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BAY1128688

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-156701
    BAY-1128688

    		Aldose Reductase Endocrinology
    BAY-1128688 is a potent, orally active and selective AKR1C3 inhibitor with IC50 < 2 nM. BAY-1128688 shows high selectivity over related AKR1C enzymes (1C1, 1C2, 1C4) and AKR1D1. BAY-1128688 exhibits no relevant activity at major nuclear hormone receptors. BAY-1128688 reduces endometriotic lesions in the marmoset monkey endometriosis model. BAY-1128688 can be used for endometriosis research .
    BAY-1128688

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