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Results for "

FLI1

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

2

Recombinant Proteins

3

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-122903
    TK216
    5+ Cited Publications

    		 DNA/RNA Synthesis Cancer
    TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor [1]. TK216 directly binds EWS-FLI1 and inhibits EWS-FLI1 protein interactions. TK216 blocks the binding between EWS-FLI1 and RNA helicase A. TK216 has anticancer activity .
    TK216
  • HY-14507
    YK-4-279
    5+ Cited Publications

    		 DNA/RNA Synthesis Apoptosis Cancer
    YK-4-279 blocks RNA Helicase A (RHA) binding with EWS-FLI1 (oncogenic protein). YK-4-279 induces apoptosis and shows anti-proliferation activities towards various cancer cells. YK-4-279 has a chiral center and it can be separated into two enantiomers. YK-4-279 can be used for the research of cancer [1] .
    YK-4-279
  • HY-RS04977
    FLI1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    FLI1 Human Pre-designed siRNA Set A contains three designed siRNAs for FLI1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    FLI1 Human Pre-designed siRNA Set A
    FLI1 Human Pre-designed siRNA Set A
  • HY-RS18357
    Fli1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Fli1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fli1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Fli1 Mouse Pre-designed siRNA Set A
    Fli1 Mouse Pre-designed siRNA Set A
  • HY-RS24836
    Fli1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Fli1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fli1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Fli1 Rat Pre-designed siRNA Set A
    Fli1 Rat Pre-designed siRNA Set A
  • HY-163325
    Fli-1-IN-1 fumarate

    		DNA/RNA Synthesis Cancer
    Fli-1-IN-1 (compound 21) fumarate is a FLI1 targeting agent that directly binds to and inhibits the EWS-FLI1 protein interaction. EWS-FLI1 can bind to RNA helicase A, and Fli-1-IN-1 fumarate inhibits EWS-FLI1 and has potential anticancer activity [1].
    Fli-1-IN-1 fumarate
  • HY-163325A
    Fli-1-IN-1

    		DNA/RNA Synthesis Cancer
    Fli-1-IN-1 (compound 21) is a FLI1 targeting agent that directly binds to and inhibits the EWS-FLI1 protein interaction. EWS-FLI1 can bind to RNA helicase A, and Fli-1-IN-1 inhibits EWS-FLI1 and has potential anticancer activity [1].
    Fli-1-IN-1
  • HY-173364
    EB-TCIP

    BAK-04-212

    		 BCL6 Cancer
    EB-TCIP (BAK-04-212) is a bivalent molecule comprised of AP1867 (HY-114434) and BI-3812 (HY-111381). EB-TCIP can form a reversible ternary complex between FKBP F36V and BCL6 BTB. EB-TCIP recruits FKBP12 F36V-tagged EWS/FLI1 to DNA sites bound by the transcriptional regulator BCL6, leading to rapid expression of BCL6 target genes (eg: SOCS2 and CXCL11). EWS/FLI1 is a fusion transcription factors in Ewing sarcoma. EB-TCIP can be used for research of deregulated transcription in cancer [1].
    EB-TCIP

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