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Dermatophytes

" in MedChemExpress (MCE) Product Catalog:

39

Inhibitors & Agonists

1

Fluorescent Dye

1

Biochemical Assay Reagents

1

Peptides

8

Natural
Products

6

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16246
    Haloprogin

    		Fungal Infection
    Haloprogin is a potent antifungal agent. Haloprogin has activity against dermatophytes, Candida spp and a limited number of Gram-positive bacteria .
    Haloprogin
  • HY-108012
    ME1111

    		Fungal Infection
    ME1111 is an antifungal agent that is active against dermatophytes. ME1111 is an inhibitor of the succinate dehydrogenase of Trichophyton species. ME1111 has an excellent ability to penetrate human nails and is used for onychomycosis research .
    ME1111
  • HY-B0348
    Liranaftate

    Piritetrate; M-732

    		 Fungal Infection
    Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation .
    Liranaftate
  • HY-B0518A
    Naftifine hydrochloride

    		Fungal Antibiotic Infection
    Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .
    Naftifine hydrochloride
  • HY-17643
    Oteseconazole
    1 Publications Verification

    VT-1161

    		 Fungal Cytochrome P450 Infection
    Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes .
    Oteseconazole
  • HY-162296
    Antibacterial agent 188

    		Fungal Infection
    Antibacterial agent 188 (compound 2d) is an antibacterial agent that inhibits dermatophyte activity .
    Antibacterial agent 188
  • HY-118451
    Lanomycin

    		Fungal Infection
    Lanomycin is an antifungal compound with activity against Candida and dermatophytes .
    Lanomycin
  • HY-N3041
    Plumieride

    Agoniadin; NSC 609065

    		 Fungal Infection Cancer
    Plumieride is an antifungal agent. Plumieride has strong fungitoxicity against some dermatophytes. Plumieride has little cytotoxic activity against the P388 leukaemia cell line with an IC50 of 85 μg/mL .
    Plumieride
  • HY-17643R
    Oteseconazole (Standard)

    		Fungal Cytochrome P450 Infection
    Oteseconazole (Standard) is the analytical standard of Oteseconazole. This product is intended for research and analytical applications. Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes .
    Oteseconazole (Standard)
  • HY-B0348R
    Liranaftate (Standard)

    		Fungal Infection
    Liranaftate (Standard) is the analytical standard of Liranaftate. This product is intended for research and analytical applications. Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation .
    Liranaftate (Standard)
  • HY-B0518AR
    Naftifine (hydrochloride) (Standard)

    		Fungal Antibiotic Infection
    Naftifine (hydrochloride) (Standard) is the analytical standard of Naftifine (hydrochloride). This product is intended for research and analytical applications. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .
    Naftifine (hydrochloride) (Standard)
  • HY-114518
    Butenafine

    KP363

    		 Fungal Infection
    Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent . Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as  tinea pedis,  tinea cruris, tinea versicolor .
    Butenafine
  • HY-114518S2
    Butenafine-d4

    KP363-d4

    		 Fungal Isotope-Labeled Compounds Infection
    Butenafine-d4 (KP363-d4) is the deuterium labeled Butenafine (HY-114518). Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent . Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as ?tinea pedis, ?tinea cruris, tinea versicolor .
    Butenafine-d4
  • HY-121924
    L-689065

    		Bacterial Infection
    Chloracetophos is a fungicide with potential to inhibit dermatophytes .
    L-689065
  • HY-40284A
    3-Piperidinopropiophenone hydrochloride

    		Fungal Infection
    3-Piperidinopropiophenone (hydrochloride) (Compound 2) is a mono Mannich base derived from acetophenone and has antifungal activity .
    3-Piperidinopropiophenone hydrochloride
  • HY-129585
    SM-4470

    		Fungal Infection
    SM-4470 is an orally active antifungal compound. SM-4470 has inhibitory activity against yeast, Aspergillus, and dermatophytes in vitro .
    SM-4470
  • HY-19584
    Variotin

    		Fungal Infection
    Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus .
    Variotin
  • HY-17583S
    Griseofulvin-d3

    		Isotope-Labeled Compounds Fungal Apoptosis Antibiotic Endogenous Metabolite Infection Cancer
    Griseofulvin-d3 is the deuterium labeled Griseofulvin. Griseofulvin (Gris-PEG) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal agent .
    Griseofulvin-d3
  • HY-N14177
    Cyathin A4

    		Bacterial Infection
    Cyathin A4 has weak activity against Gram-positive bacteria, negative bacteria, actinomycetes and dermatophytes, and has anti-ischemia effect (improving cerebral ischemia in rat model) .
    Cyathin A4
  • HY-N14176
    Cyathin A3

    		Bacterial Infection
    Cyathin A3 has weak activity against Gram-positive bacteria, negative bacteria, actinomycetes and dermatophytes, and has anti-ischemia effect (improving cerebral ischemia in rat model) .
    Cyathin A3
  • HY-10445
    Pramiconazole

    Azoline; R126638

    		 Fungal Infection
    Pramiconazole is a broad-spectrum antifungal agent with oral activity. Pramiconazole has a good affinity for 14α-demethylase. Pramiconazole can be used in the study of fungal infections in the local skin, hair, nails, oral cavity, and genital mucosa .
    Pramiconazole
  • HY-B0518AS
    Naftifine-d3 hydrochloride

    		Isotope-Labeled Compounds Fungal Antibiotic Infection
    Naftifine-d3 (hydrochloride) is the deuterium labeled Naftifine hydrochloride. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .
    Naftifine-d3 hydrochloride
  • HY-N2472
    Medicagenic acid

    Castanogenin

    		 Bacterial Xanthine Oxidase Infection
    Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes . Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE .
    Medicagenic acid
  • HY-136767
    Cladosporin

    		Antibiotic Fungal Bacterial Parasite DNA/RNA Synthesis Infection
    Cladosporin is an antibiotic and an an antifungal metabolite that can be produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin exhibits inhibitory activity against various dermatophytes, plant pathogens, and bacteria. Cladosporin also exhibits antimalarial activity through inhibition of cytoplasmic lysine-tRNA synthetase of Plasmodium (PfKrs1) .
    Cladosporin
  • HY-B0450S1
    Ciclopirox-d11 sodium

    		Isotope-Labeled Compounds Fungal Bacterial Ferroptosis Autophagy Infection Cancer
    Ciclopirox-d11 (sodium) is deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .
    Ciclopirox-d11 sodium
  • HY-B0450S
    Ciclopirox-d11

    HOE296b-d11

    		 Fungal Bacterial Ferroptosis Autophagy Infection Cancer
    Ciclopirox-d11 is the deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .
    Ciclopirox-d11
  • HY-106546
    Tolciclate

    KC 9147

    		 Fungal Infection
    Tolciclate (KC 9147) is an antifungal agent with in vitro inhibitory activity against dermatophytes, effective at concentrations of 0.01-0.1 μg/mL. Tolciclate is colorless and soluble in well-tolerated excipients, and it is more lipophilic than Tolnaftate (HY-B0370). Tolciclate can be used in research related to antifungal infections .
    Tolciclate
  • HY-B0319R
    Tioconazole (Standard)

    		Fungal Antibiotic Infection
    Tioconazole (Standard) is the analytical standard of Tioconazole. This product is intended for research and analytical applications. Tioconazole (UK-20349) is an antifungal imidazole derivative with broad spectrum activity. Tioconazole has inhibitory active aginst several dermatophytes and several yeasts with MIC50s <3.12 mg/L and <9 mg/L, respectively .
    Tioconazole (Standard)
  • HY-15660
    Efinaconazole
    2 Publications Verification

    KP-103

    		 Fungal Infection
    Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively . Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species .
    Efinaconazole
  • HY-111333
    Pyrroxamycin

    Dioxapyrrolomycin; LL-F42248α; AL-R2081

    		 Bacterial Infection
    Pyrroxamycin is a novel antibiotic produced by Streptomyces, whose chemical structure was determined by chemical properties and X-ray crystallography and 13C NMR spectroscopy analysis. It is active against Gram-positive bacteria and dermatophytes. In this paper, the authors discuss the taxonomy, fermentation, isolation, physicochemical properties, chemical structure, and biological activity of the strain producing Pyrroxamycin.
    Pyrroxamycin
  • HY-B0450
    Ciclopirox
    Maximum Cited Publications
    7 Publications Verification

    HOE296b

    		 Fungal Bacterial Ferroptosis Autophagy Infection Inflammation/Immunology Cancer
    Ciclopirox (HOE296b) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox also has anticancer and anti-inflammatory effect .
    Ciclopirox
  • HY-B0450A
    Ciclopirox olamine
    Maximum Cited Publications
    7 Publications Verification

    Ciclopirox ethanolamine; HOE 296

    		 Fungal Bacterial Ferroptosis Infection Cancer
    Ciclopirox olamine (Ciclopirox ethanolamine) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox olamine also has anticancer and anti-inflammatory effect .
    Ciclopirox olamine
  • HY-N2472R
    Medicagenic acid (Standard)

    Castanogenin (Standard)

    		 Xanthine Oxidase Bacterial Infection
    Medicagenic acid (Standard) is the analytical standard of Medicagenic acid. This product is intended for research and analytical applications. Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes . Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE .
    Medicagenic acid (Standard)
  • HY-15660S
    Efinaconazole-d4

    KP-103-d4

    		 Isotope-Labeled Compounds Fungal Infection
    Efinaconazole-d4 is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively . Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species .
    Efinaconazole-d4
  • HY-169684
    Vaccarin C

    		Fungal Infection Cancer
    Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with IC50 values of 3.35 and 5.72 μM, respectively .
    Vaccarin C
  • HY-B0450R
    Ciclopirox (Standard)

    		Fungal Bacterial Ferroptosis Autophagy Infection Inflammation/Immunology Cancer
    Ciclopirox (Standard) is the analytical standard of Ciclopirox. This product is intended for research and analytical applications. Ciclopirox (HOE296b) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox also has anticancer and anti-inflammatory effect .
    Ciclopirox (Standard)
  • HY-B0450AR
    Ciclopirox (olamine) (Standard)

    		Fungal Bacterial Ferroptosis Infection Cancer
    Ciclopirox (olamine) (Standard) is the analytical standard of Ciclopirox (olamine). This product is intended for research and analytical applications. Ciclopirox olamine (Ciclopirox ethanolamine) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox olamine also has anticancer and anti-inflammatory effect .
    Ciclopirox (olamine) (Standard)
  • HY-B0450AG
    Ciclopirox olamine

    Ciclopirox ethanolamine; HOE 296

    		 Bacterial Fungal Ferroptosis Infection
    Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .
    Ciclopirox olamine
  • HY-B0319
    Tioconazole
    1 Publications Verification

    UK-20349

    		 Fungal Antibiotic Parasite Akt PI3K mTOR Autophagy Infection Cancer
    Tioconazole (UK-20349) is a broad-spectrum antifungal imidazole derivative. Tioconazole inhibits several dermatophytes and yeasts, with MIC50 values of less than 3.12 mg/L and 9 mg/L, respectively. Additionally, Tioconazole exhibits anti-parasitic activity. Tioconazole exerts anticancer activity by inhibiting the PI3K/AKT/mTOR signaling pathway and blocking autophagy. Tioconazole is applicable for research in the fields of anti-infection and anticancer therapy .
    Tioconazole

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