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Results for "

Ecdysteroids

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

12

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2548
    Turkesterone

    		Others Cardiovascular Disease
    Turkesterone is a potent ecdysteroid. Turkesterone acts as an ecdysteroid receptor (EcR) agonist in some insect systems .
    Turkesterone
  • HY-128030
    Makisterone A

    		Others Endocrinology
    Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera .
    Makisterone A
  • HY-N1534
    Ponasterone A

    25-Deoxyecdysterone

    		 Others Others
    Ponasterone A (25-Deoxyecdysterone), an ecdysteroid, has strong affinity for the ecdysone receptor. Ponasterone A is a potent regulator of gene expression in cells and transgenic animals, enabling reporter genes to be turned on and off rapidly .
    Ponasterone A
  • HY-113890
    Halofenozide

    RH-0345

    		 Insecticide Others
    Halofenozide (RH-0345) is an ecdysteroid agonist. RH-0345 belongs to a new group of insect growth regulators (IGRs) with a benzoylhydrazine structure that mimic the action of the natural insect molting hormone 20-hydroxyecdysone .
    Halofenozide
  • HY-N6979
    Crustecdysone
    5+ Cited Publications

    20-Hydroxyecdysone

    		 Caspase Autophagy Endogenous Metabolite Cardiovascular Disease
    Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .
    Crustecdysone
  • HY-N2548R
    Turkesterone (Standard)

    		Others Cardiovascular Disease
    Turkesterone (Standard) is the analytical standard of Turkesterone. This product is intended for research and analytical applications. Turkesterone is a potent ecdysteroid. Turkesterone acts as an ecdysteroid receptor (EcR) agonist in some insect systems .
    Turkesterone (Standard)
  • HY-N12156
    Ajugasterone C 2-acetate

    		Others Others
    Ajugasterone C 2-acetate is an ecdysteroid that can be isolated from Cyanotis arachnoidea .
    Ajugasterone C 2-acetate
  • HY-113890R
    Halofenozide (Standard)

    		Others Others
    Halofenozide (Standard) is the analytical standard of Halofenozide. This product is intended for research and analytical applications. Halofenozide (RH-0345) is an ecdysteroid agonist. RH-0345 belongs to a new group of insect growth regulators (IGRs) with a benzoylhydrazine structure that mimic the action of the natural insect molting hormone 20-hydroxyecdysone .
    Halofenozide (Standard)
  • HY-N6979R
    Crustecdysone (Standard)

    		Caspase Autophagy Endogenous Metabolite Cardiovascular Disease
    Crustecdysone (Standard) is the analytical standard of Crustecdysone. This product is intended for research and analytical applications. Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .
    Crustecdysone (Standard)
  • HY-N10382
    20,26-Dihydroxyecdysone

    		Drug Metabolite Others
    20,26-Dihydroxyecdysone is a predominant ecdysteroid metabolite .
    20,26-Dihydroxyecdysone
  • HY-N12867
    Amarasterone A

    		Others Endocrinology
    Amarasterone A (22) is an ecdysteroid that can be isolated from Rhaponticum carthamoides .
    Amarasterone A
  • HY-103273
    Muristerone A

    		Endogenous Metabolite Others
    Muristerone A is a phytoecdysteroid analog of ecdysone and a potent agonist of ecdysteroid receptor with a Kd of 1 nM .
    Muristerone A
  • HY-N3792
    20-Hydroxyecdysone 2,3:20,22-diacetonide

    		Others Metabolic Disease
    20-Hydroxyecdysone 2,3:20,22-diacetonide is a natural ecdysteroid .
    20-Hydroxyecdysone 2,3:20,22-diacetonide
  • HY-N10746
    Polyporoid C

    		Others Inflammation/Immunology
    Polyporoid C is a ergostane-type ecdysteroid that exhibits potent anti-inflammatory activity in vivo .
    Polyporoid C
  • HY-N10747
    Polyporoid B

    		Others Inflammation/Immunology
    Polyporoid B is a ergostane-type ecdysteroid that exhibits potent anti-inflammatory activity in vivo .
    Polyporoid B
  • HY-N11081
    Hexanorcucurbitacin D

    		FXR Cardiovascular Disease
    Hexanorcucurbitacin D, a cucurbitacin, is a weak ecdysteroid receptor agonist. Hexanorcucurbitacin D can be isolated from Trichosanthes cucumeroides roots. Hexanorcucurbitacin D can be used for the research of cardiovascular disease (CVD) .
    Hexanorcucurbitacin D
  • HY-118541
    RH-5849

    		Insecticide Others
    RH-5849 is an orally active agonist for non-steroidal ecdysteroid, which inhibits the larval growth of Plodia inferpuncteila in a dose-dependent manner. RH-5849 exhibits molting hormone activity .
    RH-5849
  • HY-N2196
    Ajugasterone C

    		Others Inflammation/Immunology
    Ajugasterone C is an ecdysteroid isolated from Leuzea carthamoides. Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to Carrageenan-induced inflammation in Sprague Dawley rats .
    Ajugasterone C
  • HY-124097
    HNMPA-(AM)3

    		Insulin Receptor Metabolic Disease
    HNMPA-(AM)3 is a cell-permeable and selective insulin receptor tyrosine kinase inhibitor analog of HNMPA. HNMPA-(AM)3 greatly inhibits the ability of prothoracicotropic hormone (PTTH) to activate ERK phosphorylation and stimulate ecdysteroidogenesis. HNMPA-(AM)3 is also effective in inhibiting ecdysteroid production (IC50=14.2 μM) and insulin receptor activity (IC50 is 14.2 μM and 200 μM in mosquitoes and mammals, respectively) .
    HNMPA-(AM)3

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