Search Result

Results for "

FABPs

" in MedChemExpress (MCE) Product Catalog:

By Targets:	FABP (16) Fluorescent Dye (1) FXR (1) Mitochondrial Metabolism (1) Nuclear Hormone Receptor 4A/NR4A (1) PPAR (1) Reference Standards (2) Small Interfering RNA (siRNA) (23)
By Research Areas:	Cancer (2) Cardiovascular Disease (5) Inflammation/Immunology (6) Metabolic Disease (13)
Oligonucleotides:	Rat Pre-designed siRNA Sets (7) Mouse Pre-designed siRNA Sets (7) Human Pre-designed siRNA Sets (9) siRNAs (23)

Inhibitors & Agonists

Peptides

Oligonucleotides

Targets Recommended: FABP

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145990

FABPs ligand 6 1 Publications Verification MF6	FABP	Inflammation/Immunology
FABPs ligand 6 (MF6) is an *FABP5* and *FABP7* inhibitor with K_D values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research .

HY-148665

FABP-IN-2	FABP	Others
FABP-IN-2 is a novel *FABP3* ligand. FABP-IN-2 inhibits FABP3/FABP4 with an IC₅₀ of 1.16 μM and 4.27 μM respectively .

HY-127049

Arachidonic acid-biotin	Fluorescent Dye	Others
Arachidonic acid-Biotin is a biotin-labeled Arachidonic acid (HY-109590) that can be used to detect complexes of arachidonic acid with protein binding partners such as fatty acid binding proteins (FABPs) .

HY-158127

FABP1-IN-1 1 Publications Verification	FABP	Metabolic Disease Inflammation/Immunology
FABP1-IN-1 (44) is a selective *FABP1* inhibitor, with an IC₅₀ of 4.46 μM. FABP1-IN-1 (44) can be used for the research of NASH .

HY-163032

FABP4-IN-3	FABP	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
FABP4-IN-3 (compound C3) is a highly selective *FABP4* inhibitor (FABP4 K_i = 25 ± 3 ^a nM, FABP3 K_i = 15.03 μM) which exhibits a 601-fold selectivity over FABP3. FABP4-IN-3 also shows metabolic stability and potent cellular anti-inflammatory activity, making it promising to get involved in the research of metabolic disease, cardiac dysfunction and inflammation-related disease .

HY-160457

FABP4/5-IN-5	FABP	Metabolic Disease
FABP4/5-IN-5 (compound D9) is a potent inhibitor of *FABP4 and FABP*5,? with the IC₅₀s of 4.68 μM and 10.72 μM, respectively.FABP4/5-IN-5 plays an important role in metabolism disorder like diabetes mellitus .

HY-172883

ABP/PPAR modulator 1	FABP PPAR	Metabolic Disease Inflammation/Immunology
ABP/PPAR modulator 1 is an orally active *FABP* and PPAR multiple modulator (IC₅₀s of 0.65  μM and 1.08  μM for FABP1 and FABP4, EC₅₀s of 9.19  μM, 2.20  μM and 1.58 μM for PPARα, PPARγ and PPARδ). ABP/PPAR modulator 1 has potent anti-metabolic dysfunction-associated steatohepatitis (MASH) activity. ABP/PPAR modulator 1 dose-dependently ameliorates multiple pathological characteristics of fatty liver in WD + Carbon tetrachloride-induced MASH mice model .

HY-149953

FABP4-IN-2	FABP	Inflammation/Immunology
FABP4-IN-2 (Compd 10g) is a selective and orally active *FABP4* inhibitor with the K_i values of 0.51 μM for FABP4, 33.01 μM for FABP3. FABP4-IN-2 can be used in the research of inflammation-related diseases .

HY-160456

FABP4/5-IN-4	FABP	Metabolic Disease
FABP4/5-IN-4 (compound E1) is a potent inhibitor of *FABP4 and FABP5, with the IC₅₀s of 3.78 μM and 5.72 μM, respectively. FABP*4/5-IN-4 plays an important role in metabolism disorder like diabetes mellitus .

HY-161892

FABP4-IN-4	FABP	Metabolic Disease Inflammation/Immunology
FABP4-IN-4 (Compound 30) is an orally active inhibitor for *FABP, with IC₅₀* of 1.18 μM for FABP 1. FABP4-IN-4 improves the glucose tolerance, reduces the level of blood glucose, plasma lipids and hepatic inflammatory factors, attenuates hepatic steatosis, and exhibits anti-inflammatory effects in mouse diet-induced obesity models .

HY-117562

*a-FABP-IN-1*	FABP	Metabolic Disease
a-FABP-IN-1 (Compound 5g) is a potent and selective human adipocyte fatty acid-binding protein (a-FABP) inhibitor with a K_i below 1.0 nM. a-FABP-IN-1 inhibits the pro-inflammatory cytokine production .

HY-101903A

BMS-309403 sodium Maximum Cited Publications 17 Publications Verification	FABP	Cardiovascular Disease Metabolic Disease
BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with K_is of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .

HY-101903

BMS-309403 Maximum Cited Publications 17 Publications Verification	FABP	Cardiovascular Disease Metabolic Disease
BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with K_is of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .

HY-RS23414

Fabp3 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fabp3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp3 Rat Pre-designed siRNA Set A Fabp3 Rat Pre-designed siRNA Set A

HY-RS04659

FABP3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FABP3 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FABP3 Human Pre-designed siRNA Set A FABP3 Human Pre-designed siRNA Set A

HY-RS23039

Fabp5 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fabp5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp5 Rat Pre-designed siRNA Set A Fabp5 Rat Pre-designed siRNA Set A

HY-RS23056

Fabp4 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fabp4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp4 Rat Pre-designed siRNA Set A Fabp4 Rat Pre-designed siRNA Set A

HY-RS04662

FABP6 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FABP6 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FABP6 Human Pre-designed siRNA Set A FABP6 Human Pre-designed siRNA Set A

HY-RS04664

FABP9 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FABP9 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FABP9 Human Pre-designed siRNA Set A FABP9 Human Pre-designed siRNA Set A

HY-RS18516

Fabp6 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fabp6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp6 Mouse Pre-designed siRNA Set A Fabp6 Mouse Pre-designed siRNA Set A

HY-RS17252

Fabp1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fabp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp1 Mouse Pre-designed siRNA Set A Fabp1 Mouse Pre-designed siRNA Set A

HY-RS16605

Fabp5 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fabp5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp5 Mouse Pre-designed siRNA Set A Fabp5 Mouse Pre-designed siRNA Set A

HY-RS24377

Fabp7 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fabp7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp7 Rat Pre-designed siRNA Set A Fabp7 Rat Pre-designed siRNA Set A

HY-RS04661

FABP5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FABP5 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FABP5 Human Pre-designed siRNA Set A FABP5 Human Pre-designed siRNA Set A

HY-RS17908

Fabp7 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fabp7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp7 Mouse Pre-designed siRNA Set A Fabp7 Mouse Pre-designed siRNA Set A

HY-RS24998

Fabp6 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp6 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fabp6 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp6 Rat Pre-designed siRNA Set A Fabp6 Rat Pre-designed siRNA Set A

HY-RS04657

FABP12 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FABP12 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FABP12 Human Pre-designed siRNA Set A FABP12 Human Pre-designed siRNA Set A

HY-RS16621

Fabp4 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fabp4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp4 Mouse Pre-designed siRNA Set A Fabp4 Mouse Pre-designed siRNA Set A

HY-RS04663

FABP7 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FABP7 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FABP7 Human Pre-designed siRNA Set A FABP7 Human Pre-designed siRNA Set A

HY-RS23706

Fabp1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fabp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp1 Rat Pre-designed siRNA Set A Fabp1 Rat Pre-designed siRNA Set A

HY-RS18276

Fabp2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fabp2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp2 Mouse Pre-designed siRNA Set A Fabp2 Mouse Pre-designed siRNA Set A

HY-RS24754

Fabp2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fabp2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp2 Rat Pre-designed siRNA Set A Fabp2 Rat Pre-designed siRNA Set A

HY-RS16971

Fabp3 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fabp3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fabp3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fabp3 Mouse Pre-designed siRNA Set A Fabp3 Mouse Pre-designed siRNA Set A

HY-RS04660

FABP4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FABP4 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FABP4 Human Pre-designed siRNA Set A FABP4 Human Pre-designed siRNA Set A

HY-RS04658

FABP2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FABP2 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FABP2 Human Pre-designed siRNA Set A FABP2 Human Pre-designed siRNA Set A

HY-RS04656

FABP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FABP1 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FABP1 Human Pre-designed siRNA Set A FABP1 Human Pre-designed siRNA Set A

HY-161702

RO6806051	FABP	Metabolic Disease
RO6806051 (compound12) is a potent dual fatty acid binding protein 4 and 5 (FABP4 and FABP5) inhibitor with good selectivity and absorption, distribution, metabolism and excretion (eADME) properties .

HY-101903R

BMS-309403 (Standard)	Reference Standards FABP	Cardiovascular Disease Metabolic Disease
BMS-309403 (Standard) is the analytical standard of BMS-309403. This product is intended for research and analytical applications. BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .

HY-101903AR

BMS-309403 sodium (Standard)	Reference Standards FABP	Cardiovascular Disease Metabolic Disease
BMS-309403 (sodium) (Standard) is the analytical standard of BMS-309403 (sodium). This product is intended for research and analytical applications. BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .

HY-149831

ZLY28	FXR	Metabolic Disease
ZLY28 is the first-in-class intestinal restricted and orally active FXR and *FABP1* dual modulator. ZLY28 also is a novel anti-NASH agent. ZLY28 can be used for the research of nonalcoholic steatohepatitis (NASH) .

HY-P4115

CooP	FABP	Cancer
CooP is a linear glioblastoma-targeting nonapeptide. CooP binds to the mammary-derived growth inhibitor/fatty acid binding protein 3 (FABP3) in the glioblastoma cells and its associated vasculature. CooP is used for the targeted delivery of chemotherapy and different nanoparticles .

HY-P10873

ST-CY14	Nuclear Hormone Receptor 4A/NR4A Mitochondrial Metabolism	Cancer
ST-CY14 is an inhibitor for Nur77-PPARγ interaction with an EC₅₀ of 3.15 μM, that binds to Nur77 (K_d=32 nM), blocks Nur77 from being ubiquitinated and degraded by PPARγ, reduces fatty acid uptake and mitochondrial respiration, and inhibits the transcription of CD36 and FABP4. ST-CY14 inhibits the proliferation and migration of cancer cell MCF7 and MDA-MB-231. ST-CY14 inhibits tumor growth and bone metastasis in mouse models .

Cat. No.	Product Name	Target	Research Area

HY-P4115

CooP	FABP	Cancer
CooP is a linear glioblastoma-targeting nonapeptide. CooP binds to the mammary-derived growth inhibitor/fatty acid binding protein 3 (FABP3) in the glioblastoma cells and its associated vasculature. CooP is used for the targeted delivery of chemotherapy and different nanoparticles .

HY-P10873

ST-CY14	Nuclear Hormone Receptor 4A/NR4A Mitochondrial Metabolism	Cancer
ST-CY14 is an inhibitor for Nur77-PPARγ interaction with an EC₅₀ of 3.15 μM, that binds to Nur77 (K_d=32 nM), blocks Nur77 from being ubiquitinated and degraded by PPARγ, reduces fatty acid uptake and mitochondrial respiration, and inhibits the transcription of CD36 and FABP4. ST-CY14 inhibits the proliferation and migration of cancer cell MCF7 and MDA-MB-231. ST-CY14 inhibits tumor growth and bone metastasis in mouse models .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: