclast function. Dipsacus saponin R is promising for research of bone diseases such as osteoporosis and fracture healing .
    Dipsacus saponin R
  • HY-107916
    Thyrotropin
    1 Publications Verification

    TSH; Pretiron

    		 TSH Receptor PKC Apoptosis Metabolic Disease Inflammation/Immunology Endocrinology Cancer
    Thyrotropin (TSH, Pretiron) is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid. Thyrotropin induces transcriptional regulation of TH-gatekeeper genes in tanycytes through the Tshr/Gαq/PKC pathway. Thyrotropin prevents Apoptosis. Thyrotropin has an association of low levels with increased bone remodeling, reduced bone mass and a high fracture risk in mice. Thyrotropin is promising for research of skeletal remodeling, hyperthyroidism .
    Thyrotropin
  • HY-107666
    PHA 568487

    		nAChR Neurological Disease Inflammation/Immunology
    PHA 568487 a selective agonist of alpha-7 nicotinic acetylcholine receptor (α-7 nAchR) .PHA 568487 reduces neuroinflammation and oxidative stress . PHA-568487 has rapid brain penetration .
    PHA 568487
  • HY-129674
    PHA 568487 free base

    		nAChR Neurological Disease
    PHA 568487 free base is a selective alpha 7 nicotinic acetylcholine receptor (α-7 nAchR) agonist. PHA 568487 free base reduces neuroinflammation .
    PHA 568487 free base

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