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Results for "

CBS

" in MedChemExpress (MCE) Product Catalog:

18

Inhibitors & Agonists

1

Peptides

4

Natural
Products

2

Recombinant Proteins

1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131059
    CBS1117

    		Influenza Virus Infection
    CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A virus, A/Puerto Rico/8/34 (H1N1). CBS1117 interferes with the hemagglutinin (HA)-mediated fusion process .
    CBS1117
  • HY-101556
    Namirotene

    CBS-211A

    		 Drug Derivative Cancer
    Namirotene (CBS-211A) is a retinoic acid analog, which is utilized in topical eye administration. Namirotene enhances 1α,25-dihydroxyvitamin D3-induced cytotoxicity in cell U937 and induces the differentation in U937 .
    Namirotene
  • HY-15300
    Skepinone-L
    1 Publications Verification

    CBS3830

    		 p38 MAPK Autophagy Inflammation/Immunology
    Skepinone-L (CBS3830), a chemical probe, is a selective p38 mitogen-activated protein kinase inhibitor.
    Skepinone-L
  • HY-108716
    Felezonexor

    CBS9106; SL-801

    		 CRM1 Apoptosis Cancer
    CBS9106 (SL-801) is a reversible oral CRM1 inhibitor with CRM1 degrading and antitumor activities. CBS9106, inhibits CRM1-dependent nuclear export, causing arrest of the cell cycle and inducing apoptosis in a time- and dose-dependent manner for a broad spectrum of cancer cells .
    Felezonexor
  • HY-105983A
    CBS-1114 hydrochloride

    		Lipoxygenase Inflammation/Immunology
    CBS-1114 hydrochloride is a potent 5-lipoxygenase inhibitor. CBS-1114 hydrochloride has the potential for inflammation and inflammation-related disorders research .
    CBS-1114 hydrochloride
  • HY-111164
    CBS-3595

    		p38 MAPK Phosphodiesterase (PDE) Inflammation/Immunology
    CBS-3595 is a dual inhibitor of p38 MAP kinase and phosphodiesterase 4 with anti-inflammatory and anti-allodynic activities. CBS-3595 reduces the production of the proinflammatory cytokine IL-6 and increases the levels of the anti-inflammatory cytokine IL-10 in rats. CBS-3595 reduces paw oedema formation in the Complete Freund’s adjuvant (CFA) (HY-153808)-induced arthritis rat model. CBS-3595 is promising for research of autoimmune diseases .
    CBS-3595
  • HY-RS02007
    CBS Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CBS Human Pre-designed siRNA Set A contains three designed siRNAs for CBS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CBS Human Pre-designed siRNA Set A
    CBS Human Pre-designed siRNA Set A
  • HY-RS17100
    Cbs Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Cbs Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cbs gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Cbs Mouse Pre-designed siRNA Set A
    Cbs Mouse Pre-designed siRNA Set A
  • HY-RS23544
    Cbs Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Cbs Rat Pre-designed siRNA Set A contains three designed siRNAs for Cbs gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Cbs Rat Pre-designed siRNA Set A
    Cbs Rat Pre-designed siRNA Set A
  • HY-P5343
    p53 CBS

    p53 Consensus binding sequence

    		 MDM-2/p53 Others
    p53 CBS (p53 Consensus binding sequence) is a biological active peptide. (p53 consensus DNA binding site)
    p53 CBS
  • HY-12852
    Diclosulam

    XDE 564

    		 Herbicide Bacterial Infection
    Diclosulam (XDE 564) is a herbicide with a Ki value of ＜32 nM and MIC and MIC50 values of 6.25, 1.40, 12.5 and 3.01 μM against CBS10913 and CBS12373 strains, respectively .
    Diclosulam
  • HY-W010062
    4-Chlorophenylacetic acid

    		Drug Derivative Cytochrome P450 Estrogen Receptor/ERR Metabolic Disease Cancer
    4-Chlorophenylacetic acid is a halogenated phenylacetic acid derivative. 4-Chlorophenylacetic acid is a potent aromatase inhibitor and antagonizes estrogen signaling. 4-Chlorophenylacetic acid can provide carbon and energy for Pseudomonas sp. strain CBS3. 4-Chlorophenylacetic acid is effective against estrogen-induced mammary tumorigenesis .
    4-Chlorophenylacetic acid
  • HY-163523
    PYRIB-SO 2

    		Microtubule/Tubulin Cancer
    PYRIB-SO 2 is a potent antimitotic agent. PYRIB-SO 2 shows antiproliferative activity and induces cell cycle arrest at G2/M phase. PYRIB-SO 2 reduces and disruptes microtubule structures. PYRIB-SO 2 binds to the colchicine-binding site (C-BS) of α, β-tubulin .
    PYRIB-SO 2
  • HY-121841
    Cannabidiorcol

    O-1821; CBD-C1

    		 TRP Channel Inflammation/Immunology Cancer
    Cannabidiorcol (CBDO, CBD-C1, O-1821) is related to cannabidiol, with the pentyl side chain shortened to a methyl group. Cannabidiorcol has low affinity for cannabinoid receptors (CBs) and is an agonist of the transient receptor potential channel (TRP channel), through which it produces antiinflammatory effects, but can also promote tumorigenesis at high concentrations .
    Cannabidiorcol
  • HY-W010062R
    4-Chlorophenylacetic acid (Standard)

    		Reference Standards Cytochrome P450 Estrogen Receptor/ERR Drug Derivative Metabolic Disease Cancer
    4-Chlorophenylacetic acid (Standard) is the analytical standard of 4-Chlorophenylacetic acid. This product is intended for research and analytical applications. 4-Chlorophenylacetic acid is a halogenated phenylacetic acid derivative. 4-Chlorophenylacetic acid is a potent aromatase inhibitor and antagonizes estrogen signaling. 4-Chlorophenylacetic acid can provide carbon and energy for Pseudomonas sp. strain CBS3. 4-Chlorophenylacetic acid is effective against estrogen-induced mammary tumorigenesis .
    4-Chlorophenylacetic acid (Standard)
  • HY-Y0337
    L-Cysteine
    Maximum Cited Publications
    9 Publications Verification

    Cysteine

    		 Endogenous Metabolite ERK Neurological Disease Metabolic Disease Cancer
    L-Cysteine (Cysteine) is an orally active conditionally essential amino acid with hypoglycemic effects, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H2S pathway. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans. L-Cysteine can be used as an anorectic agent .
    L-Cysteine
  • HY-W016715
    L-Cysteine hydrochloride hydrate
    Maximum Cited Publications
    9 Publications Verification

    		 Endogenous Metabolite NF-κB Insulin Receptor Neurological Disease Metabolic Disease
    L-Cysteine hydrochloride hydrate is an orally active and essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate regulates CBS/H2S pathway, inhibits NF-κB activation and insulin and ghrelin secretion. L-Cysteine hydrochloride hydrate reduces blood sugar, vascular inflammation markers and appetite. L-Cysteine hydrochloride hydrate induces kidney damage. L-Cysteine hydrochloride hydrate can be used in the study of neurological diseases and diabetes .
    L-Cysteine hydrochloride hydrate
  • HY-178466
    Tubulin polymerization/P-gp-IN-1

    		Microtubule/Tubulin P-glycoprotein Apoptosis Cancer
    Tubulin polymerization/P-gp-IN-1 is a Tubulin polymerization/P-gp dual inhibitor. Tubulin polymerization/P-gp-IN-1 inhibits tubulin polymerization and induces G2/M arrest and apoptosis. Tubulin polymerization/P-gp-IN-1 reverses MDR by inhibiting P-gp efflux function. Tubulin polymerization/P-gp-IN-1 has dual functions: direct antitumor activity and reversal of P-gp-mediated Cisplatin (HY-17394) resistance. Tubulin polymerization/P-gp-IN-1 stable binds to the tubulin CBS (ΔG = −12.4 kcal/mol) and the P-gp hydrophobic lumen (ΔG = −10.8 kcal/mol). Tubulin polymerization/P-gp-IN-1 can be used for the study of drug-resistant cervical cancer .
    Tubulin polymerization/P-gp-IN-1

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