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Cholesterol‑undecanoate‑glucose conjugate-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (5) ADC Linker (16) Akt (1) Amino Acid Derivatives (1) Antibiotic (4) Apoptosis (2) AUTACs (1) Autophagy (1) Bacterial (2) Biochemical Assay Reagents (6) Calcium Channel (1) CCR (1) Checkpoint Kinase (Chk) (1) CXCR (1) DNA Alkylator/Crosslinker (2) Drug Intermediate (2) Drug Metabolite (2) Drug-Linker Conjugates for ADC (13) E3 Ligase Ligand-Linker Conjugates (6) EGFR (1) Endogenous Metabolite (5) FKBP (1) FLT3 (1) Fluorescent Dye (3) GCGR (1) Glucocorticoid Receptor (2) HIV (1) HSP (1) Isotope-Labeled Compounds (1) Lactate Dehydrogenase (2) Liposome (2) Microtubule/Tubulin (2) Mitophagy (1) Nucleoside Antimetabolite/Analog (1) Parasite (2) Photosensitizer (1) PROTACs (2) Reactive Oxygen Species (ROS) (1) RET (2) SARS-CoV (1) Small Interfering RNA (siRNA) (2) STAT (1) SWI/SNF Complex (1) Target Protein Ligand-Linker Conjugates (10) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (52) Endocrinology (1) Infection (4) Inflammation/Immunology (6) Metabolic Disease (9) Neurological Disease (1)
Click Chemistry:	ADC Synthesis (2) Labeling and Fluorescence Imaging (1) DBCO (2) Azide (3) Tetrazine (2) Alkynes (2)
Oligonucleotides:	Phospholipids (1) siRNA drugs (2) siRNAs (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148067

XMT-1519 conjugate-1	Drug-Linker Conjugates for ADC	Cancer
XMT-1519 conjugate-1 (compound 31) is part of the *drug-linker conjugate* for ADC** and can be conjugated with the HER-2 monoclonal antibody Calotatug (XMT-1519) (HY-P990909) for the synthesis of ADC ^[1].

HY-159863

**Cholesterol‑undecanoate‑glucose conjugate**	Liposome	Others
Cholesterol‑undecanoate‑glucose conjugate is a glucose-based lipid conjugate used to prepare brain-targeted liposomes. Cholesterol‑undecanoate‑glucose conjugate can stably inserted into the phospholipid bilayers ^[1].

HY-167016

**Cholesterol-undecanoate-glucose conjugate**	Liposome	Others
Cholesterol-undecanoate-glucose conjugate is a cholesterol conjugate used in the synthesis of intranasal liposomal vaccines. Cholesterol-undecanoate-glucose conjugate can be used in drug delivery studies ^[1].

HY-D2261

BODIPY-cholesterol conjugate-1	Fluorescent Dye	Metabolic Disease
BODIPY-cholesterol conjugate-1 (compound 5) is a BODIPY-cholesterol conjugate. BODIPY-cholesterol conjugate-1 is a useful probe for simultaneous visualization of intracellular cholesterol pools and for monitoring cholesterol efflux from cells to extracellular acceptors ^[1]. (λex 541 nm, λem 615 nm).

HY-148202

Influenza antiviral conjugate-1	HIV	Infection
Influenza antiviral conjugate-1 (INT-2) is a HIV inhibitor, shows potent cell fusion inhibition ^[1]. Influenza antiviral conjugate-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-170854

RET Ligand-Linker Conjugate-1	Target Protein Ligand-Linker Conjugates RET	Cancer
RET Ligand-Linker Conjugate-1 is the conjugate composed of a RET ligand and a linker. RET Ligand-Linker Conjugate-1 can be used for synthesis of QZ2135 (HY-170852) ^[1].

HY-148067A

*XMT-1519 conjugate-1* TFA**	Drug-Linker Conjugates for ADC	Cancer
XMT-1519 conjugate-1 TFA (compound 31) is part of the *drug-linker conjugate* for ADC** and can be conjugated with the HER-2 monoclonal antibody Calotatug (XMT-1519) (HY-P990909) for the synthesis of ADC ^[1].

HY-132003

Wortmannin-Rapamycin Conjugate 1	Akt	Cancer
Wortmannin-Rapamycin Conjugate 1 (compound 7c) is a furan ring-opened derivative of wortmannin-rapamycin conjugate with potent antitumor activities and a fine water solubility. Wortmannin-Rapamycin Conjugate 1 can inhibit the AKT phosphorylation in the tumor and can be used for cancer research ^[1].

HY-173370

MAGL Ligand-Linker Conjugate 1	E3 Ligase Ligand-Linker Conjugates	Others
MAGL Ligand-Linker Conjugate 1 is a conjugate of the MAGL ligand and the linker. MAGL Ligand-Linker Conjugate 1 can be used for synthesis of PROTAC degrader PROTAC MAGL degrader-1 (HY-173369) ^[1].

HY-151559

Zn-DPA-maytansinoid conjugate 1	Checkpoint Kinase (Chk) STAT CXCR CCR	Cancer
Zn-DPA-maytansinoid conjugate 1 is a small molecule-based maytansinoid conjugate targeting immune checkpoint. Zn-DPA-maytansinoid conjugate 1 induces lasting regression of tumor growth and rejuvenates tumor microenvironment (TME) to an "inflamed hot tumor" ^[1].

HY-44148

FAK ligand-Linker Conjugate 1	Target Protein Ligand-Linker Conjugates	Cancer
FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation ^[1].

HY-161341

β-Glucuronidase responsive conjugate 1	Photosensitizer	Cancer
β-Glucuronidase responsive conjugate 1 (compound 3) is a well-balanced photosensitizer which has photodynamic activity. β-Glucuronidase responsive conjugate 1 inhibits T-24 cell viability and growth with an IC₅₀ of 0.2 μM. β-Glucuronidase responsive conjugate 1 can used to study bladder cancers ^[1].

HY-173470

MTP3 Ligand-linker Conjugate 1	E3 Ligase Ligand-Linker Conjugates	Cancer
MTP3 Ligand-linker Conjugate 1 is a conjugate of the MTP3 ligand and the linker. MTP3 Ligand-linker Conjugate 1 can be used for synthesis of PROTAC MTP3 degrade-1 (HY-173467) ^[1].

HY-170987

FKBP12 Ligand-Linker Conjugate 1	Target Protein Ligand-Linker Conjugates FKBP	Cancer
FKBP12 Ligand-Linker Conjugate 1 is the conjugate composed of a target protein ligand for FKBP12 and a linker. FKBP12 Ligand-Linker Conjugate 1 can be used for synthesis of PROTAC degrader MC-25B (HY-170983) ^[1].

HY-132943

BRD4 ligand-Linker Conjugate 1	Target Protein Ligand-Linker Conjugates	Cancer
BRD4 ligand-Linker Conjugate 1 is a target protein ligand-linker conjugate that can be used in the synthesis of PROTACs.

HY-170769

FLT3 Ligand-Linker Conjugate 1	Target Protein Ligand-Linker Conjugates FLT3	Cancer
FLT3 Ligand-Linker Conjugate 1 (compound 7) contains the FLT3 ligand and a PROTAC linker, which can recruit the E3 ligase VHL. FLT3 Ligand-Linker Conjugate 1 can be used to synthesize the PROTAC RSS0680 (HY-148062). PROTAC RSS0680 is a bifunctional compound that targets protein degradation of kinases ^[1].

HY-129775

K-Ras ligand-Linker Conjugate 1	Target Protein Ligand-Linker Conjugates	Cancer
K-Ras ligand-Linker Conjugate 1 incorporates a ligand for K-Ras, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 1 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells ^[1].

HY-173137

KDM4 Ligand-Linker Conjugate 1	Target Protein Ligand-Linker Conjugates	Others
KDM4 Ligand-Linker Conjugate 1 is a conjugate of a KDM4 target protein ligand and a linker, and can be used for the synthesis of PROTAC KDM4 degrader-1 (HY-173135) ^[1].

HY-168295

p62-ZZ Ligand-Linker Conjugate 1	E3 Ligase Ligand-Linker Conjugates Autophagy	Cancer
p62-ZZ Ligand-Linker Conjugate 1 is a p62-ZZ domain ligand-linker conjugate. p62-ZZ Ligand-Linker Conjugate 1 can be used to synthesize AUTOTAC VinclozolinM2-2204 (HY-161741) ^[1].

HY-132943A

*BRD4 ligand-Linker Conjugate 1* TFA**	Target Protein Ligand-Linker Conjugates	Cancer
BRD4 ligand-Linker Conjugate 1 TFA (compound 106-1) is a target protein ligand-linker conjugate that can be used in the synthesis of PROTACs ^[1] .

HY-159543

(S,R,S)-AHPC-CO-Ph-Ph-CHO	E3 Ligase Ligand-Linker Conjugates	Cancer
SMARCA2-ligand-Linker Conjugate-1 is an E3 ligase ligand-linker conjugate.

HY-170828

SMD-1087	PROTACs SWI/SNF Complex	Others
SMD-1087 is a PROTAC that selectively targets SMARCA2 (DC₅₀=8 nM, D_max=89%) and SMARCA4 with a DC₅₀ of 1 μM. SMD-1087 consists of the E3 ligase ligand (S,R,S)-AHPC-Me (blue part) (HY-112078), the target protein ligand SMI-1074 (red part) (HY-170817), and the PROTAC linker (1r,4r)-tert-Butyl 4-(bromomethyl)cyclohexanecarboxylate (black part) (HY-W890392). Among them, its target protein ligand + Linker part corresponds to SMARCA2 Ligand-Linker Conjugate-1 (HY-170829) ^[1].

HY-170852

QZ2135	PROTACs RET	Cancer
QZ2135 (compound 20) is a RET-targeted PROTAC degrader with in vivo antitumor properties in a Ba/F3-KIF5B-RET-G810C xenograft mouse model. The degradation activities of QZ2135 targeting KIF5B-RET have DC₅₀ values of 4.7 nM (WT), 17.2 nM (V804M), and 73.8 nM (G810C), respectively. QZ2135 is composed of a target protein ligand (red part) RET ligand-3 (HY-170853), an E3 ligase ligand (blue part) Lenalidomide-F (HY-W039233), and a PROTAC Linker (black part) 7-Iodohept-1-yne (HY-W587352), in which the target protein ligand + linker form a conjugate RET Ligand-Linker Conjugate-1 (HY-170854) ^[1].

HY-P10906

Talovirtide	Biochemical Assay Reagents	Others
Talovirtide is a peptide containing L-valyl ^[1].

HY-P10872

P315V3	SARS-CoV	Infection
P315V3 is an pan inhibitor for coronavirus, that inhibits SARS-CoV-2 prototypePT, Delta, BA.1 and BA.4 strain with IC₅₀s of 10.9, 8.9, 8.6, and 2.7 nM. P315V3 exhibits cytotoxicity in Vero cell with CC₅₀ of 4.3 μM. P315V3 exhibits anti-infectious efficacy in mouse models ^[1].

HY-P2424

Cholecystokinin-J CCK-J	Calcium Channel	Others
Cholecystokinin-J (CCK-J), a cholecystokinin, stimulates Ca ²⁺ release ^[1].

HY-128820

cIAP1 Ligand-Linker Conjugates 1 E3 ligase Ligand-Linker conjugates 41	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 1 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 1 can be used to design SNIPERs ^[1].

HY-113293A

Estrone sulfate potassium 1 Publications Verification	Endogenous Metabolite	Endocrinology Cancer
Estrone sulfate potassium is a natural endogenous steroid and is an estrogen ester and conjugate .

HY-130270

AhR Ligand-Linker Conjugates 1 E3 Ligase Ligand-Linker conjugates 57	E3 Ligase Ligand-Linker Conjugates	Cancer
AhR Ligand-Linker Conjugates 1 (E3 Ligase Ligand-Linker Conjugates 57) incorporates an IAP ligand for the E3 ubiquitin ligase, and a SNIPER linker. AhR Ligand-Linker Conjugates 1 can be used to design SNIPER ^[1].

HY-130099

Ald-Ph-amido-PEG2	ADC Linker	Cancer
Ald-Ph-amido-PEG2 is a noncleavable ADC linker for antibody-drug conjugate .

HY-170460

α-D-Galactopyranosylphenyl isothiocyanate	Biochemical Assay Reagents	Others
α-D-Galactopyranosylphenyl isothiocyanate can be used to synthesis Galactosylated a-CDE conjugate .

HY-P4198

Fmoc-N(Me)-Sar10 Fmoc-Sar10	Biochemical Assay Reagents	Others
Fmoc-N(Me)-Sar10 can be used for synthesis of peptide ligand-agent conjugates .

HY-141664

PPA	ADC Linker	Cancer
PPA is an ADC linker (US20060073528A1). PPA can be used for making antibody-drug conjugate .

HY-P3669

Gly-Gly-Phe-Gly	Drug Intermediate	Cancer
Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates .

HY-159162

7-(2-Aminoethyl)camptothecin 7CPT	Drug Intermediate	Others
7-(2-Aminoethyl)camptothecin (7CPT) is a derivative of camptothecin that can be used to prepare TFO-CPT conjugates .

HY-147164

MC-Gly-Gly-Phe-Gly-PAB-PNP	ADC Linker	Cancer
MC-Gly-Gly-Phe-Gly-PAB-PNP is a linker for synthesis anti-human EGFR antibody agent conjugate .

HY-W777199

Tianeptine metabolite MC5 sodium salt	Drug Metabolite	Others
Tianeptine metabolite MC5 sodium salt is a major active metabolite of tianeptine. Tianeptine and MC5 metabolite are eliminated with bile as glucuronide and glutamine conjugates .

HY-130499

ERRα Ligand-Linker Conjugates 1	Target Protein Ligand-Linker Conjugates	Cancer
ERRα Ligand-Linker Conjugates 1 incorporates a ligand for estrogen-related receptor alpha (ERRα), and a PROTAC linker, which recruit E3 ligases MDM2. ERRα Ligand-Linker Conjugates 1 can be used in the synthesis of a series of PROTACs, such as PROTAC ERRalpha Degrader-1 (HY-128838). PROTAC ERRalpha Degrader-1 is an ERRα degrader ^[1].

HY-164794

Pyridyl disulfide-Dexamethasone	Glucocorticoid Receptor	Inflammation/Immunology
Pyridyl disulfide-Dexamethasone is a Dexamethasone (HY-14648) modified with pyridyl disulfide, which can be used for the synthesis of targeted peptide steroid conjugates .

HY-41049

NSC 135130	ADC Linker	Cancer
NSC 135130 (compound 11a) is a BOC-protected ADC linker that can be linked to tubulin-targeting inhibitors.Can be used to synthesize drug conjugates .

HY-48668

AcLys-PABC-VC-Aur0101 intermediate-1	ADC Linker	Cancer
AcLys-PABC-VC-Aur0101 intermediate-1 is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate .

HY-128926

SPP N-succinimidyl 4-(2-pyridyldithio) pentanoate	ADC Linker	Cancer
SPP (N-succinimidyl 4-(2-pyridyldithio) pentanoate) is a cleavable disulfide linker, can be used to form cytotoxic compound- linker conjugate .

HY-153958

PDS-MMAE	Drug-Linker Conjugates for ADC	Cancer
PDS-MMAE (Compound 5’) is a modified MMAE (HY-15162). PDS-MMAE can be used for preparation of neurotensin receptor binding conjugates .

HY-151714

Biotin-MeTz	ADC Linker	Others
Biotin-MeTz shiyi is a click chemistry reagent with a terminal methyltetrazine group. Biotin-MeTz shiyi, as a biotin derivative, can be used for the preparation of biotinylated conjugates .

HY-157198

Dinotefuran-NHCO-propionic acid	Biochemical Assay Reagents	Inflammation/Immunology
Dinotefuran-NHCO-propionic acid (4) is an antigen. Dinotefuran-NHCO-propionic acid can couple BSA and OVA to obtain the immunogen and the coating antigen (hapten-OVA conjugate) .

HY-150074

STING agonist-18	ADC Cytotoxin	Cancer
STING agonist-18 (compound 1a) can be used for synthesis of antibody-drug conjugates (ADCs), such Trastuzumab (HY-P9907) conjugate .

HY-147225

TSPO Ligand-Linker Conjugates 1	AUTACs Mitophagy	Neurological Disease Metabolic Disease Cancer
TSPO Ligand-Linker Conjugates 1 contains a ligand for translocator protein (TSPO) and a linker, which is used for the synthesis of mitochondria-targeting autophagy-targeting chimera (AUTAC). AUTAC can bind the TSPO on the outer mitochondrial membrane (OMM) of mitochondria and degrades impaired mitochondria and proteins via mitophagy, and improves mitochondrial activity. TSPO Ligand-Linker Conjugates 1 can be used in mitochondrial dysfunction related research, including neurodegenerative diseases, cancer, and diabetes ^[1].

HY-150074A

STING agonist-18 diTFA	ADC Cytotoxin	Cancer
STING agonist-18 diTFA (compound 1a) can be used for synthesis of antibody-drug conjugates (ADCs), such Trastuzumab (HY-P9907) conjugate .

HY-126493A

(R)-DM4-SPDP	Drug-Linker Conjugates for ADC	Others
(R)-DM4-SPDP is a conjugate made up of the linker SPDP and the toxic molecule DM4, and it can be used to prepare antibody-drug conjugates .

HY-128871

VCP-Eribulin	Drug-Linker Conjugates for ADC	Cancer
VCP-Eribulin consists the ADCs linker (VCP) and Eribulin ^[1]. Eribulin is a mechanistically unique microtubule inhibitor for cancer . VCP-Eribulin is an Eribulin-based agent for antibody conjugates .

Cat. No.	Product Name	Type

HY-15938

5-FAM SE	Fluorescent Dyes/Probes
5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates .

HY-45672G

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)	Fluorescent Dye
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .

Cat. No.	Product Name	Type

HY-167016

**Cholesterol-undecanoate-glucose conjugate**	Drug Delivery
Cholesterol-undecanoate-glucose conjugate is a cholesterol conjugate used in the synthesis of intranasal liposomal vaccines. Cholesterol-undecanoate-glucose conjugate can be used in drug delivery studies ^[1].

HY-170460

α-D-Galactopyranosylphenyl isothiocyanate	Carbohydrates
α-D-Galactopyranosylphenyl isothiocyanate can be used to synthesis Galactosylated a-CDE conjugate .

HY-45672G

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)	Biochemical Assay Reagents
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .

Cat. No.	Product Name	Target	Research Area

HY-P4198

Fmoc-N(Me)-Sar10 Fmoc-Sar10	Biochemical Assay Reagents	Others
Fmoc-N(Me)-Sar10 can be used for synthesis of peptide ligand-agent conjugates .

HY-P3669

Gly-Gly-Phe-Gly	Drug Intermediate	Cancer
Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates .

HY-P4166

Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar	Peptides	Cancer
Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar is a decapeptide. Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar can be used to preparation of antibody-drug conjugate .

HY-P3361A

IDR-1018 acetate	Parasite Bacterial Antibiotic	Infection Inflammation/Immunology
IDR-1018 acetate is an innate defense regulator conjugate, with MICs of 16 μg/mL for MRSA USA300 LAC, MRSA SAP 0017 and S. epidermidis ATCC14990. IDR-1018 acetate can be used to synthesis V-IDR1018 (vancomycin-innate defense regulator conjugate) .

HY-P10736A

AMG133 peptide payload TFA	GCGR	Metabolic Disease
AMG133 peptide payload TFA is the TFA salt form of AMG133 peptide payload (HY-P10736). AMG133 peptide payload TFA is a *GLP-1* agonist that can be used for synthesis of Maridebart cafraglutide (AMG133) (HY-164535) as a peptide linker conjugate .

HY-P10906

Talovirtide	Biochemical Assay Reagents	Others
Talovirtide is a peptide containing L-valyl ^[1].

HY-P10872

P315V3	SARS-CoV	Infection
P315V3 is an pan inhibitor for coronavirus, that inhibits SARS-CoV-2 prototypePT, Delta, BA.1 and BA.4 strain with IC₅₀s of 10.9, 8.9, 8.6, and 2.7 nM. P315V3 exhibits cytotoxicity in Vero cell with CC₅₀ of 4.3 μM. P315V3 exhibits anti-infectious efficacy in mouse models ^[1].

HY-P2424

Cholecystokinin-J CCK-J	Calcium Channel	Others
Cholecystokinin-J (CCK-J), a cholecystokinin, stimulates Ca ²⁺ release ^[1].

HY-164166

Fmoc-Sar-Sar-Sar-OH	Biochemical Assay Reagents	Others
Fmoc-Sar-Sar-Sar-OH is a small molecule polypeptide composed of four sarcosine residues, in which the N-terminus of the peptide chain is protected by Fmoc. Fmoc-Sar-Sar-Sar-OH can be used for peptide synthesis or synthesis of drug-peptide ligand conjugates .

HY-P3361

IDR-1018	Parasite Bacterial Antibiotic	Infection Inflammation/Immunology
IDR-1018 is an innate defense regulator conjugate, with MICs of 16 μg/mL for MRSA USA300 LAC, MRSA SAP 0017 and S. epidermidis ATCC14990. IDR-1018 can be used to synthesis V-IDR1018 (vancomycin-innate defense regulator conjugate) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113293A

Estrone sulfate potassium 1 Publications Verification	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	Endogenous Metabolite
Estrone sulfate potassium is a natural endogenous steroid and is an estrogen ester and conjugate .

HY-112942A

CMP-Sialic acid sodium salt 1 Publications Verification CMP-Neu5Ac sodium salt	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-112942

CMP-Sialic acid CMP-Neu5Ac	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CMP-Sialic acid (CMP-Neu5Ac) is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid provides a substrate for Golgi sialyltransferases. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-112942AR

CMP-Sialic acid sodium salt (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
CMP-Sialic acid (sodium salt) (Standard) is the analytical standard of CMP-Sialic acid (sodium salt). This product is intended for research and analytical applications. CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

Cat. No.	Product Name	Chemical Structure

HY-18569S

3-Indoleacetic acid-d5 1 Publications Verification
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates .

Cat. No.	Product Name		Classification

HY-151741

Biotin-PEG4-MeTz		Labeling and Fluorescence Imaging Tetrazine
Biotin-PEG4-MeTz is a click chemistry reagent containing a terminal methyltetrazine group that reacts with trans-cyclooctene. Biotin-PEG4-MeTz can be used for the preparation of biotinylated conjugates .

HY-151667

Biotin-C5-Azide DecarboxyBiotin-N3		Azide
Biotin-C5-Azide (DecarboxyBiotin-N3) is a biotin reagent and can be used to prepare biotinylated conjugates . Biotin-C5-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-126690

DBCO-(PEG2-VC-PAB-MMAE)2		DBCO
DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody agent conjugate . DBCO-(PEG2-VC-PAB-MMAE)2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-147363

DIBAC-GGFG-NH2CH2-Dxd		DBCO ADC Synthesis
DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin (HY-16560) derivative, is a linker-payload of protein-agent conjugates . Dxd (HY-13631D) can be used as a payload for the antibody-coupling drug ADC (DS-8201a).DIBAC-GGFG-NH2CH2-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups ^[1] .

HY-148202

Influenza antiviral conjugate-1		Alkynes
Influenza antiviral conjugate-1 (INT-2) is a HIV inhibitor, shows potent cell fusion inhibition ^[1]. Influenza antiviral conjugate-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151714

Biotin-MeTz		Tetrazine
Biotin-MeTz shiyi is a click chemistry reagent with a terminal methyltetrazine group. Biotin-MeTz shiyi, as a biotin derivative, can be used for the preparation of biotinylated conjugates .

HY-151740

4-Pentynoyl-Val-Ala-PAB-PNP		ADC Synthesis Alkynes
4-Pentynoyl-Val-Ala-PAB-PNP is a cleavable ADC linker, that has been used to synthesis cryptophycin conjugates . 4-Pentynoyl-Val-Ala-PAB-PNP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-153486

N3-VC-PAB-PNP		Azide
N3-VC-PAB-PNP is the intermediate of bicyclic peptide ligand STING conjugates . N3-VC-PAB-PNP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151791

(S,R,S)-AHPC-C6-PEG3-butyl-N3		Azide
(S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. (S,R,S)-AHPC-C6-PEG3-butyl-N3 serves as crosslinker-E3 ligase ligand conjugate, Click reactive protein degrader building block for PROTAC research, Template for synthesis of targeted protein degrader, VH032 conjugate . (S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-132606A

Nedosiran sodium DCR-PHXC sodium		siRNAs siRNA drugs
Nedosiran (DCR-PHXC) sodium is an RNA interference (RNAi) targeting lactate dehydrogenase (LDH). Nedosiran sodium represents an impactful potential therapeutic for primary hyperoxaluria (PH) with end-stage renal disease (ESRD). Nedosiran sodium is a GalNAc-dsRNA conjugate .

HY-132606

Nedosiran DCR-PHXC		siRNAs siRNA drugs
Nedosiran (DCR-PHXC) is an RNA interference (RNAi) targeting lactate dehydrogenase (LDH). Nedosiran represents an impactful potential therapeutic for primary hyperoxaluria (PH) with end-stage renal disease (ESRD). Nedosiran is a GalNAc-dsRNA conjugate .

HY-158710

1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc		Phospholipids
1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc is a phospholipid-porphyrin conjugate. 1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc can be utilized in photodynamic therapy research ^[1].

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Cholesterol‑undecanoate‑glucose conjugate-1

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Fluorescent Dye

Biochemical Assay Reagents

Peptides

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Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

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