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Results for "

DPA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5 alpha Reductase (1) Biochemical Assay Reagents (2) CCR (1) Checkpoint Kinase (Chk) (1) CXCR (1) Cytochrome P450 (1) Drug Derivative (3) Drug Intermediate (2) Drug Isomer (1) Fluorescent Dye (3) FXR (1) Interleukin Related (1) Mitochondrial Metabolism (2) MMP (3) NF-κB (1) PPAR (1) Small Interfering RNA (siRNA) (1) STAT (1) TNF Receptor (1) TSPO (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (2) Inflammation/Immunology (6) Neurological Disease (2)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-122607

DPA-714	Mitochondrial Metabolism TSPO	Inflammation/Immunology Cancer
DPA-714 is a high affinity translocator protein (TSPO) ligand (K_i=7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. ^18FDPA-714 successfully evaluates for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model .

HY-P3722A

*Mca-PLAQAV-Dpa-RSSSR-NH2 TFA*	Fluorescent Dye MMP	Others
Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent peptide and as one of fluorescent substrates of TNF-α converting enzyme (TACE): ADAM17, ADAM 9 and ADAM 10. Mca-PLAQAV-Dpa-RSSSR-NH2 is a substrate based on fluorescence resonance energy transfer, and its activity can be determined by the change of fluorescence intensity during pyrolysis .

HY-400882

*Tosylate-DPA-714*	Drug Derivative	Neurological Disease Inflammation/Immunology
Tosylate-DPA-714 (compound 2) is a DPA-714 (HY-122607) tosylate analog. Tosylate-DPA-714 is a precursor for ¹⁸F-DPA-714. DPA-714 is a translocator protein (TSPO)-specific ligand .

HY-131498

*MOCAc-PLGL(Dpa)AR* Mca-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2	Fluorescent Dye	Others
MOCAc-PLGL(Dpa)AR is a positively charged fluorescent substrate for matrix metalloproteinase-2 (MMP-2), MMP-7 and MMP-9. MOCAc-PLGL(Dpa)AR is a substrate of matrilysin, can be cleaved at the peptide bond between the glycine and leucine residues .

HY-W189421

Diphenic anhydride DPA	Biochemical Assay Reagents	Others
Diphenic anhydride (DPA) is a versatile reagent that can be used as a catalyst in many organic synthetic processes, such as polymer synthesis .

HY-122607R

DPA-714 (Standard)	Mitochondrial Metabolism	Inflammation/Immunology Cancer
DPA-714 (Standard) is the analytical standard of DPA-714. This product is intended for research and analytical applications. DPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. 18FDPA-714 successfully evaluates for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model .

HY-B1734

16-Dehydropregnenolone acetate 16-DPA	FXR 5 alpha Reductase Cytochrome P450 Drug Intermediate	Cardiovascular Disease Cancer
16-Dehydropregnenolone acetate (16-DPA), a sterols compound, is an orally active 17α-hydroxylase and 5α-reductase inhibitor. 16-Dehydropregnenolone is also a potent bile acid receptor (BAR)/farnesoid X receptor (FXR) antagonist. 16-Dehydropregnenolone hypolipidemic and anticancer effects. 16-Dehydropregnenolone acetate (16-DPA) is the drug intermediate that can be used for synthesis of Dexamethasone (HY-14648) and related other steroidal pharmacophores .

HY-151559

*Zn-DPA-maytansinoid conjugate 1*	Checkpoint Kinase (Chk) STAT CXCR CCR	Cancer
Zn-DPA-maytansinoid conjugate 1 is a small molecule-based maytansinoid conjugate targeting immune checkpoint. Zn-DPA-maytansinoid conjugate 1 induces lasting regression of tumor growth and rejuvenates tumor microenvironment (TME) to an "inflamed hot tumor" .

HY-168782

Resolvin D2 n-3 DPA	TNF Receptor Interleukin Related	Inflammation/Immunology
Resolvin D2 n-3 DPA is a specialized proresolving mediator (SPM). Resolvin D2 n-3 DPA (1 nM) can reduce the chemotaxis and adhesion of human neutrophils induced by TNF-α. Resolvin D2 n-3 DPA (100 ng/mouse; intravenous injection) can reduce neutrophil infiltration in the peritoneum and the levels of IL-6 and the chemokine (C-C motif) ligand 2 (CCL2) in a mouse model of inflammation induced by zinc oxide .

HY-RS06203

*HLA-DPA1 Human Pre-designed siRNA Set A*	Small Interfering RNA (siRNA)	Others
HLA-DPA1 Human Pre-designed siRNA Set A contains three designed siRNAs for HLA-DPA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HLA-DPA1 Human Pre-designed siRNA Set A HLA-DPA1 Human Pre-designed siRNA Set A

HY-P3722

*Mca-PLAQAV-Dpa-RSSSR-NH2*	Fluorescent Dye MMP	Others
Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent peptide and as one of fluorescent substrates of TNF-α converting enzyme (TACE; ADAM17), ADAM 9 and ADAM 10. Mca-PLAQAV-Dpa-RSSSR-NH2 is a substrate based on fluorescence resonance energy transfer, and its activity can be determined by the change of fluorescence intensity during pyrolysis .

HY-W923496

all-cis-4,7,10,13,16-Docosapentaenoic acid ethyl ester SFE 24:5; all-cis-4,7,10,13,16-DPA Ethyl ester	Drug Derivative	Others
all-cis-4,7,10,13,16-Docosapentaenoic acid ethyl ester (SFE 24:5) is a derivative of Docosapentaenoic acid (DPA). DPA is a fatty acid found in fish oils .

HY-W088320

4-Hydroxydiphenylamine p-Anilinophenol; 4-Hydroxy-DPA	Drug Intermediate	Others
4-Hydroxydiphenylamine (p-Anilinophenol; 4-Hydroxy-DPA) is an aromatic amine organic compound. 4-Hydroxydiphenylamine has antioxidant activity and is also used as a catalyst or intermediate in some chemical reactions to synthesize other compounds. 4-Hydroxydiphenylamine can be used in the research of environmental science and toxicology .

HY-W746625

all-cis-4,7,10,13,16-Docosapentaenoic acid methyl ester all-cis-4,7,10,13,16-DPA methyl ester	Drug Derivative	Cardiovascular Disease Neurological Disease Inflammation/Immunology
all-cis-4,7,10,13,16-Docosapentaenoic acid methyl ester (all-cis-4,7,10,13,16-DPA methyl ester) is the methyl ester derivative of all-cis-4,7,10,13,16-Docosapentaenoic acid, that can be used as a nutritional supplement to increase all-cis-4,7,10,13,16-Docosapentaenoic acid intake. all-cis-4,7,10,13,16-Docosapentaenoic acid is a long-chain polyunsaturated fatty acid, that plays a role in cardiovascular health, neuroprotection, and inflammation regulation .

HY-116115

17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid 17-Oxo-DPA; 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA	NF-κB PPAR	Inflammation/Immunology
17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid (17-Oxo-DPA; 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA) is an electrophilic oxo-derivative (EFOX) of the docosahexaenoic acid (DHA) (HY-B2167). 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is generated during inflammation by COX-2-catalyzed mechanism in activated macrophages. 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid acts as an agonist for PPARγ and a modulator for NF-κB signaling pathway, inhibits the production of pro-inflammatory cytokines and nitric oxide, and exhibits anti-inflammatory efficacy .

HY-N7864

Osbond acid all-cis-4,7,10,13,16-Docosapentaenoic acid	Biochemical Assay Reagents	Others
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-165071

(±)16(17)-EpDPA (±)16,17 EDP; (±)16,17-Epoxy docosapentaenoic acid; (±)16,17-Epoxy DPA	Drug Isomer	Others
(±)16(17)-EpDPA is the DHA homolog of (±)14(15)-EpETrE, derived via epoxidation of the 16,17-double bond of DHA.

HY-P4931

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 1 Publications Verification Mca-Lys-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2	MMP	Cancer
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)

Cat. No.	Product Name	Type

HY-131498

*MOCAc-PLGL(Dpa)AR* Mca-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2	Fluorescent Dyes/Probes
MOCAc-PLGL(Dpa)AR is a positively charged fluorescent substrate for matrix metalloproteinase-2 (MMP-2), MMP-7 and MMP-9. MOCAc-PLGL(Dpa)AR is a substrate of matrilysin, can be cleaved at the peptide bond between the glycine and leucine residues .

Cat. No.	Product Name	Type

HY-N7864

Osbond acid all-cis-4,7,10,13,16-Docosapentaenoic acid	Cell Assay Reagents
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

Osbond acid

all-cis-4,7,10,13,16-Docosapentaenoic acid

Cell Assay Reagents

Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-W189421

Diphenic anhydride DPA	Biochemical Assay Reagents
Diphenic anhydride (DPA) is a versatile reagent that can be used as a catalyst in many organic synthetic processes, such as polymer synthesis .

Cat. No.	Product Name	Target	Research Area

HY-P3722A

*Mca-PLAQAV-Dpa-RSSSR-NH2 TFA*	Fluorescent Dye MMP	Others
Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent peptide and as one of fluorescent substrates of TNF-α converting enzyme (TACE): ADAM17, ADAM 9 and ADAM 10. Mca-PLAQAV-Dpa-RSSSR-NH2 is a substrate based on fluorescence resonance energy transfer, and its activity can be determined by the change of fluorescence intensity during pyrolysis .

HY-P4931

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 1 Publications Verification Mca-Lys-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2	MMP	Cancer
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)

HY-P3722

*Mca-PLAQAV-Dpa-RSSSR-NH2*	Fluorescent Dye MMP	Others
Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent peptide and as one of fluorescent substrates of TNF-α converting enzyme (TACE; ADAM17), ADAM 9 and ADAM 10. Mca-PLAQAV-Dpa-RSSSR-NH2 is a substrate based on fluorescence resonance energy transfer, and its activity can be determined by the change of fluorescence intensity during pyrolysis .

Cat. No.	Compare	Product Name	Species	Source

HY-P71697

	*HLA-DPA1 Protein, Human (His)* HLA-DPA1; HLA-DP1A; HLASBHLA class II histocompatibility antigen; DP alpha 1 chain; HLA-SB alpha chain; MHC class II DP3-alpha; MHC class II DPA1	Human	E. coli
	The HLA-DPA1 protein is critical in the immune system, binding antigens in the endocytic pathway of APCs and presenting them to the cell surface for recognition by CD4 T cells. The peptide binding cleft can accommodate peptides of 10-30 residues, mainly resulting from protein degradation. HLA-DPA1 Protein, Human (His) is the recombinant human-derived HLA-DPA1 protein, expressed by E. coli , with N-His labeled tag.

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HY-P84161

	*HLA-DPA1 Antibody (YA3858)* DPA1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DPA; HLA-DP1A; HLA-DPB1	WB, IHC-P, FC, ELISA	Human
	HLA-DPA1 Antibody (YA3858) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to HLA-DPA1.

HY-P84162

	*HLA-DPA1 Antibody (YA3859)* DPA1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DPA; HLA-DP1A; HLA-DPB1	IHC-P, FC, ELISA	Human, Rat
	HLA-DPA1 Antibody (YA3859) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to HLA-DPA1.

HY-P81436

	*HLA-DPA1 Antibody (YA1181)* HLA DPA1; major histocompatibility complex; class II; DP alpha 1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DP1A	IHC-P	Human
	HLA-DPA1 Antibody (YA1181) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HLA-DPA1.

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*HLA-DPA1 Human Pre-designed siRNA Set A*		siRNAs Human Pre-designed siRNA Sets
HLA-DPA1 Human Pre-designed siRNA Set A contains three designed siRNAs for HLA-DPA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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