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Results for "

DCC

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

4

Fluorescent Dye

2

Biochemical Assay Reagents

2

Natural
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1

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1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-160699
    DCC-3116

    		ULK Ras Cancer
    DCC-3116 is an orally active ULK1/2 inhibitor. DCC-3116 can promote autophagy in lung cancer cells by inhibiting KRAS G12C signaling, thereby inhibiting the proliferation of lung cancer cells and exerting anti-cancer effects .
    DCC-3116
  • HY-112306
    Ripretinib
    1 Publications Verification

    DCC-2618

    		 c-Kit PDGFR FLT3 VEGFR Apoptosis Cancer
    Ripretinib (DCC-2618) is an orally bioavailable, selective KIT and PDGFRA switch-control inhibitor. Ripretinib (DCC-2618) targets and binds to both wild-type and mutant forms of KIT and PDGFRA specifically at their switch pocket binding sites, thereby preventing the switch from inactive to active conformations of these kinases and inactivating their wild-type and mutant forms. Ripretinib (DCC-2618) also inhibits multiple other kinase targets, such as FLT3 and KDR (or VEGFR-2) . DCC-2618 exerts antineoplastic effect and induces apoptosis .
    Ripretinib
  • HY-136256
    Vimseltinib

    DCC-3014

    		 c-Fms c-Kit Cancer
    Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor extracted from patent WO2014145025A2, Compound Example 10, has IC50s of <0.01 μM and 0.1-1 μM, respectively .
    Vimseltinib
  • HY-B0791
    Altiratinib
    1 Publications Verification

    DCC-2701

    		 VEGFR c-Met/HGFR FLT3 Trk Receptor Cancer
    Altiratinib (DCC-2701) is a multi-targeted kinase inhibitor with IC50s of 2.7, 8, 9.2, 9.3, 0.85, 4.6, 0.83 nM for MET, TIE2, VEGFR2, FLT3, Trk1, Trk2, and Trk3 respectively.
    Altiratinib
  • HY-13024
    Rebastinib
    Maximum Cited Publications
    7 Publications Verification

    DCC-2036

    		 Bcr-Abl FLT3 Src Apoptosis Cancer
    Rebastinib (DCC-2036) is an orally active, non-ATP-competitive Bcr-Abl inhibitor for Abl1 WT and Abl1 T315I with IC50s of 0.8 nM and 4 nM, respectively. Rebastinib also inhibits SRC, KDR, FLT3, and Tie-2, and has low activity to seen towards c-Kit.
    Rebastinib
  • HY-Y1092
    N,N-Dicyclohexylcarbodiimide(DCC)

    		Biochemical Assay Reagents Adenylate Cyclase Others
    N,N-Dicyclohexylcarbodiimide(DCC) is a dehydrating and condensing agent. N,N-Dicyclohexylcarbodiimide(DCC) enhances adenylate cyclase activity. N,N-Dicyclohexylcarbodiimide(DCC) inhibits amine accumulation. N,N-Dicyclohexylcarbodiimide(DCC) is used to prepare 3-phenylcoumarin derivatives, sulfated derivatives of purslane polysaccharides .
    N,N-Dicyclohexylcarbodiimide(DCC)
  • HY-RS23634
    Dcc Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    Dcc Rat Pre-designed siRNA Set A contains three designed siRNAs for Dcc gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Dcc Rat Pre-designed siRNA Set A
    Dcc Rat Pre-designed siRNA Set A
  • HY-RS17183
    Dcc Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA)
    Dcc Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dcc gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Dcc Mouse Pre-designed siRNA Set A
    Dcc Mouse Pre-designed siRNA Set A
  • HY-RS03571
    DCC Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    DCC Human Pre-designed siRNA Set A contains three designed siRNAs for DCC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    DCC Human Pre-designed siRNA Set A
    DCC Human Pre-designed siRNA Set A
  • HY-Y1092R
    N,N-Dicyclohexylcarbodiimide(DCC) (Standard)

    		Biochemical Assay Reagents Others
    N,N-Dicyclohexylcarbodiimide(DCC) (Standard) is the analytical standard of N,N-Dicyclohexylcarbodiimide(DCC). This product is intended for research and analytical applications. N,N-Dicyclohexylcarbodiimide(DCC) is a dehydrating and condensing agent. N,N-Dicyclohexylcarbodiimide(DCC) enhances adenylate cyclase activity. N,N-Dicyclohexylcarbodiimide(DCC) inhibits amine accumulation. N,N-Dicyclohexylcarbodiimide(DCC) is used to prepare 3-phenylcoumarin derivatives, sulfated derivatives of purslane polysaccharides .
    N,N-Dicyclohexylcarbodiimide(DCC) (Standard)
  • HY-100855
    DC_C66

    		Histone Methyltransferase Cancer
    DC_C66 is a cell-permeable, selective coactivator associated arginine methyltransferase 1 (CARM1) inhibitor with an IC50 of 1.8 μM. DC_C66 has a good selectivity for CARM1 against PRMT1 (IC50=21 μM), PRMT6 (IC50= 47μM), and PRMT5 .
    DC_C66
  • HY-163008
    Dicamba-5-aminopentanoic acid

    		Biochemical Assay Reagents Inflammation/Immunology
    Dicamba-5-aminopentanoic acid (DCc) is an immunizing and heterologous hapten, designed using the carboxylic acid group of dicamba to introduce a spacer arm for a better exposure of the herbicide's structure .
    Dicamba-5-aminopentanoic acid
  • HY-157262
    Methyl isonicotinate-(CH2)2-COOH

    		Others Infection
    Methyl isonicotinate-(CH2)2-COOH (hapten 2b) is a hapten that can be activated with NHS and DCC. Methyl isonicotinate-(CH2)2-COOH has more immunogenicity and hydrophobicity .
    Methyl isonicotinate-(CH2)2-COOH
  • HY-D2764
    Difluorocarboxyfluorescein cadaverine, 5-isomer

    		Fluorescent Dye Others
    Difluorocarboxyfluorescein cadaverine, 5-isomer is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.
    Difluorocarboxyfluorescein cadaverine, 5-isomer
  • HY-W074890
    Palmitoylglycine

    N-palmitoyl glycine

    		 Calcium Channel NO Synthase Neurological Disease Inflammation/Immunology
    Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA .
    Palmitoylglycine
  • HY-W074890R
    Palmitoylglycine (Standard)

    N-palmitoyl glycine (Standard)

    		 Calcium Channel NO Synthase Neurological Disease Inflammation/Immunology
    Palmitoylglycine (Standard) is the analytical standard of Palmitoylglycine. This product is intended for research and analytical applications. Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA[1][2][3].
    Palmitoylglycine (Standard)
  • HY-D2751
    BP Fluor 488 cadaverine

    		Fluorescent Dye Others
    BP Fluor 488 Cadaverine is a carboxyl/carbonyl reactive building block used widely to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. BP Fluor 488 dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
    BP Fluor 488 cadaverine
  • HY-D2765
    BP Fluor 405 cadaverine

    		Biochemical Assay Reagents Others
    BP Fluor 405 Cadaverine is a carbonyl-reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. Another common application for BP Fluor 405 Cadaverine is cell fixing by treatment with formaldehyde or glutaraldehyde. BP Fluor 405 is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode.
    BP Fluor 405 cadaverine
  • HY-D2772
    5-TAMRA Cadaverine

    		Biochemical Assay Reagents Others
    5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.
    5-TAMRA Cadaverine

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