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Results for "

CTP inhibitor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Akt (3) Apoptosis (2) DNA/RNA Synthesis (9) Drug Metabolite (1) HCV (2) HIV (4) HSV (1) Influenza Virus (1) Isotope-Labeled Compounds (2) Mitochondrial Metabolism (1) Necroptosis (1) NF-κB (1) Nucleoside Antimetabolite/Analog (2) P2X Receptor (1) Parasite (3) Serotonin Transporter (1)
By Research Areas:	Cancer (10) Infection (7) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (1)
Oligonucleotides:	Nucleotide Analogs (2) Cytidine Nucleotide (2)

Inhibitors & Agonists

Peptides

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101998

**CTP inhibitor**	Mitochondrial Metabolism	Metabolic Disease
CTP inhibitor (Compound 792949) is a potent and selective *CTP* inhibitor. CTP inhibitor inhibits the plasma membrane citrate transporter (PMCT) .

HY-152149

CTP Synthetase-IN-1	DNA/RNA Synthesis	Inflammation/Immunology
CTP Synthetase-IN-1 is a potent, orally active cytidine 5'-triphosphate synthetase (CTPS) inhibitor with IC₅₀s of 32 nM and 18 nM for human CTPS1 and human CTPS2, respectively. CTP Synthetase-IN-1 has anti-inflammatory effects .

HY-157746

CTPS1-IN-1	DNA/RNA Synthesis	Inflammation/Immunology Cancer
CTPS1-IN-1 (compound R80) is a *CTPS1* inhibitor. CTPS1-IN-1 has the potential to research cancer (such as promoting vascular injury or surgical recovery) and immune system diseases (such as rejection of transplanted cells and tissues, transplant-related diseases or disorders, allergies, and autoimmune diseases) .

HY-115740A

Cytarabine triphosphate trisodium Ara-CTP trisodium	DNA/RNA Synthesis	Cancer
Cytarabine triphosphate (Ara-CTP) trisodiu, an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate trisodiu levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine .

HY-P10081

CTP-NBD	NF-κB	Inflammation/Immunology
CTP-NBD is a cell permeable specific NFκB peptide inhibitor. CTP-NBD could be used in colitis study

HY-171587A

3′-Deoxy CTP trisodium	HCV	Infection
3′-Deoxy CTP trisodium is the sodium salt form of 3′-Deoxy CTP (HY-171587). 3′-Deoxy CTP trisodium is a nucleotide analogue and a mandatory chain terminator. 3′-Deoxy CTP trisodium can cause chain termination by lacking the 3′-hydroxyl group, inhibiting the RNA synthesis activity of HCV nonstructural protein (NS5B) polymerase and blocking viral replication. 3′-Deoxy CTP trisodium can be used to study the chain termination mechanism of HCV polymerase and the development of antiviral drugs .

HY-171578

3′-Amino-2′,3′-dideoxy-CTP	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Others
3′-Amino-2′,3′-dideoxy-CTP is an analogue of nucleoside triphosphate. 3′-Amino-2′,3′-dideoxy-CTP can selectively inhibit DNA polymerase β .

HY-171574

3′-Azido-2′,3′-dideoxy-CTP AZddCTP	HIV DNA/RNA Synthesis	Infection
3′-Azido-2′,3′-dideoxy-CTP (AZddCTP) is a cytidine analog containing a 3-azido group. As a chain terminator, 3′-Azido-2′,3′-dideoxy-CTP can be incorporated into the nascent DNA chain by HIV reverse transcriptase. 3′-Azido-2′,3′-dideoxy-CTP terminates DNA synthesis due to the lack of a 3'-hydroxyl group, thereby inhibiting viral replication. 3′-Azido-2′,3′-dideoxy-CTP has IC₅₀ values of 15.6 μM and 160.8 μM for WT HIV and AZT ^R HIV. 3′-Azido-2′,3′-dideoxy-CTP has antiviral activity .

HY-171587

3′-Deoxy CTP	HCV	Infection
3′-Deoxy CTP is a nucleotide analogue and a mandatory chain terminator. 3′-Deoxy CTP can cause chain termination by lacking the 3′-hydroxyl group, inhibiting the RNA synthesis activity of HCV nonstructural protein (NS5B) polymerase and blocking viral replication. 3′-Deoxy CTP can be used to study the chain termination mechanism of HCV polymerase and the development of antiviral drugs .

HY-115740

Cytarabine triphosphate Ara-CTP	DNA/RNA Synthesis	Cancer
Cytarabine triphosphate (Ara-CTP), an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine .

HY-13685

Miltefosine 10+ Cited Publications HePC; Hexadecyl phosphocholine	Akt HIV Parasite	Infection Cancer
Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity . Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT) .

HY-157783

Dencatistat	DNA/RNA Synthesis	Inflammation/Immunology Cancer
Dencatistat (P115) is an inhibitor of Cytidine Triphosphate Synthase 1 (CTPS1) with an IC₅₀ value of ≤ 0.1 μM. Dencatistat can be used for research on cancer (such as leukemia and lymphoma), inflammatory skin diseases (such as psoriasis), or multiple sclerosis .

HY-106777

Cyclopentenylcytosine 1 Publications Verification CPEC; NSC 375575	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Apoptosis Necroptosis Influenza Virus HSV	Infection Cancer
Cyclopentenylcytosine (CPEC), a carbocyclic nucleoside analog of cytosine, is a potent inhibitor of CTP synthetase and causes depletion of CTP and dCTP pools. Cyclopentenylcytosine shows broad-spectrum (both DNA and RNA viruses) antiviral activity. Cyclopentenyl cytosine increases Gemcitabine (HY-17026) radiosensitisation in human pancreatic cancer cells. Cyclopentenylcytosine shows effective antiviral activity in the Ad5/NZW rabbit ocular replication model and shows anti-tumor activity in various tumor xenografts model. Cyclopentenylcytosine can be used for the study of infection and cancer .

HY-176891

Cyslopentenyl cytosine triphosphoric	Drug Metabolite DNA/RNA Synthesis	Cancer
Cyslopentenyl cytosine triphosphoric is an active metabolite of the antitumor nucleoside analogue cyclopentenyl cytosine (CPEC) within cells. Cyslopentenyl cytosine triphosphoric can inhibit CTP synthetase and deplete the pools of cytidine nucleotides. Cyslopentenyl cytosine triphosphoric can be used for the research of cancer, such as leukemia .

HY-13685R

Miltefosine (Standard)	Akt HIV Parasite	Infection Cancer
Miltefosine (Standard) is the analytical standard of Miltefosine. This product is intended for research and analytical applications. Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity . Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT) .

HY-13685S1

Miltefosine-d4 HePC-d₄; Hexadecyl phosphocholine-d₄	Isotope-Labeled Compounds Akt Parasite HIV	Infection Cancer
Miltefosine-d₄ (HePC-d₄) is deuterium labeled Miltefosine. Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity . Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT) .

HY-111124

Paroxetine-d2 CTP 347; BRL29060-d₂	Isotope-Labeled Compounds Serotonin Transporter Adrenergic Receptor P2X Receptor Apoptosis	Neurological Disease Cancer
Paroxetine-d₂ (CTP 347) is a deuterium labeled Paroxetine (HY-122272). Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs). Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches .

Cat. No.	Product Name	Target	Research Area

HY-P10081

CTP-NBD	NF-κB	Inflammation/Immunology
CTP-NBD is a cell permeable specific NFκB peptide inhibitor. CTP-NBD could be used in colitis study

Cat. No.	Product Name	Chemical Structure

HY-13685S1

Miltefosine-d4
Miltefosine-d₄ (HePC-d₄) is deuterium labeled Miltefosine. Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity . Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT) .

HY-111124

Paroxetine-d2
Paroxetine-d₂ (CTP 347) is a deuterium labeled Paroxetine (HY-122272). Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs). Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches .

Paroxetine-d2

Paroxetine-d₂ (CTP 347) is a deuterium labeled Paroxetine (HY-122272). Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs). Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches .

Cat. No.	Product Name		Classification

HY-171578

3′-Amino-2′,3′-dideoxy-CTP		Nucleotide Analogs Cytidine Nucleotide
3′-Amino-2′,3′-dideoxy-CTP is an analogue of nucleoside triphosphate. 3′-Amino-2′,3′-dideoxy-CTP can selectively inhibit DNA polymerase β .

HY-171574

3′-Azido-2′,3′-dideoxy-CTP AZddCTP		Nucleotide Analogs Cytidine Nucleotide
3′-Azido-2′,3′-dideoxy-CTP (AZddCTP) is a cytidine analog containing a 3-azido group. As a chain terminator, 3′-Azido-2′,3′-dideoxy-CTP can be incorporated into the nascent DNA chain by HIV reverse transcriptase. 3′-Azido-2′,3′-dideoxy-CTP terminates DNA synthesis due to the lack of a 3'-hydroxyl group, thereby inhibiting viral replication. 3′-Azido-2′,3′-dideoxy-CTP has IC₅₀ values of 15.6 μM and 160.8 μM for WT HIV and AZT ^R HIV. 3′-Azido-2′,3′-dideoxy-CTP has antiviral activity .

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