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CYP4A2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	COX (2) Cytochrome P450 (10) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (3) Metabolic Disease (5)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (2) siRNAs (2)

Inhibitors & Agonists

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-119647

PPOH	COX Cytochrome P450	Others
PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC₅₀ values of 22 μM and 6.5 μM, respectively . PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-124527

HET0016 2 Publications Verification	Cytochrome P450	Cardiovascular Disease Cancer
HET0016 is a potent and selective 20-hydroxyeicosatetraenoic acid (20-HETE) synthase inhibitor, with IC₅₀ values of 17.7 nM, 12.1 nM and 20.6 nM for recombinant CYP4A1-, CYP4A2- and CYP4A3-catalyzed 20-HETE synthesis, respectively. HET0016 also is a selective CYP450 inhibitor, which has been shown to inhibit angiogenesis and tumor growth .

HY-151809

*CYP4A11/CYP4F2-IN-1*	Cytochrome P450	Metabolic Disease
CYP4A11/CYP4F2-IN-1 is a potent dual inhibitor of cytochrome P450 (CYP) 4A11 and *CYP4F2, with IC₅₀s of 19 nM and 17 nM, respectively. CYP4A11/CYP4F2*-IN-1 has potential for the research of renal diseases .

HY-151810

TP0472993	Cytochrome P450	Metabolic Disease
CYP4A11/CYP4F2-IN-2 is a potent and orally active dual inhibitor of cytochrome P450 (CYP) 4A11 and *CYP4F2, with IC₅₀s of 140 nM and 40 nM, respectively. CYP4A11/CYP4F2*-IN-2 has potential for the research of renal diseases .

HY-119647R

PPOH (Standard)	COX Cytochrome P450	Others
PPOH (Standard) is the analytical standard of PPOH. This product is intended for research and analytical applications. PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC50 values of 22 μM and 6.5 μM, respectively . PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-124527R

HET0016 (Standard)	Cytochrome P450	Cardiovascular Disease Cancer
HET0016 (Standard) is the analytical standard of HET0016. This product is intended for research and analytical applications. HET0016 is a potent and selective 20-hydroxyeicosatetraenoic acid (20-HETE) synthase inhibitor, with IC50 values of 17.7 nM, 12.1 nM and 20.6 nM for recombinant CYP4A1-, CYP4A2- and CYP4A3-catalyzed 20-HETE synthesis, respectively. HET0016 also is a selective CYP450 inhibitor, which has been shown to inhibit angiogenesis and tumor growth .

HY-E70487

*Human CYP4F2,Low-Reductase+b5*	Cytochrome P450	Metabolic Disease
Human CYP4F2, Low-Reductase+b5, a recombinant CYP4F2, is a member of the CYP enzyme family. CYP4F2 catalyzes (helps speed up) chemical reactions inside cells .

HY-149770

*CYP4A11/CYP4F2-IN-2*	Cytochrome P450	Metabolic Disease
CYP4A11/CYP4F2-IN-2 (compound 15) is an orally available inhibitor of CYP4A11/4F2 with IC₅₀s of 120 nM and 220 nM, respectively. CYP4A11/CYP4F2-IN-2 inhibits 20-HETE production in rat kidney and has potential inhibitory effects on diabetic nephropathy and autosomal dominant polycystic kidney disease .

HY-RS03480

CYP4F2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CYP4F2 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP4F2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CYP4F2 Human Pre-designed siRNA Set A CYP4F2 Human Pre-designed siRNA Set A

HY-RS03483

CYP4V2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CYP4V2 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP4V2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CYP4V2 Human Pre-designed siRNA Set A CYP4V2 Human Pre-designed siRNA Set A

HY-W472509

11-HETE 11-Hydroxy-5,8,12,14-eicosatetraenoic acid	Cytochrome P450	Cardiovascular Disease
11-HETE (11-Hydroxy-5,8,12,14-eicosatetraenoic acid) is the activator for cytochrome P450. 11-HETE upregulates the mRNA expressions of CYP1B1, CYP1A1, CYP4A11, CYP4F11, and CYP4F2, induces cell hypertrophy in RL-14 cell, and exhibits potential to be used in cardiovascular diseases .

HY-156876

20-HETE inhibitor-2	Cytochrome P450	Metabolic Disease
20-HETE inhibitor-2 is an orally active 20-HETE inhibitor. 20-HETE inhibitor-2 can inhibit the activities of *CYP4F2* and CYP4A11, thereby suppressing the production of 20-HETE. 20-HETE inhibitor-2 has the effect of improving blood glucose and can be used for the research of various diseases related to 20-HETE such as obesity .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82342

	Cytochrome P450 4A Antibody (YA2087) cytochrome P450 family 4 subfamily A member 11; CP4Y; CYP4A2; CYP4AII; CYPIVA11	WB, IHC-P, IP	Human, Mouse, Rat
	Cytochrome P450 4A Antibody (YA2087) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2087), targeting Cytochrome P450 4A, with a predicted molecular weight of 59 kDa (observed band size: 50 kDa). Cytochrome P450 4A Antibody (YA2087) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

HY-P83696

	Cytochrome P450 4A/CYP4A11 Antibody (YA3431) cytochrome P450 family 4 subfamily A member 11; CP4Y; CYP4A2; CYP4AII; CYPIVA11	WB, IHC-P, IP	Human, Mouse, Rat
	CYP4A11 Antibody is an unconjugated, approximately 59 kDa, rabbit-derived, anti-CYP4A11 monoclonal antibody. CYP4A11 Antibody can be used for: WB,IHC-P,IP expriments in Human, Mouse,Rat background without labeling.

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Cat. No.	Product Name		Classification

HY-119647

PPOH		Alkynes
PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC₅₀ values of 22 μM and 6.5 μM, respectively . PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

CYP4F2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CYP4F2 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP4F2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CYP4V2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CYP4V2 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP4V2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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