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Results for "

CPT-2

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

2

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1334A
    Perhexiline maleate
    4 Publications Verification

    		 Mitochondrial Metabolism Apoptosis Cardiovascular Disease Cancer
    Perhexiline maleate is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. Perhexiline maleate induces mitochondrial dysfunction and apoptosis in hepatic cells. Perhexiline maleate can cross the blood brain barrier (BBB) and shows anti-tumor activity. Perhexiline maleate can be used in the research of cancers, and cardiovascular disease like angina [2] .
    Perhexiline maleate
  • HY-107543
    8-pCPT-2′-O-Me-cAMP sodium
    1 Publications Verification

    8-CPT-2'-O-Me-cAMP sodium

    		 Ras Cardiovascular Disease
    8-pCPT-2′-O-Me-cAMP (8-CPT-2'-O-Me-cAMP) sodium, an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac). 8-pCPT-2′-O-Me-cAMP sodium activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50 >10 μM). 8-pCPT-2′-O-Me-cAMP sodium stimulates Epac-mediated Ca 2+ release in pancreatic β-cells in vitro. 8-pCPT-2′-O-Me-cAMP sodium is a Rap1 activator. 8-pCPT-2′-O-Me-cAMP sodium enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration [2] .
    8-pCPT-2′-O-Me-cAMP sodium
  • HY-108433
    CPT2

    Carnitine palmitoyltransferase 2

    		 Apoptosis MDM-2/p53 Metabolic Disease Cancer
    CPT2 (Carnitine palmitoyltransferase 2), an enzyme that participates in fatty acid oxidation, also is a colorectal cancer (CRC) prognostic biomarker. CPT2 overexpression can activate p-p53 to increase p53 expression, thereby inhibiting tumor proliferation and promoting apoptosis. CPT2 deficiency results in the most common inherited disorder of long-chain fatty acid oxidation affecting skeletal muscle. Downregulation of CPT2 is also highly correlated with the progression of various cancers and has potential for cancer research [2].
    CPT2
  • HY-RS03125
    CPT2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CPT2 Human Pre-designed siRNA Set A contains three designed siRNAs for CPT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CPT2 Human Pre-designed siRNA Set A
    CPT2 Human Pre-designed siRNA Set A
  • HY-RS23907
    Cpt2 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    Cpt2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cpt2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Cpt2 Rat Pre-designed siRNA Set A
    Cpt2 Rat Pre-designed siRNA Set A
  • HY-RS17451
    Cpt2 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Cpt2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cpt2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Cpt2 Mouse Pre-designed siRNA Set A
    Cpt2 Mouse Pre-designed siRNA Set A
  • HY-B1334
    Perhexiline

    		Mitochondrial Metabolism Apoptosis Cardiovascular Disease Cancer
    Perhexiline is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. Perhexiline induces mitochondrial dysfunction and apoptosis in hepatic cells. Perhexiline can cross the blood brain barrier (BBB) and shows anti-tumor activity. Perhexiline can be used in the research of cancers, and cardiovascular disease like angina [2] .
    Perhexiline
  • HY-116312
    8-pCPT-2′-O-Me-cAMP

    8-CPT-2'-O-Me-cAMP

    		 Ras Cardiovascular Disease
    8-pCPT-2′-O-Me-cAMP (8-CPT-2'-O-Me-cAMP), an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac). 8-pCPT-2′-O-Me-cAMP activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50 >10 μM). 8-pCPT-2′-O-Me-cAMP stimulates Epac-mediated Ca 2+ release in pancreatic β-cells in vitro. 8-pCPT-2′-O-Me-cAMP is a Rap1 activator. 8-pCPT-2′-O-Me-cAMP enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration [2] .
    8-pCPT-2′-O-Me-cAMP

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