2. Search Result
Search Result
Results for "

DMBA

" in MedChemExpress (MCE) Product Catalog:

21

Inhibitors & Agonists

2

Biochemical Assay Reagents

1

Inhibitory Antibodies

6

Natural
Products

1

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W011845
    DMBA

    7,12-DMBA; 7,12-Dimethylbenzanthracene

    		 c-Myc Cancer
    DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models .
    DMBA
  • HY-126573
    Trilaurin

    		Endogenous Metabolite Cancer
    Trilaurin could inhibit the formation of neoplasms initiated by dimethylbenzanthracene (DMBA) and promoted by croton oil .
    Trilaurin
  • HY-N0679
    Retinyl acetate
    2 Publications Verification

    Retinol acetate; Vitamin A acetate

    		 Others Cancer
    Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities .
    Retinyl acetate
  • HY-W543743
    1-Ethenylpyrene

    1-Vinylpyrene

    		 Biochemical Assay Reagents Cancer
    1-Ethenylpyrene (1-Vinylpyrene) is an anti-chemical carcinogen that inhibits the formation of skin tumors initiated by either DMBA (HY-W011845) or Benzo[a]pyrene (HY-107377) .
    1-Ethenylpyrene
  • HY-W011845R
    DMBA (Standard)

    		c-Myc Cancer
    DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models .
    DMBA (Standard)
  • HY-160702
    DMBA-SIL-Mal-MMAE

    		Drug-Linker Conjugates for ADC Cancer
    DMBA-SIL-Mal-MMAE is a cytotoxin-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked DMBA-SIL-Mal .
    DMBA-SIL-Mal-MMAE
  • HY-160703
    DMBA-SIL-PNP

    		Drug Intermediate Cancer
    DMBA-SIL-PNP (Compound 5) is an intermediate used for preparing Drug-Linker Conjugates, which can be applied in cancer research .
    DMBA-SIL-PNP
  • HY-126573R
    Trilaurin (Standard)

    		Reference Standards Others Cancer
    Trilaurin (Standard) is the analytical standard of Trilaurin. This product is intended for research and analytical applications. Trilaurin could inhibit the formation of neoplasms initiated by dimethylbenzanthracene (DMBA) and promoted by croton oil .
    Trilaurin (Standard)
  • HY-N0679R
    Retinyl acetate (Standard)

    Retinol acetate (Standard); Vitamin A acetate (Standard)

    		 Reference Standards Others Cancer
    Retinyl acetate (Standard) is the analytical standard of Retinyl acetate. This product is intended for research and analytical applications. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities .
    Retinyl acetate (Standard)
  • HY-19590
    Etarotene

    Ro 15-1570

    		 Drug Derivative Cancer
    Etarotene (Ro 15-1570) is a derivative of Arotinoid (HY-106735). Etarotene is an orally active antitumor agent against DMBA (HY-W011845)-induced mammary tumor and causes toxic symptoms of hypervitaminosis A in rat model .
    Etarotene
  • HY-N15456
    Cryptolepinone

    		Quinone Reductase Cancer
    Cryptolepinone is a quinone reductase activator with a CD (concentration required to double induction) value of 0.02 μg/mL and can be found in Sida acuta. In the mouse mammary organ culture assay, 10 μg/mL of Cryptolepinone inhibited 83.3% of the preneoplastic lesions induced by DMBA (HY-W011845). Cryptolepinone can be used in anti-cancer research .
    Cryptolepinone
  • HY-124403
    D 15413

    		Estrogen Receptor/ERR Cancer
    D 15413 is an orally active antagonist for nonsteroidal estrogen. D 15413 inhibits growth of estrogen receptor positive MCF-7 cell with an inhibition rate of 70% at 10 -7 M. D 15413 exhibits antitumor efficacy against DMBA (HY-W011845) or MNU (HY-34758)-induced breast cancer .
    D 15413
  • HY-16290
    Lonaprisan

    ZK 230211; BAY86 5044

    		 Progesterone Receptor Endocrinology
    Lonaprisan (ZK 230211; BAY86 5044) is an antagonist for progesterone receptor, with IC50 of 3.6 pM and 2.5 pM for PR-A and PR-B, respectively. Lonaprisan exhibits antiprogestagenic activity in rabbits, interrupts early pregnancy in rats, and exhibits antitumor efficacy against DMBA (HY-W011845)-induced mammary tumor. Lonaprisan reveals antiglucocorticoid and antiandrogenic effect .
    Lonaprisan
  • HY-B0860
    Diuron
    1 Publications Verification

    		 Herbicide Reactive Oxygen Species (ROS) MDM-2/p53 Cancer
    Diuron is an orally active phenylurea herbicide. Diuron inhibits photosynthesis in plants by blocking the formation of ATP and NADH. Diuron increases the production of ROS. Diuron increases expression of p53 in certain cell lines. Diuron has herbicidal activity against annual and perennial broadleaf weeds and grass weeds. Diuron promotes DMBA/BBN-induced bladder cancer. Diuron can be used in breast cancer research .
    Diuron
  • HY-110002
    LFM-A13
    1 Publications Verification

    		 Polo-like Kinase (PLK) Btk JAK Cancer
    LFM-A13 is a potent BTK, JAK2, PLK inhibitor, inhibits recombinant BTK, Plx1 and PLK3 with IC50s of 2.5 μM, 10 μM and 61 μM. LFM-A13 has antiproliferative activity and anticancer activity. LFM-A13 can be used in cancer-related research
    LFM-A13
  • HY-B0860S
    Diuron-d6

    		Isotope-Labeled Compounds Herbicide Reactive Oxygen Species (ROS) MDM-2/p53 Cancer
    Diuron-d6 is the deuterium labeled Diuron (HY-B0860). Diuron is an orally active phenylurea herbicide. Diuron inhibits photosynthesis in plants by blocking the formation of ATP and NADH. Diuron increases the production of ROS. Diuron increases expression of p53 in certain cell lines. Diuron has herbicidal activity against annual and perennial broadleaf weeds and grass weeds. Diuron promotes DMBA/BBN-induced bladder cancer. Diuron can be used in breast cancer research .
    Diuron-d6
  • HY-B0860R
    Diuron (Standard)

    		Herbicide Reference Standards Reactive Oxygen Species (ROS) MDM-2/p53 Cancer
    Diuron (Standard) is the analytical standard of Diuron (HY-B0860). This product is intended for research and analytical applications. Diuron is an orally active phenylurea herbicide. Diuron inhibits photosynthesis in plants by blocking the formation of ATP and NADH. Diuron increases the production of ROS. Diuron increases expression of p53 in certain cell lines. Diuron has herbicidal activity against annual and perennial broadleaf weeds and grass weeds. Diuron promotes DMBA/BBN-induced bladder cancer. Diuron can be used in breast cancer research .
    Diuron (Standard)
  • HY-114631
    EM-800

    		Estrogen Receptor/ERR Cancer
    EM-800, an orally active anti-estrogen, serves as an antagonist to the transcriptional functions of estrogen receptors α (ERα) and β (ERβ). EM-800 possesses anticancer activity, capable of inhibiting the growth of breast cancer induced by 7,12-Dimethylbenz[a]anthracene (DMBA) (HY-W011845). Furthermore, in ovariectomized animals, EM-800 effectively slows down bone loss. Additionally, EM-800 shows potential in the research of breast and endometrial cancers, while exerting beneficial effects on bone and lipid metabolism .
    EM-800
  • HY-P991358
    XOMA-213

    LFA-102; X213

    		 Estrogen Receptor/ERR Cancer
    XOMA-213 (LFA-102; X213) is a human monoclonal antibody (mAb) targeting PRLR/Prolactin Receptor. XOMA-213 inhibits hPRL-dependent growth of BaF3/hPRLR cells (EC50: 0.5 μg/mL). XOMA-213 inhibits PRLR signaling and tumor growth in the Nb2-11-luc xenograft mouse model and the DMBA-induced rat breast cancer model. XOMA-213 can be used in Breast cancer, Hyperprolactinaemia and Prostate cancer research .
    XOMA-213
  • HY-Y1881A
    Copper sulfate pentahydrate, 99.9%

    		Biochemical Assay Reagents Reactive Oxygen Species (ROS) MyD88 SOD Caspase Neurological Disease Metabolic Disease Cancer
    Copper sulfate pentahydrate, 99% is a biochemical reagent. Copper sulfate pentahydrate, 99% reduces the production of ROS and the expression levels of MyD88 as well as c-Rel genes. Copper sulfate pentahydrate, 99% decreases the activities of T-SOD, CAT, and GSH, increases the activities of caspase-3, caspase-8, and caspase-9. Copper sulfate pentahydrate, 99% is cytotoxic to various cells. Copper sulfate pentahydrate, 99% has antioxidant activity. Copper sulfate pentahydrate, 99% can be used in the research of diabetes, Parkinson's disease and DMBA (HY-W011845)-induced tumors .
    Copper sulfate pentahydrate, 99.9%
  • HY-N15378
    β-Carotene-15,15'-epoxide

    		IAP Bcl-2 Family COX TNF Receptor Caspase Apoptosis Inflammation/Immunology Cancer
    β-carotene-15,15ʹ-epoxide is a XIAP antagonist with apoptosis-inducing and antitumor activity, found in the leaves of Spondias mombin. In a DMBA (HY-W011845)-induced rat model of breast cancer, β-carotene-15,15ʹ-epoxide binds to the BIR3 domain of the anti-apoptotic protein XIAP, blocking its interaction with caspase-9 and thereby promoting tumor cell apoptosis. In addition, β-carotene-15,15ʹ-epoxide significantly downregulates the expression of BCL-2, COX-2, and TNF-α in tumor tissues, reduces MDA levels, increases catalase activity, and modulates serum levels of LDH, ALP, and ALT, demonstrating strong antioxidant, anti-inflammatory, and metabolic protective effects. β-carotene-15,15ʹ-epoxide may be used in research on inflammation-related conditions and cancers such as breast cancer .
    β-Carotene-15,15'-epoxide

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: