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Results for "

Ah receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (1) Adrenergic Receptor (7) Androgen Receptor (1) Apoptosis (1) Aryl Hydrocarbon Receptor (2) Biochemical Assay Reagents (1) c-Myc (1) Calcium Channel (2) Cytochrome P450 (1) ERK (1) Histamine Receptor (1) iGluR (2) Influenza Virus (2) Interleukin Related (1) Isotope-Labeled Compounds (3) Melatonin Receptor (1) p38 MAPK (1) PD-1/PD-L1 (1) Potassium Channel (2) Prostaglandin Receptor (5) PTHR (1) Reference Standards (4) Sigma Receptor (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (8) Endocrinology (9) Infection (2) Inflammation/Immunology (11) Neurological Disease (5)

By Targets:

Adenosine Receptor (1)

Adrenergic Receptor (7)

Androgen Receptor (1)

Apoptosis (1)

Aryl Hydrocarbon Receptor (2)

Biochemical Assay Reagents (1)

c-Myc (1)

Calcium Channel (2)

Cytochrome P450 (1)

ERK (1)

Histamine Receptor (1)

iGluR (2)

Influenza Virus (2)

Interleukin Related (1)

Isotope-Labeled Compounds (3)

Melatonin Receptor (1)

p38 MAPK (1)

PD-1/PD-L1 (1)

Potassium Channel (2)

Prostaglandin Receptor (5)

PTHR (1)

Reference Standards (4)

Sigma Receptor (1)

By Research Areas:

Cancer (4)

Cardiovascular Disease (8)

Endocrinology (9)

Infection (2)

Inflammation/Immunology (11)

Neurological Disease (5)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15103

AH3960	PTHR Androgen Receptor	Cancer
AH3960 (compound 16c) is an antagonist of androgen receptor. AH3960 binds wild as well as T877 mutant type androgen receptors. AH3960 selectively inhibits T877 with an IC₅₀ value of 0.82 μM. AH3960 also serves as an agonist of *parathyroid hormone receptor-1 (PTHR1)* .

HY-10418

AH 6809 3 Publications Verification	Prostaglandin Receptor	Inflammation/Immunology Endocrinology
AH 6809 is an antagonist of EP and DP receptor, with K_is of 1217, 1150, 1597, and 1415 nM for the cloned human EP₁, EP₂, EP₃-III, and DP receptor respectively. AH 6809 has a K_i of 350 nM for mouse EP₂ receptor .

HY-101358

8-M-PDOT Ah-002	Melatonin Receptor	Neurological Disease
8-M-PDOT (AH-002) is a selective melatonin MT2 receptor agonist. 8-M-PDOT is 5.2-fold selective for MT2 over MT1 receptors. 8-M-PDOT binds human recombinant MT2 and MT2 receptors with pKi values of 8.23 and 8.95 respectively. 8-M-PDOT has anxiolytic-like activity .

HY-10418R

AH 6809 (Standard)	Reference Standards Prostaglandin Receptor	Inflammation/Immunology Endocrinology
AH 6809 (Standard) is the analytical standard of AH 6809. This product is intended for research and analytical applications. AH 6809 is an antagonist of EP and DP receptor, with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively. AH 6809 has a Ki of 350 nM for mouse EP2 receptor .

HY-10419A

AH23848 hemicalcium salt	Prostaglandin Receptor	Cardiovascular Disease
AH23848 hemicalcium salt is a potent, specific and orally active thromboxane receptor blocker. AH23848 hemicalcium salt inhibits platelet deposition .

HY-19641

AH13205	Biochemical Assay Reagents Prostaglandin Receptor	Others
AH13205 is a selective prostanoid *EP₂-receptor* agonist. AH13205 causes concentration-related relaxations of Carbachol (HY-B1208)-contracted trachea. AH13205 causes dose-related protection against Histamine (HY-B1204)-induced increases in respiratory rate .

HY-105027

Sufotidine Ah 25352X	Histamine Receptor	Inflammation/Immunology
Sufotidine (AH 25352X) is a potent competitive antagonist of H2-receptor. Sufotidine has acid inhibitory activity .

HY-115827

AH22921	Prostaglandin Receptor	Others
AH22921 is an EP4 prostaglandin receptor antagonist with the activity of antagonizing the activation of adenylate cyclase by prostaglandins in CHO cells. AH22921 can shift the PGE2 concentration-response curve to the right in CHO cells. It is a non-competitive antagonist that is selective for EP4 receptors and has an antagonistic effect on EP4 receptors in CHO cells, but does not affect the PGE2 concentration-response curve in NPE cells containing EP2 receptors.

HY-W014701R

1,4-Dihydroxy-2-naphthoic acid (Standard)	Reference Standards Aryl Hydrocarbon Receptor Cytochrome P450 Apoptosis Interleukin Related	Neurological Disease Inflammation/Immunology Endocrinology
1,4-Dihydroxy-2-naphthoic acid (Standard) is the analytical standard for 1,4-Dihydroxy-2-naphthoic acid (HY-W014701). 1,4-Dihydroxy-2-naphthoic acid is an orally active aryl hydrocarbon receptor (AhR) agonist and a bifidogenic growth stimulator. 1,4-Dihydroxy-2-naphthoic acid can improve the motor dysfunction in parkinson's disease (PD) model through AhR-dependent and -independent pathways. 1,4-Dihydroxy-2-naphthoic acid exerts anti-inflammatory effects by regulating the gut microbiota (such as promoting the proliferation of Bifidobacterium) and directly regulating the host immune system. 1,4-Dihydroxy-2-naphthoic acid induces apoptosis through G0/G1 cell cycle arrest in human keratinocyte to inhibit psoriasis .

HY-B1108S

Labetalol hydrochloride-d5 Ah-5158 hydrochloride-d₅; Sch-15719W-d₅	Isotope-Labeled Compounds	Cardiovascular Disease Inflammation/Immunology Endocrinology
Labetalol hydrochloride-d₅ (AH-5158 hydrochloride-d₅) is deuterium labeled Labetalol hydrochloride (HY-B1108). Labetalol (AH5158) hydrochloride is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol hydrochloride is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol hydrochloride can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .

HY-W728545

Labetalol-d6 hydrochloride Ah5158-d₆ hydrochloride; Sch-15719W-d₆	Isotope-Labeled Compounds	Cardiovascular Disease Inflammation/Immunology Endocrinology
Labetalol hydrochloride-d₆ (AH-5158 hydrochloride-d₆) is deuterium labeled Labetalol hydrochloride (HY-B1108). Labetalol (AH5158) hydrochloride is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol hydrochloride is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol hydrochloride can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .

HY-B1813A

(±)-Vesamicol hydrochloride 1 Publications Verification (±)-Ah5183 hydrochloride	Sigma Receptor	Neurological Disease
(±)-Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a potent vesicular acetylcholine transport inhibitor with a K_i of 2 nM. (±)-Vesamicol hydrochloride also displays high affinity for σ1 and σ2 receptors with K_is of 26 nM and 34 nM, respectively .

HY-W707640

Salbutamol-d4 Albuterol-d₄; Ah-3365-d₄	Isotope-Labeled Compounds ERK Adrenergic Receptor	Cancer
Salbutamol-d₄ (Albuterol-d₄; AH-3365-d₄) is the deuterium labeled Salbutamol (HY-B1037). Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD) .

HY-105093

N 0861	Adenosine Receptor	Inflammation/Immunology
N-0861 is a novel selective A1 adenosine receptor antagonist. In studies, it has been shown to be able to inhibit the negative conduction effects (prolonged AH interval) and chest pain caused by adenosine, while having no significant effect on the increase in coronary blood flow velocity caused by adenosine. This indicates that N-0861 has the property of selectively inhibiting A1 adenosine receptors .

HY-B1108

Labetalol hydrochloride 4 Publications Verification Ah-5158 hydrochloride; Sch-15719W	Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Labetalol (AH5158) hydrochloride is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol hydrochloride is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol hydrochloride can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .

HY-121383

Labetalol 4 Publications Verification Ah5158; Sch-15719W free base	Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Labetalol (AH5158) is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .

HY-121383R

Labetalol (Standard) Ah5158 (Standard); Sch-15719W free base (Standard)	Reference Standards Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Labetalol (Standard) is the analytical standard of Labetalol. This product is intended for research and analytical applications. Labetalol (AH5158) is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .

HY-B1108R

Labetalol hydrochloride (Standard) 3 Publications Verification Ah-5158 hydrochloride(Standard); Sch-15719W (Standard)	Reference Standards Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Labetalol hydrochloride (Standard) is the analytical standard of Labetalol hydrochloride (HY-B1108). This product is intended for research and analytical applications. Labetalol (AH5158) hydrochloride is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol hydrochloride is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol hydrochloride can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .

HY-N12537A

(2R,3S)-PD-1/PD-L1-IN-38	Aryl Hydrocarbon Receptor PD-1/PD-L1	Cancer
(2R,3S)-PD-1/PD-L1-IN-38 (Compound (±)-13e) is an orally active Ah receptor (AhR) antagonist with in vivo and in vitro anticancer activity. (2R,3S)-PD-1/PD-L1-IN-38 promotes the secretion of INF-γ by CD8 ⁺T cells and inhibits the signal transduction of PD-1/PD-L1 .

HY-12882

Ifenprodil Maximum Cited Publications 10 Publications Verification NP-120; RC-61-91	iGluR Adrenergic Receptor Potassium Channel Calcium Channel Influenza Virus	Infection Neurological Disease
Ifenprodil (NP-120), a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil exerts high affinity at NR1A/NR2B receptors (IC₅₀=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC₅₀=146 μM) . Ifenprodil is an α1 adrenergic receptor antagonist. Ifenprodil inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil has reliable inhibitory effects against A/H1N1 strains (EC₅₀ of 6.6 µM). Ifenprodil has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease .

HY-12882A

Ifenprodil tartrate Maximum Cited Publications 10 Publications Verification NP-120 tartrate; RC-61-91 tartrate	iGluR Adrenergic Receptor Potassium Channel Calcium Channel Influenza Virus	Infection Neurological Disease
Ifenprodil (NP-120) tartrate, a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC₅₀=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC₅₀=146 μM) . Ifenprodil tartrate is an α1 adrenergic receptor antagonist. Ifenprodil tartrate inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has reliable inhibitory effects against A/H1N1 strains (EC₅₀ of 6.6 µM). Ifenprodil tartrate has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil tartrate can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease .

HY-176019

Methylcarbamyl PAF C-8	p38 MAPK c-Myc	Cardiovascular Disease Cancer
Methylcarbamyl PAF C-8 is resistant to the degradation function of platelet-activating factor acetylhydrolase (PAF-AH). It has a half-life of more than 100 minutes in platelet-poor plasma and possesses the activity of inducing platelet aggregation. In NRK-49 cells overexpressing the PAF receptor, Methylcarbamyl PAF C-8 can induce the expression of c-myc and c-fos, and activate mitogen-activated protein kinase (MAPK). Additionally, Methylcarbamyl PAF C-8 can induce cell cycle arrest in the G1 phase. Methylcarbamyl PAF C-8 holds promise for research in the fields of cardiovascular diseases and anti-cancer therapy .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-12882A

Ifenprodil tartrate 5+ Cited Publications NP-120 tartrate; RC-61-91 tartrate	Alkaloids Piperidine Alkaloids Neurological Disease Classification of Application Fields Crassulaceae Source classification Sedum sarmentosum Bunge Plants Disease Research Fields	iGluR Adrenergic Receptor Potassium Channel Calcium Channel Influenza Virus
Ifenprodil (NP-120) tartrate, a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC₅₀=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC₅₀=146 μM) . Ifenprodil tartrate is an α1 adrenergic receptor antagonist. Ifenprodil tartrate inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has reliable inhibitory effects against A/H1N1 strains (EC₅₀ of 6.6 µM). Ifenprodil tartrate has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil tartrate can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease .

HY-W014701R

1,4-Dihydroxy-2-naphthoic acid (Standard)	Microorganisms Ketones, Aldehydes, Acids Source classification	Reference Standards Aryl Hydrocarbon Receptor Cytochrome P450 Apoptosis Interleukin Related
1,4-Dihydroxy-2-naphthoic acid (Standard) is the analytical standard for 1,4-Dihydroxy-2-naphthoic acid (HY-W014701). 1,4-Dihydroxy-2-naphthoic acid is an orally active aryl hydrocarbon receptor (AhR) agonist and a bifidogenic growth stimulator. 1,4-Dihydroxy-2-naphthoic acid can improve the motor dysfunction in parkinson's disease (PD) model through AhR-dependent and -independent pathways. 1,4-Dihydroxy-2-naphthoic acid exerts anti-inflammatory effects by regulating the gut microbiota (such as promoting the proliferation of Bifidobacterium) and directly regulating the host immune system. 1,4-Dihydroxy-2-naphthoic acid induces apoptosis through G0/G1 cell cycle arrest in human keratinocyte to inhibit psoriasis .

HY-N12537A

(2R,3S)-PD-1/PD-L1-IN-38	Ketones, Aldehydes, Acids Labiatae Source classification Samanea saman (Jacq.) Merr. Plants	Aryl Hydrocarbon Receptor PD-1/PD-L1
(2R,3S)-PD-1/PD-L1-IN-38 (Compound (±)-13e) is an orally active Ah receptor (AhR) antagonist with in vivo and in vitro anticancer activity. (2R,3S)-PD-1/PD-L1-IN-38 promotes the secretion of INF-γ by CD8 ⁺T cells and inhibits the signal transduction of PD-1/PD-L1 .

Cat. No.	Compare	Product Name	Species	Source

HY-P704187

	AHR Protein, Human (His) Aryl hydrocarbon receptor; Ah receptor; lass E basic helix-loop-helix protein 76 (bHLHe76); AhR; BHLHE76	Human	E. coli
	AHR Protein, Human (His) is the recombinant human-derived AHR protein, expressed by E. coli, with N-10*His tag.

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Cat. No.	Product Name	Chemical Structure

HY-B1108S

Labetalol hydrochloride-d5
Labetalol hydrochloride-d₅ (AH-5158 hydrochloride-d₅) is deuterium labeled Labetalol hydrochloride (HY-B1108). Labetalol (AH5158) hydrochloride is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol hydrochloride is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol hydrochloride can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .

Labetalol hydrochloride-d5

Labetalol hydrochloride-d₅ (AH-5158 hydrochloride-d₅) is deuterium labeled Labetalol hydrochloride (HY-B1108). Labetalol (AH5158) hydrochloride is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol hydrochloride is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol hydrochloride can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .

HY-W728545

Labetalol-d6 hydrochloride
Labetalol hydrochloride-d₆ (AH-5158 hydrochloride-d₆) is deuterium labeled Labetalol hydrochloride (HY-B1108). Labetalol (AH5158) hydrochloride is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol hydrochloride is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol hydrochloride can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .

Labetalol-d6 hydrochloride

Labetalol hydrochloride-d₆ (AH-5158 hydrochloride-d₆) is deuterium labeled Labetalol hydrochloride (HY-B1108). Labetalol (AH5158) hydrochloride is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol hydrochloride is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol hydrochloride can be used in the study of cardiovascular diseases, such as hypertension during pregnancy .

HY-W707640

Salbutamol-d4
Salbutamol-d₄ (Albuterol-d₄; AH-3365-d₄) is the deuterium labeled Salbutamol (HY-B1037). Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD) .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80378

	*Aryl Hydrocarbon Receptor* Antibody (YA610)** 1 Publications Verification Ah receptor; Aromatic hydrocarbon receptor; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor; BHLHE76; Class E basic helix loop helix protein 76; HGNC:348; AhR_HUMAN.	WB, ICC/IF	Human
	Aryl Hydrocarbon Receptor Antibody (YA610) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Aryl Hydrocarbon Receptor.

HY-P87356

	AIP Antibody (YA7039) Ah receptor interacting protein antibody; Ah receptor-interacting protein antibody; AIP antibody; AIP_HUMAN antibody; ARA 9 antibody; ARA9 antibody; Aryl hydrocarbon receptor interacting protein antibody; Aryl-hydrocarbon receptor-interacting protein antibody; fa03h10 antibody; FKBP 16 antibody	WB	Human, Mouse, Rat
	AIP Antibody (YA7039) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AIP.

HY-P82417

	*Aryl Hydrocarbon Receptor* Antibody (YA2162)** Ah receptor; AhR; Class E basic helix-loop-helix protein 76; bHLHe76; AhR	WB	Human
	Aryl Hydrocarbon Receptor Antibody (YA2162) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Aryl Hydrocarbon Receptor.

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