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Results for "

Antipyretic effect

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

2

Natural
Products

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-105808
    Furobufen

    		Others Neurological Disease Inflammation/Immunology
    Furobufen, an anti-inflammatory agent, produces antiarthritic, antipyretic effects. Furobufen has an analgesic effect in inflamed tissue .
    Furobufen
  • HY-N1984
    Artemisic acid

    Qing Hao acid; Artemisinic acid; Arteannuic acid

    		 JNK Interleukin Related Infection Metabolic Disease Inflammation/Immunology Cancer
    Artemisinic acid (Qing Hao acid) is a sesquiterpene that can be isolated from Artemisia annua L. Artemisinic acid is also an important precursor for the synthesis of Artemisinin (HY-B0094). Artemisinic acid has various pharmacological activities, such as antimalarial activity, antitumor activity, antipyretic effect, antibacterial activity, allelopathic effect, and anti-adipogenic effect .
    Artemisic acid
  • HY-114806
    Fenclofenac

    Flenac; R 67408

    		 Thyroid Hormone Receptor Inflammation/Immunology
    Fenclofenac is an orally active anti-inflammatory agent with a low ulcerogenic effect. Fenclofenac also exhibits antipyretic and analgesic activities, with an oral LD50 of 2280 mg/kg in rats. Fenclofenac can be utilized in inflammation research .
    Fenclofenac
  • HY-A0273
    Propyphenazone

    4-Isopropylantipyrine; Isopropylphenazone

    		 COX Inflammation/Immunology
    Propyphenazone (4-Isopropylantipyrine) is an orally active nonacidic pyrazole nonsteroidal anti-inflammatory drug (NSAID). Propyphenazone is a weak nonselective COX inhibitor. Propyphenazone has the effect of reducing pain and antipyretic activity with minimal anti-inflammatory activity .
    Propyphenazone
  • HY-B0363
    Nimesulide
    5+ Cited Publications

    R805

    		 COX Inflammation/Immunology Cancer
    Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties.
    Nimesulide
  • HY-13913
    NS-398
    15+ Cited Publications

    		 COX Inflammation/Immunology Cancer
    NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM.
    NS-398
  • HY-105808R
    Furobufen (Standard)

    		Reference Standards Others Neurological Disease Inflammation/Immunology
    Furobufen (Standard) is the analytical standard of Furobufen. This product is intended for research and analytical applications. Furobufen, an anti-inflammatory agent, produces antiarthritic, antipyretic effects. Furobufen has an analgesic effect in inflamed tissue .
    Furobufen (Standard)
  • HY-N1984R
    Artemisic acid (Standard)

    Qing Hao acid (Standard); Artemisinic acid (Standard); Arteannuic acid (Standard)

    		 Reference Standards JNK Interleukin Related Infection Metabolic Disease Inflammation/Immunology Cancer
    Artemisic acid (Standard) (Qing Hao acid (Standard)) is the analytical standard of Artemisic acid (HY-N1984). This product is intended for research and analytical applications. Artemisinic acid (Qing Hao acid) is a sesquiterpene that can be isolated from Artemisia annua L. Artemisinic acid is also an important precursor for the synthesis of Artemisinin (HY-B0094). Artemisinic acid has various pharmacological activities, such as antimalarial activity, antitumor activity, antipyretic effect, antibacterial activity, allelopathic effect, and anti-adipogenic effect .
    Artemisic acid (Standard)
  • HY-114806R
    Fenclofenac (Standard)

    Flenac (Standard); R 67408 (Standard)

    		 Thyroid Hormone Receptor Reference Standards Inflammation/Immunology
    Fenclofenac (Standard) is the analytical standard of Fenclofenac. This product is intended for research and analytical applications. Fenclofenac is an orally active anti-inflammatory agent with a low ulcerogenic effect. Fenclofenac also exhibits antipyretic and analgesic activities, with an oral LD50 of 2280 mg/kg in rats. Fenclofenac can be utilized in inflammation research .
    Fenclofenac (Standard)
  • HY-A0273R
    Propyphenazone (Standard)

    4-Isopropylantipyrine (Standard); Isopropylphenazone (Standard)

    		 Reference Standards COX Inflammation/Immunology
    Propyphenazone (Standard) is the analytical standard of Propyphenazone. This product is intended for research and analytical applications. Propyphenazone (4-Isopropylantipyrine) is an orally active nonacidic pyrazole nonsteroidal anti-inflammatory drug (NSAID). Propyphenazone is a weak nonselective COX inhibitor. Propyphenazone has the effect of reducing pain and antipyretic activity with minimal anti-inflammatory activity .
    Propyphenazone (Standard)
  • HY-B0363R
    Nimesulide (Standard)

    R805 (Standard)

    		 Reference Standards COX Inflammation/Immunology Cancer
    Nimesulide (Standard) is the analytical standard of Nimesulide. This product is intended for research and analytical applications. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties.
    Nimesulide (Standard)
  • HY-B0363S
    Nimesulide-d5

    		Isotope-Labeled Compounds COX Inflammation/Immunology
    Nimesulide-d5 is a deuterium labeled Nimesulide. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties .
    Nimesulide-d5
  • HY-B0363S1
    Nimesulide-13C6

    R805-13C6

    		 Isotope-Labeled Compounds COX Inflammation/Immunology Cancer
    Nimesulide- 13C6 (R805- 13C6) is 13C labeled Nimesulide. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties.
    Nimesulide-13C6
  • HY-13913R
    NS-398 (Standard)

    		COX Inflammation/Immunology Cancer
    NS-398 (Standard) is the analytical standard of NS-398. This product is intended for research and analytical applications. NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM.
    NS-398 (Standard)
  • HY-105142
    M-5011

    		COX Inflammation/Immunology
    M-5011 is a potent and orally active anti-inflammatory agent. M-5011 shows potent antinociceptive effects and inhibits kaolin (HY-W115786)-induced writhing. M-5011 decreases peritoneal 6-keto-PGF1 alpha levels with low ulcerogenic activities. M-5011 shows anti-inflammatory and anti-pyretic effects and analgesic effect .
    M-5011
  • HY-15036B
    Diclofenac deanol

    DDNL

    		 COX Inflammation/Immunology
    Diclofenac deanol (DDNL) is a nonsteroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic activities. Diclofenac deanol has a more potent inhibitory effect on cyclooxygenase (COX)-2 than on COX-1. The solubility of diclofenac deanol is significantly higher than that of other diflunisal salts reported earlier. Diclofenac deanol has a wide range of potential applications in the medical field due to its biological activity and high water solubility .
    Diclofenac deanol
  • HY-14654A
    Aspirin lithium

    Acetylsalicylic acid lithium; ASA lithium

    		 COX Virus Protease NF-κB Autophagy Apoptosis Mitophagy Caspase p38 MAPK Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Aspirin (Acetylsalicylic Acid) lithium is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin lithium induces apoptosis. Aspirin lithium inhibits the activation of NF-κB. Aspirin lithium also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis .
    Aspirin lithium
  • HY-14654C
    Aspirin calcium

    Acetylsalicylic acid calcium; ASA calcium

    		 COX Virus Protease NF-κB Autophagy Apoptosis Mitophagy Caspase p38 MAPK Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Aspirin calcium is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin calcium induces apoptosis. Aspirin calcium inhibits the activation of NF-κB. Aspirin calcium also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis .
    Aspirin calcium
  • HY-14654
    Aspirin
    Maximum Cited Publications
    29 Publications Verification

    Acetylsalicylic acid; ASA

    		 COX Virus Protease NF-κB Autophagy Apoptosis Mitophagy Caspase p38 MAPK Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Aspirin (Acetylsalicylic acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin induces apoptosis. Aspirin inhibits the activation of NF-κB. Aspirin also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis .
    Aspirin

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