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Results for "

C145

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Inhibitory Antibodies

1

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P990802
    Anti-Mouse CD3ε Antibody (145-2C11)

    		CD3 Inflammation/Immunology
    Anti-Mouse CD3ε Antibody (145-2C11) is a kind of Armenian hamster IgG1 in vivo mouse antibody, targeting to CD3ε. The recommend isotype control of Anti-Mouse CD3ε Antibody (145-2C11): Armenian hamster IgG, Isotype Control (HY-P990305).
    Anti-Mouse CD3ε Antibody (145-2C11)
  • HY-152101
    LY1

    		SARS-CoV Infection
    LY1 is a potent, selective and covalent inhibitor against both SARS-CoV-2 PL pro and M pro with Kd values of 1.5 μM and 2.3 μM for M pro C145A protein and PL pro C111A protein, respectively. LY1 potent against the viral proteases, with IC50s of 0.12 μM and 0.99 μM against M pro and PL pro. LY1 shows high selectivity over other kinases, human proteases and metalloenzyme .
    LY1
  • HY-13750
    Ebselen
    10+ Cited Publications

    SPI-1005; PZ-51; CCG-39161

    		 Calcium Channel Virus Protease HIV Phosphatase Infection Neurological Disease Inflammation/Immunology Cancer
    Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker . Ebselen potently inhibits M pro (IC50=0.67 μM) and COVID-19 virus (EC50=4.67 μM) .Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity .
    Ebselen

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