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Results for "

Aspartate aminotransferase

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

4

Natural
Products

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P3016

    EC 2.6.1.1; GOT; AST

    Endogenous Metabolite Others
    Aspartate aminotransferase, Genetically engineered bacteria (EC 2.6.1.1) (AST) is a transaminase enzyme, is often used in biochemical studies. Aspartate aminotransferase catalyzes aspartate and alpha-ketoglutarate converts to oxaloacetate and glutamate. Aspartate aminotransferase can be found in cerebrospinal fluid, exudates, and transudates .
    Aspartate aminotransferase, Genetically engineered bacteria
  • HY-124825

    Others Cancer
    iGOT1-01 is a potent aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1; GOT1) inhibitor. iGOT1-01 has IC50s of 85 μM and 11.3 μM in MDH coupled GOT1 enzymatic assay and GOT1/GLOX/HRP assay, respectively. iGOT1-01 has anti-cancer activity .
    iGOT1-01
  • HY-P3016A

    Endogenous Metabolite Metabolic Disease
    Glutamate oxaloacetate aminotransferase, porcine heart catalyzes the reversible reaction of L-aspartate and α-ketoglutarate into oxaloacetate and L-glutamate .
    Glutamate oxaloacetate aminotransferase, porcine heart
  • HY-N5092

    Reactive Oxygen Species (ROS) Cytochrome P450 Metabolic Disease
    7-Methylcoumarin is a coumarin derivative with potent hepatoprotective and antioxidant properties. 7-Methylcoumarin is a mechanism-based inhibitor for CYP2A6. 7-Methylcoumarin significantly decreases alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB) in rats with CCl4-induced liver damage, whilst restoring total protein (TP) and albumin (TA) levels in serum as well as preventing oxidative stress. 7-Methylcoumarin can decline mitotic activity of A. sativum promeristem .
    7-Methylcoumarin
  • HY-P3016B

    GOT, Human liver; AST, Human liver

    Endogenous Metabolite Metabolic Disease
    Aspartate aminotransferase (GOT), Human liver is an aminotransferase derived from human liver and is commonly used in biochemical research. Aspartate aminotransferase, Human liver catalyzes the conversion of aspartate and alpha-ketoglutarate to oxaloacetate and glutamate .
    Aspartate aminotransferase, Human liver
  • HY-E70327

    Endogenous Metabolite Others
    Aspartate Aminotransferase, Human is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
    Aspartate Aminotransferase, Human
  • HY-131921

    Biochemical Assay Reagents Endocrinology
    DL-Glyceraldehyde 3-phosphate diethyl acetal barium is an Aspartate Aminotransferase isozyme inhibitor .
    DL-Glyceraldehyde 3-phosphate diethyl acetal barium
  • HY-N4033

    7α-Hydroxyroyleanone

    Bacterial Infection
    Horminone is an abietan diterpene quinone that can be isolated from Labiatae family. Horminone increases of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) serum levels in vivo. Horminone inhibits the growth of Trypanosoma cruzi and shows antibacterial activity .
    Horminone
  • HY-P2891A

    PoxB, Aerococcus viridans

    Endogenous Metabolite Others
    Pyruvate oxidase, Aerococcus viridans (PoxB) is a thiamine pyrophosphate-dependent oxidase that catalyzes the oxidative decarboxylation of pyruvate to produce acetyl phosphate, carbon dioxide, and water. Pyruvate oxidase, Aerococcus viridans is an important enzyme in bacterial metabolism and can enhance ATP production. Additionally, Pyruvate oxidase, Aerococcus viridans can be used for the determination of aspartate aminotransferase and alanine aminotransferase activities .
    Pyruvate oxidase, Aerococcus viridans
  • HY-P1887

    HSP Infection
    p5 Ligand for Dnak and DnaJ is a nonapeptide, which corresponds to the main binding site for the 23-residue part of the presequence of mitochondrial aspartate aminotransferase. p5 Ligand for Dnak and DnaJ is a high-affinity ligand for DnaK and DnaJ .
    p5 Ligand for Dnak and DnaJ
  • HY-N15587

    Gostatine

    Aminotransferases (Transaminases) Metabolic Disease
    Gostatin is an inhibitor of aspartate aminotransferase (GOT). Gostatin is found in Streptomyces sumanensis nov. sp. NK-23. Gostatin has a strong inhibitory effect on pig heart GOT, a weak inhibitory effect on wheat germ GOT and GPT, and no significant effect on glutamate dehydrogenase and glutamine synthetase. The inhibitory mechanism of gostatin is similar to substrate competitive inhibition, and aspartate has a protective effect on its inhibitory effect. Gostatin can be used to study the catalytic mechanism of GOT and its role in nitrogen metabolism .
    Gostatin
  • HY-154629
    Sesame Oil
    1 Publications Verification

    Biochemical Assay Reagents NF-κB Aminotransferases (Transaminases) Interleukin Related NO Synthase Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Sesame Oil is a vegetable oil. Sesame Oil can be extracted from the seeds of Sesamum indicum L. Sesame Oil decreases NF-κB, aspartate aminotransferase, alanine aminotransferase, IL-1β, IL-4 and nitric oxide. Sesame Oil has antitumor activity against malignant melanoma. Sesame Oil has protective effects against liver damage caused by various agents such as Cisplatin (HY-17394) and Acetaminophen (HY-66005). Sesame Oil shows antinociceptive and anti-inflammatory activities .
    Sesame Oil
  • HY-176192

    Toll-like Receptor (TLR) TNF Receptor NF-κB p38 MAPK ERK IKK Inflammation/Immunology
    SMU-14a is a TLR3 inhibitor (IC50: 0.18 µM). SMU-14a inhibits IL-6 secretion in mouse peritoneal macrophages and downregulates TNF-α in human peripheral blood monocytes. SMU-14a exerts anti-inflammatory effects by reducing the phosphorylation of p65, ERK, and TBK1 through NF-κB, MAPK, and IRF3 signaling pathways, and decreasing serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. SMU-14a can be used in the study of acute hepatitis .
    SMU-14a
  • HY-N5092R

    Reference Standards Reactive Oxygen Species (ROS) Cytochrome P450 Metabolic Disease
    7-Methylcoumarin (Standard) is the analytical standard of 7-Methylcoumarin. This product is intended for research and analytical applications. 7-Methylcoumarin is a coumarin derivative with potent hepatoprotective and antioxidant properties. 7-Methylcoumarin is a mechanism-based inhibitor for CYP2A6. 7-Methylcoumarin significantly decreases alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB) in rats with CCl4-induced liver damage, whilst restoring total protein (TP) and albumin (TA) levels in serum as well as preventing oxidative stress. 7-Methylcoumarin can decline mitotic activity of A. sativum promeristem .
    7-Methylcoumarin (Standard)

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