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Isoforms Recommended:	CDK1

Results for "

CCNE1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) CDK (4) Small Interfering RNA (siRNA) (3) Wee1 (2)
By Research Areas:	Cancer (6)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-162255

CDK2-IN-23	CDK	Cancer
CDK2-IN-23 (Compound 17) is a kinase selective and highly potent CDK2 inhibitor (IC₅₀ = 0.29 nM). CDK2-IN-23 shows the pharmacodynamic inhibition of CDK2 in CCNE1-amplified mouse models. CDK2-IN-23 can be used for the research of cancer ^[1].

HY-160701

Cirtociclib BLU-222	CDK Apoptosis	Cancer
Cirtociclib (BLU-222) is an orally active and highly selective CDK2 inhibitor. Cirtociclib disrupts Rb signaling and causes G1 arrest and apoptosis in CCNE1-amplified endometrial cancer cells ^[1] .

HY-145817A

lunresertib 5 Publications Verification RP-6306	Wee1	Cancer
lunresertib (RP-6306) is a potent, selective and orally active *PKMYT1* inhibitor with an IC₅₀ of 14 nM. lunresertib shows a high degree of selectivity over other kinases in cellular binding assays. lunresertib shows anticancer effects ^[1].

HY-RS02127

CCNE1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CCNE1 Human Pre-designed siRNA Set A contains three designed siRNAs for CCNE1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CCNE1 Human Pre-designed siRNA Set A CCNE1 Human Pre-designed siRNA Set A

HY-RS23727

Ccne1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ccne1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccne1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ccne1 Rat Pre-designed siRNA Set A Ccne1 Rat Pre-designed siRNA Set A

HY-RS17273

Ccne1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ccne1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccne1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ccne1 Mouse Pre-designed siRNA Set A Ccne1 Mouse Pre-designed siRNA Set A

HY-175819

PD-166285	Wee1 Apoptosis	Cancer
PD-166285 is a *PKMYT1* inhibitor, with an IC₅₀ value of 17 nM. PD166285 shows strong antiproliferative effects against CCNE1-amplified OVCAR3 cells (IC₅₀ = 0.14 μM) and HCC1569 cells (IC₅₀ = 0.21 μM). PD166285 induces apoptosis and arrests CCNE1-amplified HCC1569 cells at the G1/S phase of the cell cycle. PD166285 can be used for the research of PKMYT1-targeted therapies for CCNE1-amplified cancers ^[1].

HY-175842

CDK2 degrader 7	CDK	Cancer
CDK2 degrader 7 is an orally active CDK2 degrader, with DC₅₀ values of 13 nM (MKN1cells) and 17 nM (TOV21G cells). CDK2 degrader 7 induces G1 phase arrest in MKN1 cells. CDK2 degrader 7 achieves tumor stasis in HCC1569 (CCNE1-amplified) xenograft models. CDK2 degrader 7 can be used for the study of CCNE1-amplified cancers ^[1].

HY-161463

CDK2-IN-28	CDK	Cancer
CDK2-IN-28 (compound 22) is a CDK2 inhibitor with good selectivity and cellular effects against other CDKs. CDK2-IN-28 has anti-proliferative effects on MKN1 cells (EC50: 0.31 μM) ^[1].

Species:	Human (9) Mouse (1)
Tag:	His (9) Tag Free (2) GST (9) Flag (6)
Source:	Sf9 insect cells (11)

Cat. No.	Compare	Product Name	Species	Source

HY-P74214

	Cyclin E Protein, Human (sf9) CCNE; CCNE1; Cyclin E1; G1/S-specific cyclin-E1	Human	Sf9 insect cells
	Cyclin E controls the G1/S transition of the cell cycle. Cyclin E Protein, Human (sf9) is the recombinant human-derived Cyclin E, expressed by Sf9 insect cells , with tag Free labeled tag.

HY-P74257

	*CDK1-CCNE1* Heterodimer Protein, Human (sf9, His-GST)** Cyclin-dependent kinase 1; CDK1; CDC2; G1/S-specific cyclin-E1; CCNE1	Human	Sf9 insect cells
	The FGF-9 protein undergoes autoproteolysis and cholesterol attachment in the endoplasmic reticulum. It acts as a morphogen during development, inducing ventral cell fate, participating in limb bud patterning, and aiding in axon guidance. FGF-9 binds to the PTCH1 receptor and activates target gene transcription when in association with SMO, while PTCH1 represses SMO signaling in the absence of FGF-9. CDK1-CCNE1 Heterodimer Protein, Human (sf9, His-GST) is a recombinant protein dimer complex containing human-derived CDK1-CCNE1 Heterodimer protein, expressed by Sf9 insect cells , with N-10*His, N-GST labeled tag. CDK1-CCNE1 Heterodimer Protein, Human (sf9, His-GST), has molecular weight of ~109.7 (60.4+49.3) kDa.

HY-P72963

	Cyclin E Protein, Human (sf9, His-GST) CCNE; CCNE1; CCNEcyclin Es; Cyclin E1; G1/S-specific cyclin-E1	Human	Sf9 insect cells
	Cyclin E controls the G1/S transition of the cell cycle. Cyclin E Protein, Human (SF9, His-GST) is the recombinant human-derived Cyclin E protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P72964

	Cyclin E Protein, Mouse (sf9, His-GST) CCNE; CCNE1; CCNEcyclin Es; Cyclin E1; G1/S-specific cyclin-E1	Mouse	Sf9 insect cells
	Cyclin E, a vital regulator in cell cycle control, governs the G1/S transition by forming a potent serine/threonine kinase complex with CDK2. This complex, featuring UHRF2, CDK2, and CCNE1, involves Cyclin E's direct interaction with UHRF2, leading to CCNE1 ubiquitination independently of phosphorylation. Cyclin E's intricate dance with CDK2, CABLES1, and CCNA1 highlights its crucial role in tightly regulated cell cycle progression. Cyclin E Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived Cyclin E protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P701364

	*CDK3-CCNE1* Heterodimer Protein, Human (sf9)** CDK3; CCNE1; Cyclin-dependent kinase 3; Cell division protein kinase 3; G1/S-specific cyclin-E1	Human	Sf9 insect cells
	CDK3 protein is a serine/threonine protein kinase that plays a key role in regulating the eukaryotic cell cycle, especially affecting the G0-G1 and G1-S transitions. It interacts with CCNC/cyclin-C during interphase and phosphorylates substrates such as histone H1, ATF1, RB1, and CABLES1. CDK3-CCNE1 Heterodimer Protein, Human (sf9) is a recombinant protein dimer complex containing human-derived CDK3-CCNE1 Heterodimer protein, expressed by sf9 insect cells , with tag free.

HY-P701365

	*CDK3-CCNE1* Heterodimer Protein, Human (sf9, GST, FLAG, His)** CDK3; CCNE1; Cyclin-dependent kinase 3; Cell division protein kinase 3; G1/S-specific cyclin-E1	Human	Sf9 insect cells
	CDK3 protein is a serine/threonine protein kinase that plays a key role in regulating the eukaryotic cell cycle, especially affecting the G0-G1 and G1-S transitions. It interacts with CCNC/cyclin-C during interphase and phosphorylates substrates such as histone H1, ATF1, RB1, and CABLES1. CDK3-CCNE1 Heterodimer Protein, Human (sf9, GST, FLAG, His) is a recombinant protein dimer complex containing human-derived CDK3-CCNE1 Heterodimer protein, expressed by sf9 insect cells , with N-6*His, N-Flag, N-GST labeled tag.

HY-P702680

	CDK3-CCNC Protein, Human (sf9, GST, Flag, His) CDK3; CCNE1; Cyclin-dependent kinase 3; Cell division protein kinase 3; G1/S-specific cyclin-E1	Human	Sf9 insect cells
	CDK3 protein is a serine/threonine protein kinase that plays a key role in regulating the eukaryotic cell cycle, especially affecting the G0-G1 and G1-S transitions. It interacts with CCNC/cyclin-C during interphase and phosphorylates substrates such as histone H1, ATF1, RB1, and CABLES1. CDK3-CCNC Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK3-CCNC, expressed by Sf9 insect cells, with N-Flag, N-His, N-GST labeled tag.

HY-P702681

	*CDK3-CCNE2 Protein, Human (sf9, GST, Flag, His)* CDK3; CCNE1; Cyclin-dependent kinase 3; Cell division protein kinase 3; G1/S-specific cyclin-E1	Human	Sf9 insect cells
	CDK3 protein is a serine/threonine protein kinase that plays a key role in regulating the eukaryotic cell cycle, especially affecting the G0-G1 and G1-S transitions. It interacts with CCNC/cyclin-C during interphase and phosphorylates substrates such as histone H1, ATF1, RB1, and CABLES1. CDK3-CCNE2 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK3-CCNE2, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.

HY-P703475

	*CDK2-CCNE1* Protein, Sus scrofa (sf9, GST, His, Flag)** Cyclin-dependent kinase 2; Cell division protein kinase 2; CDK2; Sus scrofa; Pig; Kinase; Serine/threonine-protein kinase; Transferase; 2.7.11.22	Others	Sf9 insect cells

HY-P702677

	*CDK2-CCNE1* Protein, Human (sf9, GST, His, Flag)** CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2-CCNE1 Protein, Human (sf9, GST, His, Flag) is the recombinant human-derived CDK2-CCNE1, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.

HY-P702673

	*CDK1-CCNE1* Protein, Human (sf9, GST, His, Flag)** CDK1; cyclin-dependent kinase 1; CDC2, cell division cycle 2, G1 to S and G2 to M; CDC28A; p34 protein kinase; cell cycle controller CDC2; cell division protein kinase 1; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; CDC2; P34CDC2; MGC111195; DKFZp686L20222	Human	Sf9 insect cells
	The CDK1/CDC2-cyclin-B complex is a key regulator in the cell cycle. It plays an important role in cell division and development and regulates a variety of cellular activities, including chromosome segregation, nuclear membrane rupture, cytokinesis, etc. The activity of CDK1 is regulated by a variety of phosphorylation and dephosphorylation, thereby controlling the progression of the cell cycle and the DNA repair process. CDK1-CCNE1 Protein, Human (sf9, GST, His, Flag) is the recombinant human-derived CDK1-CCNE1, expressed by Sf9 insect cells, with N-GST, N-Flag, N-His labeled tag.

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HY-P80635

	Cyclin E1 Antibody 1 Publications Verification CCNE1; CCNE; G1/S-specific cyclin-E1	WB, IHC-F, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	Cyclin E1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Cyclin E1.

HY-P80807

	Phospho-Cyclin E1 (Thr395) Antibody CCNE1; CCNE; G1/S-specific cyclin-E1	WB	Human
	Phospho-Cyclin E1 (Thr395) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-Cyclin E1 (Thr395).

HY-P86624

	Cyclin E1 Antibody (YA6316) CCNE1; CCNE; G1/S-specific cyclin-E1	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Cyclin E1 Antibody (YA6316) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cyclin E1.

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CCNE1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CCNE1 Human Pre-designed siRNA Set A contains three designed siRNAs for CCNE1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ccne1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Ccne1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccne1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ccne1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ccne1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccne1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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