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DHODH-IN-32

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-178941
    DHODH-IN-32

    		Dihydroorotate Dehydrogenase Apoptosis Caspase Reactive Oxygen Species (ROS) Cancer
    DHODH-IN-32 (Compound A1) is a DHODH inhibitor. DHODH-IN-32 shows significant cytotoxicity against NCI-60 cell lines, especially being sensitive to breast cancer, prostate cancer and leukemia cell lines. DHODH-IN-32 can induce cell apoptosis by activating the Caspase pathway. DHODH-IN-32 causes G0/G1 phase cell cycle arrest and inhibits cellular metabolism by ROS. DHODH-IN-32 exhibits significant anti-tumor properties in mouse breast cancer models. DHODH-IN-32 can be used for the study of breast cancer .
    DHODH-IN-32

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