Search Result
Results for "
Antimicrobial-IN-1
" in MedChemExpress (MCE) Product Catalog:
2
Biochemical Assay Reagents
7
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N2544
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-
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- HY-170312
-
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Bacterial
|
Infection
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Antimicrobial-IN-1 (compound 17) exhibits strong antibacterial activity against S. aureus and E. coli, with the inhibition zone diameter of 18 , 16 mm/mg, respectively [1].
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- HY-W683885
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- HY-121272
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-
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- HY-N14233
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-
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- HY-N8916
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- HY-122089
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-
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- HY-145265
-
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Bacterial
|
Infection
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Antimicrobial photosensitizer-1 is a promising candidate as the antimicrobial photosensitizer for combating pathogenic microorganism infections. Antimicrobial photosensitizer-1 exhibits an impressive antimicrobial efficacy in S. aureus-infected mice wounds [1].
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-
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- HY-113582
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-
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- HY-111405
-
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Bacterial
|
Infection
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Antimicrobial Compound 1 is an alkylpyridinium compound, with antimicrobial activity.
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-
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- HY-153722A
-
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Bacterial
|
Infection
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Dodicin hydrochloride is an effective disinfectant with broad antimicrobial activity .
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-
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- HY-N4003
-
|
Bacterial
|
Infection
|
Isobonducellin is a flavonoid product and shows antimicrobial activity .
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-
-
- HY-N15193
-
-
-
- HY-125596
-
|
Parasite
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Infection
|
Lachnumon is a fungal metabolite with nematicidal and antimicrobial activities .
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-
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- HY-P5577
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-
-
- HY-153722
-
|
Bacterial
|
Infection
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Dodicin is an effective disinfectant with broad antimicrobial activity .
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-
-
- HY-146078
-
|
Bacterial
|
Infection
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Antimicrobial agent-1 (compound 6C) possesses potent activity against TolC mutant E. coli with an MIC value of 2 μg/mL. Antimicrobial agent-1 and Colistin exhibit synergistic activity against Gram-negative bacteria. Antimicrobial agent-1 has no cytotoxicity on mammalian cell lines, with MICs > 128 μg/mL in Caco-2 and Vero cell lines [1].
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-
-
- HY-N8148
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-
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- HY-B0343
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-
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- HY-N9468
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-
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- HY-125455
-
|
Bacterial
|
Infection
|
Ro 41-1879 is a catechol cephalosporin that has antimicrobial activity .
|
-
-
- HY-137945
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PheneticillIN sodium; α-PhenoxyethylpenicillIN sodium
|
Bacterial
|
Infection
|
Phenethicillin (α-Phenoxyethylpenicillin) sodium is a Penicillin, and has antimicrobial activity .
|
-
-
- HY-131718
-
|
Bacterial
|
Infection
|
(1-Isothiocyanatoethyl)benzene (compound 27) is an antimicrobial agent .
|
-
-
- HY-156980
-
|
Bacterial
|
Infection
|
Podilfen is an active fraction of Delftia strains 2189 with antimicrobial effects .
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-
-
- HY-N1101
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-
-
- HY-167256
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-
-
- HY-N3060
-
|
Bacterial
|
Infection
|
(S)-5,7-Diacetoxyflavanone is a flavanone with antimicrobial activity .
|
-
-
- HY-122790
-
|
Bacterial
|
Infection
|
2-Hydroxydocosanoic acid has antioxidant, cholinesterase inhibitory, and antimicrobial activities .
|
-
-
- HY-124452
-
DesferrioxamINe E; NocardamIN
|
Bacterial
|
Others
|
Nocardamine (Deferrioxamine E)is an iron carrier/Iron chelator with antimicrobial activity .
|
-
-
- HY-A0153A
-
CefapirIN sodium
|
Bacterial
Antibiotic
|
Infection
|
Cephapirin sodium (Cefapirin sodium) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
|
-
-
- HY-A0153
-
-
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- HY-N7747
-
|
Others
|
Infection
|
Sceptrin dihydrochloride is a compound isolated from the sea sponge Agelas sceptrum that is an antimicrobial agent .
|
-
-
- HY-N8411
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(+)-Aromadendrene
|
Bacterial
|
Infection
|
Aromadendrene can be isolated from Eucalyptus globulus. Aromadendrene has antimicrobial activity .
|
-
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- HY-169745
-
-
-
- HY-121272AS
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-
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- HY-105713
-
|
Bacterial
|
Infection
|
Sulochrin is a metabolite produced by Aspergillus terreus var. aureus. I. Sulochrin has antimicrobial activities .
|
-
-
- HY-137564
-
|
Antibiotic
|
Infection
|
Desacetylcephalothin sodium is a metabolite of Cephalothin (HY-B1275A). Desacetylcephalothin sodium exhibits a weak antimicrobial activity .
|
-
-
- HY-N3636
-
-
-
- HY-N7784
-
|
Antibiotic
Bacterial
|
Infection
|
Liriodenine methiodide is an antibiotic that is active against C. albicans and S. cereuisiae with antimicrobial activities .
|
-
-
- HY-119246
-
-
-
- HY-W251598J
-
Sodium hydrogen carbonate (Pharmaceutical primary standard, USP); Soda bicarbonate (Pharmaceutical primary standard, USP)
|
Bacterial
|
Infection
|
Sodium bicarbonate, United States Pharmacopeia (USP) Reference Standard is an inorganic salt. Sodium bicarbonate shows antimicrobial activity .
|
-
-
- HY-117685
-
|
Bacterial
|
Infection
|
Cefovecin sodium is a cephalosporin. Cefovecin sodium interferes with bacterial cell wall synthesis. Cefovecin sodium shows antimicrobial activator .
|
-
-
- HY-N9880
-
-
-
- HY-121272R
-
-
-
- HY-139570
-
-
-
- HY-P2656
-
hBD-4
|
Bacterial
|
Infection
|
β-Defensin-4 human is an inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity .
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-
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- HY-131102
-
|
Bacterial
DNA/RNA Synthesis
|
Infection
|
Mequindox is an antimicrobial agent . Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice .
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- HY-161312
-
|
Bacterial
Fungal
|
Infection
|
Antifungal agent 93 (compound 10) is a potent antifungal agent. Antifungal agent 93 shows antimicrobial activity .
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-
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- HY-W109613
-
|
Bacterial
|
Infection
|
Methyl dehydroabietate is a kind of resin acid that can be isolated from spruce bark. Methyl dehydroabietate has antimicrobial activities .
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-
-
- HY-128452
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- HY-N14410
-
|
Antibiotic
Bacterial
|
Infection
Cancer
|
Clecarmycin C is an antitumor antibiotic. Clecarmycin C shows cytotoxicity and antitumor activity. Clecarmycin C shows antimicrobial activity .
|
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- HY-N14066
-
|
Fungal
|
Infection
|
Ascochitine, a polyketide-derived secondary metabolite, is a selective antifungal agent. Ascochitine exhibits broad-spectrum phytotoxicity and antimicrobial activities .
|
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- HY-N13961
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XK-88-2
|
Antibiotic
Bacterial
|
Infection
|
Seldomycin factor 2 (XK 88-2) is an aminoglycoside antibiotic. Seldomycin factor 2 has a broad spectrum of antimicrobial activity .
|
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- HY-N3947
-
|
Bacterial
|
Infection
|
Glepidotin B is a dihydroflavonol compound isolated from the extracts of American licorice, Glycyrrhiza lepidota (Leguminosae). Glepidotin B is an antimicrobial agent .
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-
- HY-112057
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LY267108
|
Drug Metabolite
|
Others
|
Pseudoerythromycin A enol ether (LY267108) is a degradation product of Erythromycin. Pseudoerythromycin A enol ether has no significant antimicrobial activity .
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- HY-N13964
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XK 88-3
|
Antibiotic
Bacterial
|
Infection
|
Seldomycin factor 3 (XK 88-3) is an aminoglycoside antibiotic. Seldomycin factor 3 has a broad spectrum of antimicrobial activity .
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- HY-121295
-
|
Bacterial
|
Infection
|
Roseoflavin, a natural pigment originally isolated from Streptomyces davawensis, is an antimetabolite analog of Riboflavin and flavin mononucleotide that has antimicrobial properties .
|
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- HY-N13986
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XX-88-5
|
Antibiotic
Bacterial
|
Infection
|
Seldomycin factor 5 (XK 88-5) is an aminoglycoside antibiotic. Seldomycin factor 5 has a broad spectrum of antimicrobial activity .
|
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- HY-N13959
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XK 88-1
|
Antibiotic
Bacterial
|
Infection
|
Seldomycin factor 1 (XK 88-1) is an aminoglycoside antibiotic. Seldomycin factor 1 has a broad spectrum of antimicrobial activity .
|
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- HY-122428
-
|
Bacterial
|
Infection
|
Samandarone is an alkaloid that can be isolated from the skin gland secretions of Salammedra maculosa and Leptodactylus pentadactylus, which exhibits antimicrobial activity .
|
-
- HY-B0343R
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A-56620 (Standard)
|
Reference Standards
Antibiotic
Bacterial
|
Infection
|
Sarafloxacin (Standard) is the analytical standard of Sarafloxacin. This product is intended for research and analytical applications. Sarafloxacin (A-56620) is a fluoroquinolone antimicrobial agent .
|
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- HY-B0467S
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-
- HY-B0343S
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A-56620-d8
|
Isotope-Labeled Compounds
|
Infection
|
Sarafloxacin-d8 is the deuterium labeled Sarafloxacin(HY-B0343).Sarafloxacin (A-56620) is a fluoroquinolone antimicrobial agent .
|
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- HY-76199R
-
|
Bacterial
Reference Standards
|
Metabolic Disease
|
Phenethicillin (sodium) (Standard) is the analytical standard of Phenethicillin (sodium). This product is intended for research and analytical applications. Phenethicillin (α-Phenoxyethylpenicillin) sodium is a Penicillin, and has antimicrobial activity .
|
-
- HY-137945R
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PheneticillIN sodium (Standard); α-PhenoxyethylpenicillIN sodium (Standard)
|
Bacterial
Reference Standards
|
Infection
|
Phenethicillin (sodium) (Standard) is the analytical standard of Phenethicillin (sodium). This product is intended for research and analytical applications. Phenethicillin (α-Phenoxyethylpenicillin) sodium is a Penicillin, and has antimicrobial activity .
|
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- HY-138137
-
|
Bacterial
|
Infection
|
Menaquinone 6 is a active product found in Wolinella succinogenes. Menaquinone 6 is a form of vitamin K2 (HY-109569) that has antimicrobial activity .
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- HY-N10457
-
|
Bacterial
|
Infection
Cancer
|
Norstictic acid is a potent and selective allossteric transcriptional regulator. Norstictic acid shows anticancer activity. Norstictic acid shows antioxidant activity and antimicrobial activity .
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-
- HY-B1137
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IsopropylamINoantipyrINe
|
Bacterial
|
Inflammation/Immunology
|
Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities .
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- HY-P0324A
-
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Bacterial
|
Infection
|
Parasin I (TFA) is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity .
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- HY-169191
-
|
Bacterial
|
Infection
|
Quorum sensing-IN-8 (compound 5e) has anti-biofilm activity. Quorum sensing-IN-8 can be used for the study of antimicrobial resistance .
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- HY-A0153R
-
CefapirIN (Standard)
|
Reference Standards
Antibiotic
Bacterial
|
Infection
|
Cephapirin (Standard) is the analytical standard of Cephapirin. This product is intended for research and analytical applications. Cephapirin (Cefapirin) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
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- HY-A0153AR
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CefapirIN sodium (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
Cephapirin (sodium) (Standard) is the analytical standard of Cephapirin (sodium). This product is intended for research and analytical applications. Cephapirin sodium (Cefapirin sodium) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
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- HY-149294
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-
- HY-70083
-
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- HY-N1203
-
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- HY-169154
-
|
Bacterial
|
Infection
|
ChlaDUB1-IN-1 (Compound 8) is an inhibitor for Chlamydia deubiquitinase 1 (ChlaDUB1). ChlaDUB1-IN-1 can be used in antimicrobial research .
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- HY-123025
-
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Fungal
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Inflammation/Immunology
|
Schizozygine is an alkaloid that can be isolated from Schizozygia caffaeoides. Schizozygia caffaeoides has been used as a traditional medicine for skin disease. The leaf extracts has high antifungal and antimicrobial activity .
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- HY-131102R
-
|
Reference Standards
Bacterial
DNA/RNA Synthesis
|
Infection
|
Mequindox (Standard) is the analytical standard of Mequindox. This product is intended for research and analytical applications. Mequindox is an antimicrobial agent . Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice .
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- HY-163190
-
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Bacterial
|
Infection
|
NDM-1 inhibitor-4 (compound 27) is a NDM-1 inhibitor with Ki of 1.7 μM. NDM-1 inhibitor-4 has antimicrobial effect .
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- HY-144513
-
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Bacterial
|
Infection
|
Stigmastan-3β-ol is a sterol that can be isolated from Tinospora sinensis and Ginkgo biloba L.. Stigmastan-3β-ol has antimicrobial activity .
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- HY-100589
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Sch 21420 sulfate
|
Bacterial
Antibiotic
|
Infection
|
Isepamicin sulfate (Sch 21420 sulfate) is a broad spectrum aminoglycoside antibiotic. Isepamicin sulfate exhibits considerable antimicrobial activity against Gram-negative non-fermenters in a region with high antimicrobial resistance .
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- HY-149762
-
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Bacterial
|
Infection
|
IMBI (compound 32) is an antibacterial agent that inhibits quorum sensing (QS) against drug-resistant pathogens. IMBI inhibits biofilm formation of Salmonella marcescens and restores or increases its susceptibility to antimicrobial drugs .
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- HY-113627A
-
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Antibiotic
Bacterial
Apoptosis
|
Infection
Inflammation/Immunology
Cancer
|
Undecylprodigiosin hydrochloride, a member of the family of prodiginines, is a potent antibiotic. Undecylprodigiosin hydrochloride can selectively induce apoptosis in human breast carcinoma cells independent of p53. Undecylprodigiosin hydrochloride shows immunosuppressive, anticancer properties and antimicrobial activities .
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- HY-113627
-
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Antibiotic
Bacterial
Apoptosis
|
Infection
Inflammation/Immunology
Cancer
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Undecylprodigiosin, a member of the family of prodiginines, is a potent antibiotic. Undecylprodigiosin can selectively induce apoptosis in human breast carcinoma cells independent of p53. Undecylprodigiosin shows immunosuppressive, anticancer properties and antimicrobial activities .
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- HY-135525
-
-
- HY-B1137S
-
|
Isotope-Labeled Compounds
Bacterial
|
Inflammation/Immunology
|
Ramifenazone-d7 is the deuterium labeled Ramifenazone. Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities .
|
-
- HY-135901
-
|
ADC Payload
Bacterial
|
Cancer
|
Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Py-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity .
|
-
- HY-18061
-
(Rac)-STA-21
|
Antibiotic
STAT
Bacterial
|
Infection
Cancer
|
Ochromycinone ((Rac)-STA-21) is a natural antibiotic and a STAT3 inhibitor. Ochromycinone can inhibits STAT3 DNA binding activity, STAT3 dimerization. Ochromycinone has anticancer and antimicrobial activity .
|
-
- HY-N10528
-
-
- HY-N9096
-
|
Bacterial
|
Neurological Disease
|
Gentiside B has neuritogenic activity and induce neurite outgrowth. Gentiside B can be isolated from the root and rhizome of Gentiana rigescens. Gentiana has hepatoprotective, anti-inflammatory, analgesic, antiproliferative and antimicrobial effects .
|
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- HY-B1137R
-
IsopropylamINoantipyrINe (Standard)
|
Reference Standards
Bacterial
|
Inflammation/Immunology
|
Ramifenazone (Standard) is the analytical standard of Ramifenazone. This product is intended for research and analytical applications. Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities .
|
-
- HY-147777
-
|
Bacterial
DNA/RNA Synthesis
|
Infection
|
14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of 14α-Demethylase/DNA Gyrase. 14α-Demethylase/DNA Gyrase-IN-2 has antimicrobial activities .
|
-
- HY-W004154R
-
|
Biochemical Assay Reagents
Reference Standards
|
Others
|
Ramifenazone (Standard) is the analytical standard of Ramifenazone. This product is intended for research and analytical applications. Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities .
|
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- HY-B1290
-
Phenylethyl alcohol; Phenethyl alcohol; Benzyl carbINol
|
Bacterial
Virus Protease
|
Infection
|
2-Phenylethanol (Phenethyl alcohol) is an aromatic alcohol with a rose-like odour. 2-Phenylethanol is a flavour and fragrance compound, and can be used as a preservative and anti-microbial agent. 2-Phenylethanol has antityrosinase and antimicrobial activities .
|
-
- HY-145417
-
|
Bacterial
|
Infection
|
G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter. Transmembrane ATP-binding cassette (ABC) transporters are crucial cellular machines that move molecules small and large across membranes. G092 has the potential for the research of antimicrobial agents .
|
-
- HY-147778
-
|
Bacterial
DNA/RNA Synthesis
|
Infection
|
14α-Demethylase/DNA Gyrase-IN-1 (Compound 7c) is a potent inhibitor of 14α-Demethylase/DNA Gyrase. 14α-Demethylase/DNA Gyrase-IN-1 has antimicrobial activities .
|
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- HY-N5190
-
|
Antibiotic
Bacterial
|
Infection
|
Enamidonin is a lipopeptide antibiotic. Enamidonin inhibits EGF-dependent [ 3H] thymidine involvement in Balb/MK cells (IC50 is 10 μg/mL), and it can restore the deformed SRCTS-NRK form to the normal flat form (ED50 is 10 μg/mL). No antimicrobial activity .
|
-
- HY-W743292
-
PheneticillIN sodium-d5; α-PhenoxyethylpenicillIN sodium-d5
|
Isotope-Labeled Compounds
Bacterial
|
Infection
|
Phenethicillin sodium-d5 (Pheneticillin sodium-d5; α-Phenoxyethylpenicillin sodium-d5) is the deuterium labeled Phenethicillin sodium (HY-137945). Phenethicillin (α-Phenoxyethylpenicillin) sodium is a Penicillin, and has antimicrobial activity .
|
-
- HY-176055
-
|
Carbonic Anhydrase
|
Infection
|
hCAI/II-IN-11 (compound 2c) is a Carbonic Anhydrase Inhibitor with IC50 values of 12.56 μM and 13.02 μM for hCA I and hCA II, respectively. hCAI/II-IN-11 shows antioxidant and antimicrobial effects .
|
-
- HY-126462
-
|
Bacterial
|
Infection
|
Lantic acid is a triterpenoid compound possessing antimicrobial activity. Lantic acid exhibits inhibitory effects on a broad range of both Gram-positive and Gram-negative bacteria, with particular potency against Escherichia coli and Bacillus subtilis. Lantic acid is utilized in the research and development of antimicrobial agents .
|
-
- HY-N14245
-
|
Melanocortin Receptor
|
Cancer
|
Melanoxazal is a Melanin biosynthesis inhibitor. Melanoxazal can inhibit melanin formation in the silkworm larva hemolymph (IC50 is 30.1 μg/mL), and also has stronger inhibitory effect against mushroom tyrosinase (IC50 is 4.2 μg/mL), but it has no antimicrobial effect .
|
-
- HY-N7906
-
MyricetIN 3-β-D-glucopyranoside
|
Bacterial
Parasite
Antibiotic
|
Infection
Inflammation/Immunology
|
Myricetin 3-O-glucoside (Myricetin 3-β-D-glucopyranoside) is a flavonol from Tibouchina paratropica and Hakmeitau beans. Myricetin 3-O-glucoside exhibits anti-Leishmanial, anti-inflammatory and antimicrobial activities .
|
-
- HY-100435
-
MCB-3837; DNV3837
|
Bacterial
|
Infection
|
Oxaquin (MCB-3837) is a injectable proagent that is rapidly converted to the active substance MCB3681 in vivo following intravenous (i.v.) administration, active against Gram-positive bacterial species. Oxaquin (MCB-3837) itself has no antimicrobial effects .
|
-
- HY-126662
-
|
Antibiotic
Bacterial
|
Infection
|
Netzahualcoyone is a triterpenoid compound isolated from the Celastraceae plant family. Netzahualcoyone exhibits broad-spectrum antibiotic activity against Gram-positive bacteria and yeasts, but is not active against Gram-negative bacteria. Netzahualcoyone can be utilized in the development of antibiotics and for studying antimicrobial mechanisms .
|
-
- HY-151918
-
|
Bacterial
|
Infection
Inflammation/Immunology
|
Antibacterial agent 125 is an antibacterial agent. Antibacterial agent 125 has a potent antimicrobial activity against clinically relevant Gram-positive pathogens with MIC50 values range from 0.25 - 8 μM. Antibacterial agent 125 can be used for the research of antimicrobial resistance .
|
-
- HY-P10564
-
|
Bacterial
|
Infection
|
Pardaxin P 4 is an antimicrobial peptide found in the secretions of Red Sea Moses sole. Pardaxin P 4 acts as a biomembrane perforator that can interact with phospholipid bilayers of different compositions and induce cytotoxicity and pore formation. Pardaxin P 4 can be used in the research of antimicrobial drugs .
|
-
- HY-W075770
-
Nickel monoxide
|
Bacterial
Reactive Oxygen Species (ROS)
|
Infection
Metabolic Disease
Cancer
|
Nickel(II) oxide is a chemical compound which nanoparticle form (NiO NPs) exhibits antibacterial, antifungal, antileishmanial, anti-diabetic and anticancer activities. NiO NPs can be activated by ultraviolet and visible light to generate reactive oxygen species, which may be the main cause for the antimicrobial potential .
|
-
- HY-169973
-
|
Beta-lactamase
Bacterial
|
Infection
|
PhoPS is the photocaged inhibitor for β-lactamase. PhoPS is activated upon light irradiation, and active β-lactamase inhibitor Sulbactam (HY-B0334) is released. PhoPS inhibits the synthesis of bacterial cell wall and the formation of E. coli biofilm, exhibits antimicrobial activity .
|
-
- HY-32865
-
|
Bacterial
Drug Intermediate
|
Infection
|
tert-Butyl 2,2,2-trichloroacetimidate is a tert-butylation reagent. tert-Butyl 2,2,2-trichloroacetimidate achieves mild, nonreversible tert-butylation of alcohols and phenols. tert-Butyl 2,2,2-trichloroacetimidate is used in the synthesis of antimicrobial agents .
|
-
- HY-77813S
-
|
Isotope-Labeled Compounds
Bacterial
Apoptosis
Antibiotic
|
Endocrinology
Cancer
|
Benzyl isothiocyanate-d7 is the deuterium labeled Benzyl isothiocyanate. Benzyl isothiocyanate is a member of natural isothiocyanates with antimicrobial activity . Benzyl isothiocyanate potent inhibits cell mobility, migration and invasion nature and matrix metalloproteinase-2 (MMP-2) activity of murine melanoma cells .
|
-
- HY-B1794
-
-
- HY-139745A
-
|
Beta-lactamase
Bacterial
|
Infection
|
FPI-1523, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 exhibits considerable antimicrobial activity .
|
-
- HY-P10536
-
|
Bacterial
|
Infection
|
Temporin SHF is a broad-spectrum antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria and yeasts, but does not have hemolytic activity. Temporin SHF disrupts the acyl chain stacking of anionic lipid bilayers, leading to cracks and disintegration of microbial membranes. Temporin SHF can be used in the development of antimicrobial drugs .
|
-
- HY-19992
-
Bromopyruvic acid; HexokINase II INhibitor II, 3-BP
|
Hexokinase
Apoptosis
Autophagy
|
Cancer
|
3-Bromopyruvate (Bromopyruvic acid) is an analogue of pyruvate and a potent hexokinase (HK)-II inhibitor with high tumor selectivity. 3-Bromopyruvate inhibits cell growth and induces apoptosis through interfering with glycolysis. 3-Bromopyruvate induces autophagy by stimulating ROS formation in breast cancer cells. Antimicrobial activities .
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- HY-139324
-
|
GSK-3
Amyloid-β
|
Neurological Disease
Cancer
|
Cu(II)GTSM, a cell-permeable Cu-complex, significantly inhibits GSK3β. Cu(II)GTSM inhibits Amyloid-β oligomers (AβOs) and decreases tau phosphorylation. Cu(II)GTSM also decreases the abundance of Amyloid-β trimers. Cu(II)GTSM is a potential anticancer and antimicrobial agent .
|
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- HY-E70030
-
|
Bacterial
|
Infection
|
GlcNAc 1-P uridyltransferase (CjGlmU) is a sugar nucleotidyltransferase (SNT). GlcNAc 1-P uridyltransferase (CjGlmU) utilizes UTP and GlcNAc-1-P as its natural substrates, synthesizes UDP-GlcNAc. GlcNAc 1-P uridyltransferase (CjGlmU) has the potential for the research of antimicrobial agents .
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- HY-162624
-
|
Bacterial
|
Infection
|
Quorum sensing-IN-5 is a RpfF-targeted quorum-sensing inhibitor. Quorum sensing-IN-5 inhibits Xanthomonas oryzae pv oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac) with EC50 values of 9.91 μg/mL and 7.04 μg/mL. Quorum sensing-IN-5 has antimicrobial activity .
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- HY-139745
-
|
Beta-lactamase
Bacterial
|
Infection
|
FPI-1523 sodium, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 sodium also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 sodium exhibits considerable antimicrobial activity .
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- HY-P10539
-
|
Bacterial
|
Infection
|
Hp1404 is a novel cationic antimicrobial peptide. Hp1404 has specific inhibitory activity against Gram-positive bacteria, including Staphylococcus aureus (MRSA) resistant to Laburnetin (HY-N7382). Hp1404 has antimicrobial activity, low toxicity, and is not prone to drug resistance, and can be used in the research of antimicrobial agents .
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- HY-W040795
-
|
DNA/RNA Synthesis
Endogenous Metabolite
|
Infection
|
N2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent .
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- HY-135900
-
|
ADC Payload
Bacterial
|
Cancer
|
Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Aniline-MPB-amino-C3-PBD is a sequence-selective DNA minor-groove binding agent. Aniline-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity .
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- HY-P10411
-
|
Bacterial
|
Infection
|
BING is an antimicrobial peptide that can be isolated from Japanese medaka fish. BING shows a broad-spectrum toxicity against pathogenic bacteria including drug-resistant strains. BING induces a deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, and reduces the RNA level of cpxR, which plays a crucial role in the development of antimicrobial resistance .
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- HY-B1794A
-
|
Dopamine Receptor
Histamine Receptor
Bacterial
Amyloid-β
|
Infection
Neurological Disease
|
Thiethylperazine dimaleate, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine dimaleate is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine dimaleate has anti-emetic, antipsychotic and antimicrobial effects .
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- HY-B1290R
-
Phenylethyl alcohol (Standard); Phenethyl alcohol (Standard); Benzyl carbINol (Standard)
|
Virus Protease
Bacterial
Reference Standards
|
Infection
|
2-Phenylethanol (Standard) is the analytical standard of 2-Phenylethanol. This product is intended for research and analytical applications. 2-Phenylethanol (Phenethyl alcohol) is an aromatic alcohol with a rose-like odour. 2-Phenylethanol is a flavour and fragrance compound, and can be used as a preservative and anti-microbial agent. 2-Phenylethanol has antityrosinase and antimicrobial activities .
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- HY-167685
-
|
Bacterial
|
Inflammation/Immunology
|
(E/Z)-Aureusidin is a flavonoid compound with antioxidant activity. (E/Z)-Aureusidin can inhibit the production of reactive oxygen species and reduce cell damage. (E/Z)-Aureusidin has anti-inflammatory effects and can reduce the expression of inflammatory factors. (E/Z)-Aureusidin has inhibitory effects on a variety of bacteria, indicating its potential antimicrobial properties .
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- HY-170810
-
|
Bacterial
|
Infection
|
E.coli Gyrase B-IN-1 (Compound 10g) is a E.coli Gyrase B inhibitor with antibacterial activities. E.coli Gyrase B-IN-1 has potent inhibitory activity against E. coli, with a MIC value of 0.12 mM. E.coli Gyrase B-IN-1 is promising for research of antimicrobial agents .
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- HY-N7510
-
12-Methoxycarnosic acid
|
5 alpha Reductase
|
Infection
Cancer
|
12-O-Methylcarnosic acid (12-Methoxycarnosic acid), a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid inhibits proliferation in LNCaP cells. 12-O-Methylcarnosic acid has antioxidant, anti-cancer and antimicrobial activity .
|
-
- HY-B1290S3
-
Phenylethyl alcohol-13C2; Phenethyl alcohol-13C2; Benzyl carbINol-13C2
|
Bacterial
Virus Protease
Isotope-Labeled Compounds
|
Infection
|
2-Phenylethanol- 13C2 is 13C labeled 2-Phenylethanol (HY-B1290). 2-Phenylethanol (Phenethyl alcohol) is an aromatic alcohol with a rose-like odour. 2-Phenylethanol is a flavour and fragrance compound, and can be used as a preservative and anti-microbial agent. 2-Phenylethanol has antityrosinase and antimicrobial activities .
|
-
- HY-P10306
-
|
Bacterial
|
Infection
|
Cys-LL37 is a biomaterial with antimicrobial properties developed by covalently fixing to the surface of titanium. Cys-LL37 uses a flexible hydrophilic polyethylene glycol spacer and selective n-terminal coupling LL37, a surface peptide layer that kills bacteria on contact is formed. Cys-LL37 can be used in research to develop new antimicrobial biomaterials .
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-
- HY-P10556
-
|
Bacterial
|
Infection
|
(KFF)3K is a cell penetrating peptide that can promote the absorption of other antibiotics by disrupting the outer membrane of bacteria. (KFF)3K can be introduced into a hydrocarbon scaffold to induce its antibacterial properties, making it an effective antimicrobial peptide. (KFF)3K can be used in the development of new antimicrobial agents .
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- HY-B1794R
-
|
Dopamine Receptor
Histamine Receptor
Bacterial
Amyloid-β
|
Infection
Neurological Disease
|
Thiethylperazine (Standard) is the analytical standard of Thiethylperazine. This product is intended for research and analytical applications. Thiethylperazine, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine has anti-emetic, antipsychotic and antimicrobial effects .
|
-
- HY-144659
-
|
Beta-lactamase
Apoptosis
Bacterial
|
Infection
|
Metallo-β-lactamase-IN-5 (compound 5c) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-5 shows inhibitory activity against MBLs NDM-1 and VIM-1. Metallo-β-lactamase-IN-5 inhibits HUVECs with an IC50 of 45 μg/mL. Metallo-β-lactamase-IN-5 plus Imipenem exhibits synergistic antimicrobial activity .
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-
- HY-N14323
-
|
Interleukin Related
|
Inflammation/Immunology
|
Madindoline A is an IL-6 inhibitor. Madindoline A inhibits IL-6-dependent MH-60 cells and has no inhibitory effect on IL-6-independent MH-60 cells. In the presence of 0.1 U/mL IL-6, it inhibits IL-6-dependent MH-60 cells with an IC50 of 8 μM. Madindoline A has no antimicrobial effect .
|
-
- HY-P5057B
-
|
Fluorescent Dye
Bacterial
|
Infection
|
5-FAM-Ahx-LL-37 TFA is a 5-FAM (HY-66022) labeled LL-37, human (HY-P1222). The carboxyfluorescein group is attached via a 6-carbon spacer, 6-Aminohexanoic acid (Ahx, HY-B0236). LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity .
|
-
- HY-B1794AR
-
|
Dopamine Receptor
Histamine Receptor
Bacterial
Amyloid-β
|
Infection
Neurological Disease
|
Thiethylperazine (dimaleate) (Standard) is the analytical standard of Thiethylperazine (dimaleate). This product is intended for research and analytical applications. Thiethylperazine dimaleate, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine dimaleate is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine dimaleate has anti-emetic, antipsychotic and antimicrobial effects .
|
-
- HY-W013376
-
1-(Diphenylmethyl)piperazINe; 1-BenzhydrylpiperazINe
|
Antibiotic
Bacterial
Penicillin-binding protein (PBP)
|
Infection
Cancer
|
Norcyclizine is a piperazine compound that can be used for the synthesis of antimicrobial agents. 1-Benzhydrylpiperazine derivatives have been found to enhance the antibacterial activity of β-lactam antibiotics (Oxacillin, HY-B0925A) against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). This enhancement is likely achieved by inhibiting the allosteric site of PBP2a. Additionally, 1-Benzhydrylpiperazine can also serve as a pharmacological scaffold for the synthesis of anticancer agents [1] .
|
-
- HY-N14325
-
|
Interleukin Related
|
Infection
|
Madindoline B is an IL-6 inhibitor. Madindoline B inhibits IL-6-dependent MH-60 cells and has no inhibitory effect on IL-6-independent MH-60 cells. In the presence of 0.1 U/mL IL-6, it inhibits IL-6-dependent MH-60 cells with an IC50 of 30 μM. Madindoline B has no antimicrobial effect .
|
-
- HY-N7510R
-
12-Methoxycarnosic acid (Standard)
|
Reference Standards
5 alpha Reductase
|
Infection
Cancer
|
12-O-Methylcarnosic acid (Standard) is the analytical standard of 12-O-Methylcarnosic acid. This product is intended for research and analytical applications. 12-O-Methylcarnosic acid (12-Methoxycarnosic acid), a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid inhibits proliferation in LNCaP cells. 12-O-Methylcarnosic acid has antioxidant, anti-cancer and antimicrobial activity .
|
-
- HY-170991
-
|
Bacterial
Reactive Oxygen Species (ROS)
|
Infection
|
C12-rrw-NH2 (Compound Lip7) is an antibacterial agent against gram-positive bacteria, especially against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). C12-rrw-NH2 induces bacterial death via depolarizing the bacterial cytoplasmic membrane, disrupting the integrity of the bacterial membrane, leading to leakage of nucleic acid and protein and promoting the generation of Reactive Oxygen Species. C12-rrw-NH2 is potential to be used for research of developing high-stability antimicrobial peptides .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-124452
-
DesferrioxamINe E; NocardamIN
|
Chelators
|
Nocardamine (Deferrioxamine E)is an iron carrier/Iron chelator with antimicrobial activity .
|
-
- HY-W251598J
-
Sodium hydrogen carbonate (Pharmaceutical primary standard, USP); Soda bicarbonate (Pharmaceutical primary standard, USP)
|
Buffer Reagents
|
Sodium bicarbonate, United States Pharmacopeia (USP) Reference Standard is an inorganic salt. Sodium bicarbonate shows antimicrobial activity .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P0324A
-
|
Bacterial
|
Infection
|
Parasin I (TFA) is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity .
|
-
- HY-P5057B
-
|
Fluorescent Dye
Bacterial
|
Infection
|
5-FAM-Ahx-LL-37 TFA is a 5-FAM (HY-66022) labeled LL-37, human (HY-P1222). The carboxyfluorescein group is attached via a 6-carbon spacer, 6-Aminohexanoic acid (Ahx, HY-B0236). LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity .
|
-
- HY-P5577
-
-
- HY-P2656
-
hBD-4
|
Bacterial
|
Infection
|
β-Defensin-4 human is an inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity .
|
-
- HY-P10564
-
|
Bacterial
|
Infection
|
Pardaxin P 4 is an antimicrobial peptide found in the secretions of Red Sea Moses sole. Pardaxin P 4 acts as a biomembrane perforator that can interact with phospholipid bilayers of different compositions and induce cytotoxicity and pore formation. Pardaxin P 4 can be used in the research of antimicrobial drugs .
|
-
- HY-P10536
-
|
Bacterial
|
Infection
|
Temporin SHF is a broad-spectrum antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria and yeasts, but does not have hemolytic activity. Temporin SHF disrupts the acyl chain stacking of anionic lipid bilayers, leading to cracks and disintegration of microbial membranes. Temporin SHF can be used in the development of antimicrobial drugs .
|
-
- HY-P10539
-
|
Bacterial
|
Infection
|
Hp1404 is a novel cationic antimicrobial peptide. Hp1404 has specific inhibitory activity against Gram-positive bacteria, including Staphylococcus aureus (MRSA) resistant to Laburnetin (HY-N7382). Hp1404 has antimicrobial activity, low toxicity, and is not prone to drug resistance, and can be used in the research of antimicrobial agents .
|
-
- HY-P10411
-
|
Bacterial
|
Infection
|
BING is an antimicrobial peptide that can be isolated from Japanese medaka fish. BING shows a broad-spectrum toxicity against pathogenic bacteria including drug-resistant strains. BING induces a deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, and reduces the RNA level of cpxR, which plays a crucial role in the development of antimicrobial resistance .
|
-
- HY-P10306
-
|
Bacterial
|
Infection
|
Cys-LL37 is a biomaterial with antimicrobial properties developed by covalently fixing to the surface of titanium. Cys-LL37 uses a flexible hydrophilic polyethylene glycol spacer and selective n-terminal coupling LL37, a surface peptide layer that kills bacteria on contact is formed. Cys-LL37 can be used in research to develop new antimicrobial biomaterials .
|
-
- HY-P10556
-
|
Bacterial
|
Infection
|
(KFF)3K is a cell penetrating peptide that can promote the absorption of other antibiotics by disrupting the outer membrane of bacteria. (KFF)3K can be introduced into a hydrocarbon scaffold to induce its antibacterial properties, making it an effective antimicrobial peptide. (KFF)3K can be used in the development of new antimicrobial agents .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-N7510
-
-
- HY-N14323
-
-
- HY-N14325
-
-
- HY-N7510R
-
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B0467S
-
|
Amoxicillin-d4 is a deuterium labeled Amoxicillin. Amoxicillin is an antibiotic with good oral absorption and broad spectrum antimicrobial activity .
|
-
-
- HY-121272AS
-
|
Difloxacin-d3 (hydrochloride trihydrate) is a deuterium labeled Difloxacin. Difloxacin is an antimicrobial agent .
|
-
-
- HY-B0343S
-
|
Sarafloxacin-d8 is the deuterium labeled Sarafloxacin(HY-B0343).Sarafloxacin (A-56620) is a fluoroquinolone antimicrobial agent .
|
-
-
- HY-B1137S
-
|
Ramifenazone-d7 is the deuterium labeled Ramifenazone. Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities .
|
-
-
- HY-W743292
-
|
Phenethicillin sodium-d5 (Pheneticillin sodium-d5; α-Phenoxyethylpenicillin sodium-d5) is the deuterium labeled Phenethicillin sodium (HY-137945). Phenethicillin (α-Phenoxyethylpenicillin) sodium is a Penicillin, and has antimicrobial activity .
|
-
-
- HY-77813S
-
|
Benzyl isothiocyanate-d7 is the deuterium labeled Benzyl isothiocyanate. Benzyl isothiocyanate is a member of natural isothiocyanates with antimicrobial activity . Benzyl isothiocyanate potent inhibits cell mobility, migration and invasion nature and matrix metalloproteinase-2 (MMP-2) activity of murine melanoma cells .
|
-
-
- HY-B1290S3
-
|
2-Phenylethanol- 13C2 is 13C labeled 2-Phenylethanol (HY-B1290). 2-Phenylethanol (Phenethyl alcohol) is an aromatic alcohol with a rose-like odour. 2-Phenylethanol is a flavour and fragrance compound, and can be used as a preservative and anti-microbial agent. 2-Phenylethanol has antityrosinase and antimicrobial activities .
|
-
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