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Results for "

CTGF

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Casein Kinase (1) ERK (1) p38 MAPK (1) Ras (1) ROCK (1) Small Interfering RNA (siRNA) (3) Survivin (1) TAM Receptor (1) Wnt (1) YAP (8)
By Research Areas:	Cancer (10) Cardiovascular Disease (1) Inflammation/Immunology (1) Neurological Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99288

FG-3019 Pamrevlumab; Anti-Human CTGF Recombinant Antibody	Apoptosis	Cancer
FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF) .

HY-155310

AF-2112	YAP	Cancer
AF-2112 is a Flufenamic acid-derived TEAD inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2.

HY-155309

LM-41	YAP	Cancer
LM-41 is a Flufenamic acid-derived TEAD inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2. LM-41 inhibits migration of human MDA-MB-231 breast cancer cells .

HY-120006A

(rel)-AR234960 1 Publications Verification	ERK	Cardiovascular Disease
(rel)-AR234960 is a selective and competitive agonist of the G protein-coupled receptor MAS. (rel)-AR234960 binds to the MAS receptor to activate the downstream ERK1/2 signaling pathway, inducing the expression of connective tissue growth factor (CTGF) and its downstream collagen subtype genes (such as COL1A1, COL3A1). (rel)-AR234960 promotes collagen synthesis in cardiac fibroblasts through the *MAS-ERK1/2-CTGF* pathway and aggravates extracellular matrix remodeling. (rel)-AR234960's in vitro effect can be blocked by the MAS inverse agonist AR244555 and MEK1 inhibitor. (rel)-AR234960 regulates the expression of cardiac fibrosis-related genes and can be used in the study of heart failure .

HY-130011

CCG-232964	ROCK Ras	Neurological Disease Cancer
CCG-232964 is an orally active inhibitor of Rho/MRTF/SRF. CCG-232964 inhibits LPA-induced CTGF gene expression .

HY-RS23610

Ccn2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ccn2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccn2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ccn2 Rat Pre-designed siRNA Set A Ccn2 Rat Pre-designed siRNA Set A

HY-162012

HC-258	YAP	Cancer
HC-258 (compound 26) binds with the cysteine in TEAD’s PA pocket. HC-258 reduces the CTGF, CYR61, AXL, and NF2 transcript levels and inhibits the migration of MDA-MB-231 breast cancer cells .

HY-168704

YAP/TAZ-TEAD-IN-2	YAP TAM Receptor Survivin	Cancer
YAP/TAZ-TEAD-IN-2 (Compound 51) is a YAP/TAZ-TEAD inhibitor that inhibits the interaction between YAP/TAZ and TEAD. YAP/TAZ-TEAD-IN-2 suppresses the transcriptional activity of TEAD, with an IC₅₀ of 1.2 nM. YAP/TAZ-TEAD-IN-2 inhibits YAP/TAZ-TEAD target genes expression (Cyr61, CTGF, AXL and Survivin) and breast cancer cell proliferation .

HY-RS17160

Ccn2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ccn2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccn2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ccn2 Mouse Pre-designed siRNA Set A Ccn2 Mouse Pre-designed siRNA Set A

HY-168085

CV-4-26	YAP Apoptosis	Cancer
CV-4-26 (Compound 22) is a covalent inhibitor of TEAD. CV-4-26 inhibits YAP/TEAD-based transcription, leading to the reduction of CTGF and CYR61 expression. CV-4-26 inhibits Huh7 and HepG2 cell colony formation, induces cell cycle arrest, and apoptosis. CV-4-26 shows antitumor activity against hepatocellular carcinoma (HCC) and hepatoblastoma (HB) .

HY-P1727A

Super-TDU TFA	YAP	Cancer
Super-TDU TFA is a specific YAP antagonist targeting YAP-TEADs interaction. Super-TDU TFA suppresses tumor growth in gastric cancer mouse model .

HY-P1727

Super-TDU 5 Publications Verification	YAP	Cancer
Super-TDU is a specific YAP antagonist targeting YAP-TEADs interaction. Super-TDU suppresses tumor growth in gastric cancer mouse model .

HY-RS02111

CCN2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CCN2 Human Pre-designed siRNA Set A contains three designed siRNAs for CCN2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CCN2 Human Pre-designed siRNA Set A CCN2 Human Pre-designed siRNA Set A

HY-159912

pan-TEAD-IN-1	YAP	Cancer
pan-TEAD-IN-1 (Compound 3) is an orally active pan-TEAD inhibitor targeting the palmitoylation site of TEAD, disrupting its interaction with the coactivators YAP/TAZ, thereby suppressing the transcriptional upregulation of oncogenes (e.g., *Ctgf* and Cyr61) in the Hippo signaling pathway. pan-TEAD-IN-1 exhibits excellent activity with a luciferase IC₅₀ of 0.36 nM and an H226 cell IC₅₀ of 1.52 nM. It also shows favorable pharmacokinetics (AUC_0–∞ = 228.7 μg/mL·min, T_1/2 = 183.9 min). In TEAD-dependent xenograft mouse models, pan-TEAD-IN-1 significantly inhibited tumor growth, showing promise for research in TEAD-dependent cancers .

HY-10456

TAK-715 Maximum Cited Publications 13 Publications Verification	p38 MAPK Casein Kinase Wnt	Inflammation/Immunology
TAK-715 is an orally active and potent p38 MAPK inhibitor with IC₅₀s of 7.1 nM, 200 nM for p38α and p38β, respectively. TAK-715 inhibits casein kinase I (CK1δ/ε) to regulate activation of Wnt/β-catenin signaling. TAK-715 shows good significant efficacy in a rat arthritis model .

Cat. No.	Product Name	Target	Research Area

HY-P1727

Super-TDU 5 Publications Verification	YAP	Cancer
Super-TDU is a specific YAP antagonist targeting YAP-TEADs interaction. Super-TDU suppresses tumor growth in gastric cancer mouse model .

HY-P1727A

Super-TDU TFA	YAP	Cancer
Super-TDU TFA is a specific YAP antagonist targeting YAP-TEADs interaction. Super-TDU TFA suppresses tumor growth in gastric cancer mouse model .

Cat. No.	Product Name	Target	Research Area

HY-P99288

FG-3019 Pamrevlumab; Anti-Human CTGF Recombinant Antibody	Apoptosis	Cancer
FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF) .

Recombinant Proteins Recommended:

CTGF

Species:	Human (6) Rhesus Macaque (1) Mouse (2) Rat (1)
Tag:	His (5) Tag Free (3) Avi (1) GST (1) Fc (1)
Source:	HEK293 (7) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P70602

	*CCN2/CTGF* Protein, Human (HEK293, Fc)** Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; CTGF; IGFBP8	Human	HEK293
	CCN2/CTGF (Connective Tissue Growth Factor) is a protein produced primarily by endothelial cells in blood vessels. It plays an important role in various cellular processes. CCN2/CTGF Protein, Human (HEK293, Fc) is the recombinant human-derived CCN2/CTGF protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72154

	*CCN2/CTGF* Protein, Mouse (GST)** 1 Publications Verification CCN 2; CCN family member 2; CCN2; Connective tissue growth factor; CTGF; CTGF_HUMAN; Hcs 24; Hcs24; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; IGFBP8; MGC102839; NOV 2; NOV2	Mouse	E. coli
	CCN2/CTGF protein is a major connective tissue mitochondrial attractant secreted by vascular endothelial cells and promotes chondrocyte proliferation and differentiation. It mediates heparin- and divalent cation-dependent cell adhesion in various cell types, including fibroblasts, myofibroblasts, endothelial cells, and epithelial cells. CCN2/CTGF Protein, Mouse (GST) is the recombinant mouse-derived CCN2/CTGF protein, expressed by E. coli , with N-GST labeled tag.

HY-P700701

	*CCN2/CTGF* Protein, Human (HEK293, His)** IGFBP8; IBP-8; CCN2; NOV2; HCS24; CTGF; CTGRP; Fisp12; MGC102839	Human	HEK293
	CCN2/CTGF (Connective Tissue Growth Factor) is a protein produced primarily by endothelial cells in blood vessels. It plays an important role in various cellular processes. CCN2/CTGF Protein, Human (HEK293, His) is the recombinant human-derived CCN2/CTGF protein, expressed by HEK293 , with C-His labeled tag.

HY-P78104

	*CCN2/CTGF* Protein, Human (Biotinylated, HEK293, His-Avi)** 1 Publications Verification IGFBP8; IBP-8; CCN2; NOV2; HCS24; CTGF; CTGRP; Fisp12; MGC102839	Human	HEK293
	CCN2/CTGF (Connective Tissue Growth Factor) is a protein produced primarily by endothelial cells in blood vessels. It plays an important role in various cellular processes. CCN2/CTGF Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CCN2/CTGF protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P72153

	*CCN2/CTGF* Protein, Human (His)** 1 Publications Verification CCN 2; CCN family member 2; CCN2; Connective tissue growth factor; IGFBP-8; IGFBP8; NOV2	Human	E. coli
	CCN2/CTGF Protein, secreted by vascular endothelial cells, crucially promotes chondrocyte proliferation and differentiation, and mediates heparin- and divalent cation-dependent cell adhesion in diverse cell types. Additionally, it enhances fibroblast growth factor-induced DNA synthesis while existing as a monomer and interacting with TSKU. CCN2/CTGF Protein, Human (His) is the recombinant human-derived CCN2/CTGF protein, expressed by E. coli , with N-6*His labeled tag.

HY-P79369

	*CCN2/CTGF* Protein, Rat (HEK293)** CCN family member 2; Ccn2; Cellular communication network factor 2; Connective tissue growth factor; Connective tissue growth-related protein; CTGF	Rat	HEK293
	The CCN2/CTGF protein is a major connective tissue mitochondrial attractant secreted by vascular endothelial cells and critical for chondrocyte proliferation and differentiation. Additionally, it mediates heparin- and divalent cation-dependent cell adhesion in various cell types, including fibroblasts, myofibroblasts, endothelial cells, and epithelial cells. CCN2/CTGF Protein, Rat (HEK293) is the recombinant rat-derived CCN2/CTGF protein, expressed by HEK293 , with tag free.

HY-P70106

	*CCN2/CTGF* Protein, Human (HEK293)** 1 Publications Verification rHuConnective tissue growth factor/CTGF; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8	Human	HEK293
	CCN2/CTGF (Connective Tissue Growth Factor) is a protein produced primarily by endothelial cells in blood vessels. It plays an important role in various cellular processes. CCN2/CTGF Protein, Human (HEK293) is the recombinant human-derived CCN2/CTGF protein, expressed by HEK293 , with tag free.

HY-P78713

	*CCN2/CTGF* Protein, Rhesus macaque (HEK293, His)** CCN2; NOV2; HCS24; IGFBP8; IBP-8; IGFBP-8; IGF-binding protein 8	Rhesus Macaque	HEK293
	CCN2 is a mitogen secreted by vascular endothelial cells and a mechanosensor of mesenchymal cell differentiation that secretes stromal cell proteins. CCN2 can sense appropriate mechanical stress and downregulate its expression accordingly. CCN2 is a classic epithelial-to-mesenchymal transition (EMT) and fibrosis marker. CCN2/CTGF Protein, Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque-derived CCN2/CTGF protein, expressed by HEK293 , with C-His labeled tag.

HY-P704430

	*CCN2/CTGF* Protein, Human** IGFBP8; IBP-8; CCN2; NOV2; HCS24; CTGF; CTGRP; Fisp12; MGC102839	Human	E. coli
	CCN2/CTGF (Connective Tissue Growth Factor) is a protein produced primarily by endothelial cells in blood vessels. It plays an important role in various cellular processes. CCN2/CTGF Protein, Human is the recombinant human-derived CCN2/CTGF protein, expressed by E. coli, with tag free.

HY-P704310

	*CCN2/CTGF* Protein, Mouse (HEK293, His)** CCN 2; CCN family member 2; CCN2; Connective tissue growth factor; CTGF; CTGF_HUMAN; Hcs 24; Hcs24; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; IGFBP8; MGC102839; NOV 2; NOV2	Mouse	HEK293
	CCN2/CTGF protein is a major connective tissue mitochondrial attractant secreted by vascular endothelial cells and promotes chondrocyte proliferation and differentiation. It mediates heparin- and divalent cation-dependent cell adhesion in various cell types, including fibroblasts, myofibroblasts, endothelial cells, and epithelial cells. CCN2/CTGF Protein, Mouse (HEK293, His) is the recombinant mouse-derived CCN2/CTGF protein, expressed by HEK293, with C-His labeled tag.

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81103

	CTGF Antibody CCN 2; CCN-2; CCN2; Connective Tissue Growth Factor; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; connective tissue growth factor precursor; CTGF_HUMAN.	WB, ELISA	Mouse, Rat
	CTGF Antibody is an unconjugated, approximately 36 kDa, rabbit-derived, anti-CTGF polyclonal antibody. CTGF Antibody can be used for: WB, ELISA expriments in mouse, rat, and predicted: human,chicken, dog, pig, cow background without labeling.

HY-P86582

	CTGF Antibody (YA6274) Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8;	WB, IP, ELISA	Human, Mouse, Rat
	CTGF Antibody (YA6274) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CTGF. It can be applicated for WB, IP, ELISA assays, in the background of human, mouse, rat.

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Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS02111

CCN2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CCN2 Human Pre-designed siRNA Set A contains three designed siRNAs for CCN2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS23610

Ccn2 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Ccn2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccn2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17160

Ccn2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ccn2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccn2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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