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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
Results for "

B10 cells

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

3

Peptides

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139696
    AKR1B10-IN-1

    		Aldose Reductase Cancer
    AKR1B10-IN-1 is a potent inhibitor of AKR1B10 (Aldo-Keto Reductase 1B10) with an IC50 of 3.5 nM. AKR1B10-IN-1 suppresses proliferation, metastasis, and Cisplatin (CDDP) resistance of lung cancer cells .
    AKR1B10-IN-1
  • HY-172920
    Wnt/β-catenin-IN-6

    		Wnt β-catenin Inflammation/Immunology Cancer
    Wnt/β-catenin-IN-6 (compound B10) is a potent Wnt/β-catenin pathway inhibitor. Wnt/β-catenin-IN-6 inhibits A549 cells activity with an IC50 of 1.28 μM .
    Wnt/β-catenin-IN-6
  • HY-P1089
    Cytochrome c-pigeon (88-104)

    PCC 88-104

    		 Cytochrome P450 Inflammation/Immunology
    Cytochrome c-pigeon (88-104) (PCC 88-104) has full stimulatory activity for pigeon cytochrome c-primed T cells from B10.A mice. The I-E k-restricted T cell response to Cytochrome c pigeon (pcyt c) is specific for the COOH-terminal sequence 88-104 .
    Cytochrome c-pigeon (88-104)
  • HY-172835
    Rapavir

    JH-B10

    		 HBV Infection
    Rapavir (JH-B10) is a selective and potent sodium taurocholate cotransporting polypeptide (NTCP) inhibitor with an IC50 value of 1.8 nM for the uptake of taurocholic acid-d4 (TCA-d4). Rapavir exerts antiviral activity by directly binding to NTCP and blocking the entry of the virus into cells during the HBV infection phase. Rapavir is promising for research of HBV infections .
    Rapavir
  • HY-146408
    ALK-IN-21

    		Anaplastic lymphoma kinase (ALK) Cancer
    ALK-IN-21 (Compound B10), a potent ALK inhibitor for ALKG1202R mutation, exhibits remarkable enzymatic inhibitory potency with IC50 values of 4.59 nM, 2.07 nM and 5.95 nM toward ALK WT, ALK L1196M and ALK G1202R, respectively. ALK-IN-21 efficiently inhibits the proliferation of ALK-positive Karpas299 and H2228 cells both with IC50 values of 0.07 μM. ALK-IN-21 can be used for the research of anaplastic large cell lymphoma .
    ALK-IN-21
  • HY-108665
    AR-C66096 tetrasodium

    FPL 66096 tetrasodium; PSFM-ATP tetrasodium

    		 P2Y Receptor Cardiovascular Disease
    AR-C66096 tetrasodium is a selective platelet P2YT receptor antagonist. AR-C66096 tetrasodium effectively blocks ADP-induced platelet aggregation. AR-C66096 tetrasodium can be used in the research of thromboembolism .
    AR-C66096 tetrasodium
  • HY-W107409
    Meridianin C

    		Others Cancer
    Meridianin C is a marine natural product with anticancer activity. Meridianin C has significant inhibitory effects on four different human tongue cancer cells (YD-8, YD-10B, YD-38 and HSC-3). Meridianin C most strongly reduced the growth of YD-10B cells, the most aggressive and tumorigenic of the cell lines tested. Meridianin C also induced significant accumulation of large vesicles in YD-10B cells, validating its function through macrophagocytosis. Meridianin C reduces cellular levels of Dickkopf-related protein-3 (DKK-3), a known negative regulator of macrophagy. Meridianin C affects macrophagocytosis by downregulating DKK-3, thereby affecting cell proliferation .
    Meridianin C

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