Alkyne Cholesterol

By Targets:	Apoptosis (1) Autophagy (1) Biochemical Assay Reagents (7) Liposome (1) PPAR (1)
By Research Areas:	Cancer (1) Infection (1) Inflammation/Immunology (1) Metabolic Disease (4)
Click Chemistry:	Labeling and Fluorescence Imaging (1) Azide (1) Alkynes (3)
Oligonucleotides:	Cholesterol (1)

Targets Recommended: Acyltransferase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-151705

**Alkyne Cholesterol** 1 Publications Verification	Liposome	Metabolic Disease
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-171562

Cholesterol-SA-PEG-Azide (MW 2000)	Biochemical Assay Reagents	Metabolic Disease
Cholesterol-SA-PEG-Azide (MW 2000) is a lipid that can be used for drug delivery. Cholesterol-SA-PEG-Azide (MW 2000) contains Cholesterol (HY-N0322), Succinic acid (HY-N0420), PEG units and an azide group. Cholesterol-SA-PEG-Azide (MW 2000) contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .

HY-N0364

Falcarindiol 1 Publications Verification	Apoptosis Autophagy PPAR	Infection Metabolic Disease Inflammation/Immunology Cancer
Falcarindiol, an orally active polyacetylenic oxylipin, activates PPARγ and increases the expression of the cholesterol transporter ABCA1 in cells. Falcarindiol induces apoptosis and autophagy. Falcarindiol has anti-inflammatory, antifungal, anticancer and antidiabetic properties . Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-137018

27-Alkyne cholesterol	Biochemical Assay Reagents	Others
27-Alkyne cholesterol is a modified lipid containing an omega-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as click chemistry, in the presence of a copper-containing catalyst. Alkyne cholesterol represents a versatile, sensitive, and easy-to-use tool for tracking cellular cholesterol metabolism and localization as it allows for manifold detection methods including mass spectrometry, and fluorescence microscopy.

HY-174924A

Cholesterol-PEG8-azide	Biochemical Assay Reagents	Others
Cholesterol-PEG8-azide is a PEG derivative composed of Cholesterol, 8 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

HY-174924

Cholesterol-PEG3-azide	Biochemical Assay Reagents	Others
Cholesterol-PEG3-azide is a PEG derivative composed of Cholesterol, 3 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

HY-N15960

Photoclick cholesterol II	Biochemical Assay Reagents	Others
Photoclick cholesterol II is a sterol lipid Cholesterol (HY-N0322) analog that contains a clickable terminal alkyne moiety and a photoactivatable diaziridine group.

HY-W782122

Photoclick cholesterol	Biochemical Assay Reagents	Others
Photoclick cholesterol is a sterol lipid cholesterol analog that contains a clickable terminal alkyne moiety and a photoactivatable diaziridine group. Photoclick cholesterol has the ability to photoaffinity label the mitochondrial outer membrane transport protein (TSPO) and is able to specifically bind cholesterol to TSPO. However, using excessive amounts of Photoclick cholesterol will reduce the photolabeling of total mitochondrial proteins and TSPO .

HY-173385

Cholesteryl-PEG1000-Azide	Biochemical Assay Reagents	Metabolic Disease
Cholesteryl-PEG1000-Azide is a lipid that can be used for drug delivery. Cholesteryl-PEG1000-Azide is attached to the cholesterol backbone with a PEG unit on one side and an azide unit on the other side of the PEG. Cholesteryl-PEG1000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .

Cat. No.	Product Name	Type

HY-151705

**Alkyne Cholesterol** 1 Publications Verification	Drug Delivery
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-171562

Cholesterol-SA-PEG-Azide (MW 2000)	Drug Delivery
Cholesterol-SA-PEG-Azide (MW 2000) is a lipid that can be used for drug delivery. Cholesterol-SA-PEG-Azide (MW 2000) contains Cholesterol (HY-N0322), Succinic acid (HY-N0420), PEG units and an azide group. Cholesterol-SA-PEG-Azide (MW 2000) contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .

HY-174924A

Cholesterol-PEG8-azide	Drug Delivery
Cholesterol-PEG8-azide is a PEG derivative composed of Cholesterol, 8 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

HY-174924

Cholesterol-PEG3-azide	Drug Delivery
Cholesterol-PEG3-azide is a PEG derivative composed of Cholesterol, 3 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

HY-173385

Cholesteryl-PEG1000-Azide	Drug Delivery
Cholesteryl-PEG1000-Azide is a lipid that can be used for drug delivery. Cholesteryl-PEG1000-Azide is attached to the cholesterol backbone with a PEG unit on one side and an azide unit on the other side of the PEG. Cholesteryl-PEG1000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0364

Falcarindiol 1 Publications Verification	Infection Structural Classification Natural Products Chrysanthemum × morifolium (Ramat.) Hemsl. Classification of Application Fields Source classification Metabolic Disease Umbelliferae Plants Inflammation/Immunology Disease Research Fields	Apoptosis Autophagy PPAR
Falcarindiol, an orally active polyacetylenic oxylipin, activates PPARγ and increases the expression of the cholesterol transporter ABCA1 in cells. Falcarindiol induces apoptosis and autophagy. Falcarindiol has anti-inflammatory, antifungal, anticancer and antidiabetic properties . Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N15960

Photoclick cholesterol II	Structural Classification Lipid	Biochemical Assay Reagents
Photoclick cholesterol II is a sterol lipid Cholesterol (HY-N0322) analog that contains a clickable terminal alkyne moiety and a photoactivatable diaziridine group.

Cat. No.	Product Name		Classification

HY-151705

**Alkyne Cholesterol** 1 Publications Verification		Alkynes Labeling and Fluorescence Imaging
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-137018

27-Alkyne cholesterol		Alkynes
27-Alkyne cholesterol is a modified lipid containing an omega-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as click chemistry, in the presence of a copper-containing catalyst. Alkyne cholesterol represents a versatile, sensitive, and easy-to-use tool for tracking cellular cholesterol metabolism and localization as it allows for manifold detection methods including mass spectrometry, and fluorescence microscopy.

HY-W782122

Photoclick cholesterol		Alkynes
Photoclick cholesterol is a sterol lipid cholesterol analog that contains a clickable terminal alkyne moiety and a photoactivatable diaziridine group. Photoclick cholesterol has the ability to photoaffinity label the mitochondrial outer membrane transport protein (TSPO) and is able to specifically bind cholesterol to TSPO. However, using excessive amounts of Photoclick cholesterol will reduce the photolabeling of total mitochondrial proteins and TSPO .

HY-173385

Cholesteryl-PEG1000-Azide		Azide
Cholesteryl-PEG1000-Azide is a lipid that can be used for drug delivery. Cholesteryl-PEG1000-Azide is attached to the cholesterol backbone with a PEG unit on one side and an azide unit on the other side of the PEG. Cholesteryl-PEG1000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .

Cat. No.	Product Name		Classification

HY-151705

**Alkyne Cholesterol** 1 Publications Verification		Cholesterol
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Click Chemistry

Oligonucleotides

Natural
Products