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Coleonol (Standard)

" in MedChemExpress (MCE) Product Catalog:

2

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2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15371R
    Forskolin (Standard)

    Coleonol (Standard); Colforsin (Standard); HL 362 (Standard)

    		 Organoid Reference Standards Adenylate Cyclase FXR Autophagy PKC Metabolic Disease Inflammation/Immunology Endocrinology Cancer
    Forskolin (Standard) is the analytical standard of Forskolin. This product is intended for research and analytical applications. Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase . Forskolin is also an inducer of intracellular cAMP formation . Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR . Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy .
    Forskolin (Standard)
  • HY-N6927R
    Isoforskolin (Standard)

    Coleonol B (Standard)

    		 Reference Standards TNF Receptor Interleukin Related Inflammation/Immunology
    Isoforskolin (Standard) is the analytical standard of Isoforskolin. This product is intended for research and analytical applications. Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis .
    Isoforskolin (Standard)

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