Active pharmaceutical ingredient

By Targets:	5-HT Receptor (2) Apoptosis (2) Autophagy (1) Biochemical Assay Reagents (6) Drug Intermediate (1) Endogenous Metabolite (2) mAChR (1) Microtubule/Tubulin (1) NF-κB (1) Phosphodiesterase (PDE) (1) Photosensitizer (1) Reactive Oxygen Species (ROS) (1) TSH Receptor (1)
By Research Areas:	Cancer (3) Infection (1) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (3)
Oligonucleotides:	Preservatives (1) Thickeners (2) Fillers (1) Flavoring Agents (1) Emulsifiers (1) Surfactants (1) Freeze-drying Protective Agents (1) Sweetening Agents (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-78509

Dibenzosuberone	Biochemical Assay Reagents Drug Intermediate	Neurological Disease
Dibenzosuberone belongs to the family of tricyclic antidepressant drugs, commonly referred to as Tricyclic antidepressants (TCAs), and is widely used in research on migraine, tension headaches, anxiety disorders, and schizophrenia. Dibenzosuberone is also a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs), such as Amitriptyline (HY-B0527), Nortriptyline (HY-118620), Noxiptiline or Cyproheptadine (HY-B1622) .

HY-W069177

Benzylthiouracil 6-Benzyl-2-thiouracil	TSH Receptor	Others
Benzylthiouracil is an active pharmaceutical ingredient against hyperthyroidism .

HY-W115716

Sorbitan trioleate	Biochemical Assay Reagents	Others
Sorbitan trioleate is an orally active nonionic surfactant with low toxicity (LD≥200 mg/kg). Sorbitan trioleate can be used as an excipient, such as surfactant, emulsifier, lubricant, wetting agent, dispersant, thickener, defoamer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-Y1316

Sodium benzoate 2 Publications Verification	Biochemical Assay Reagents NF-κB Apoptosis	Inflammation/Immunology Cancer
Sodium benzoate is an orally active pharmaceutical excipient, such as an antibacterial agent, preservative, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.Sodium benzoate activates NF-κB and induces Apoptosis. Sodium benzoate induces immune suppression and produces reproductively toxic. Sodium benzoate can be used for colon cancer and immune disease research .

HY-40351

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine	Biochemical Assay Reagents	Others
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a key intermediate when preparing active pharmaceutical ingredient .

HY-W051271

Titanium(IV) oxide Titanium dioxide	Photosensitizer Reactive Oxygen Species (ROS)	Others
Titanium(IV) oxide is a photosensitizer and photocatalyst. Titanium(IV) oxide can be used as a pharmaceutical excipient such as a flow aid, coating agent, sunscreen, colorant, etc. Pharmaceutical excipients or pharmaceutical excipients refer to other chemical substances used in the pharmaceutical process other than the drug ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations that can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism and elimination (ADME) process of co-administered drugs. Titanium(IV) oxide can use light energy to generate electron-hole pairs to degrade pollutants. Photons excite electrons in TiO₂ to generate active oxygen species (such as ·OH and ·O₂ ^-), thereby oxidizing and mineralizing pollutants such as organic compounds and heavy metals. TiO₂ can be used in the research of environmental remediation fields such as water treatment, air purification and self-cleaning materials .

HY-N1132

D-(+)-Trehalose Maximum Cited Publications 7 Publications Verification D-Trehalose; α,α-Trehalose	Endogenous Metabolite	Metabolic Disease
D-(+)-Trehalose (α,α-Trehalose) is an orally active disaccharide, showing anti-desiccant and cryopreservative activities. D-(+)-Trehalose acts as an osmolyte, and stress protectant and helps in the storage and transport of carbon. D-(+)-Trehalose can be used as a food ingredient and pharmaceutical excipient .

HY-155819

M3/PDE4 modulator-1	mAChR Phosphodiesterase (PDE)	Inflammation/Immunology
M3/PDE4 modulator-1 (compound 10f) is a bifunctional molecule that is an M3 mAChR antagonist and a PDE4 inhibitor. M3/PDE4 modulator-1 (10-1000 nM/kg; iv) reduces cysteine eosinophil influx in the OVA rat model .

HY-158569

SAR114137	Endogenous Metabolite	Others
SAR114137 is a highly effective drug with potent biological activity. SAR114137 exhibits altered amorphous content characteristics during physical processing of the crystalline active pharmaceutical ingredient. The amorphous API content of SAR114137 is significantly reduced when processed by different jet grinding techniques. SAR114137 exhibits good chemical stability in pharmaceutical formulations .

HY-122407

Hexadecyltrimethylammonium hydroxide Cetyltrimethylammonium hydroxide	Biochemical Assay Reagents	Others
Hexadecyltrimethylammonium hydroxide, a quaternary ammonium compound, is commonly used as an emulsifier, detergent, and surfactant in various industrial processes, especially in the production of cosmetics, pharmaceuticals, and textiles. Hexadecyltrimethylammonium hydroxide has unique chemical properties that make it an active ingredient in many applications requiring strong surface activity and solubility.

HY-167663

Ebalzotan	5-HT Receptor	Neurological Disease
Ebalzotan is a 5-HT1A receptor agonist with activity in the study of depression. Ebalzotan can serve as a precursor to important active pharmaceutical ingredients. The synthesis of Ebalzotan involves a multi-enzyme catalyzed reduction reaction to obtain saturated primary or secondary alcohols in high yields and high enantioselectivity .

HY-W115746

Ethyl cellulose Ethyl cellulose N-200	Biochemical Assay Reagents	Infection Cancer
Ethyl cellulose is a derivative of cellulose. Ethyl cellulose is a non-toxic, biodegradable polymer. Ethyl cellulose has unique properties such as oil gel formation, active ingredient delivery and film formation. Ethyl cellulose can be used as a pharmaceutical excipient, such as a coating agent, flavoring agent, tablet filler, etc. Ethyl cellulose can be used to prepare nanoparticles for active compound delivery .

HY-167663A

(S)-Ebalzotan	5-HT Receptor	Neurological Disease
(S)-Ebalzotan is the S-form of Ebalzotan (HY-167663). Ebalzotan is a 5-HT1A receptor agonist with activity in the study of depression. Ebalzotan can serve as a precursor to important active pharmaceutical ingredients. The synthesis of Ebalzotan involves a multi-enzyme catalyzed reduction reaction to obtain saturated primary or secondary alcohols in high yields and high enantioselectivity .

HY-P99974

Nab-Paclitaxel 1 Publications Verification Nanoparticle albumin-bound Paclitaxel; Nanoparticle albumin-bound ABI-007	Microtubule/Tubulin Apoptosis Autophagy	Cancer
Nab-Paclitaxel (Nanoparticle albumin-bound Paclitaxel) is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015). Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel, in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug. Nab-Paclitaxel is a solvent-free taxane with higher response rates and improved tolerability. Nab-Paclitaxel displays less toxicity and greater antitumor activity. Nab-Paclitaxel is more readily available for tumor cell uptake in three rhabdomyosarcoma, seven neuroblastoma cell lines, and one ostersarcoma cell line Nab-Paclitaxel can be studied in cancer research for example breast cancer and solid tumors. (The product specifications below only indicate the effective content of Paditaxel, the actual albumin quality depends on the batch; the ratio of each ingredient in this product is Paditaxel: albumin -1:7~1:11) .

Cat. No.	Product Name

HY-L096

Inactive Ingredient Library	179 compounds
An inactive ingredient is any component of a drug product other than the active ingredient. Inactive ingredients are added during the manufacturing process of pharmaceutical products such as tablets, capsules, suppositories, and injections. In new drug development, once an inactive ingredient has appeared in an approved drug product for a particular route of administration, the inactive ingredient is not considered new and may require a less extensive review the next time it is included in a new drug product. MCE offers a unique collection of 179 inactive ingredients, which only contain inactive ingredients of the final dosage forms of the drug. MCE Inactive Ingredient library is a powerful tool for aiding in the development of the drug and saving unnecessary time.

Inactive Ingredient Library

179 compounds

An inactive ingredient is any component of a drug product other than the active ingredient. Inactive ingredients are added during the manufacturing process of pharmaceutical products such as tablets, capsules, suppositories, and injections. In new drug development, once an inactive ingredient has appeared in an approved drug product for a particular route of administration, the inactive ingredient is not considered new and may require a less extensive review the next time it is included in a new drug product.

MCE offers a unique collection of 179 inactive ingredients, which only contain inactive ingredients of the final dosage forms of the drug. MCE Inactive Ingredient library is a powerful tool for aiding in the development of the drug and saving unnecessary time.

Cat. No.	Product Name	Type

HY-40351

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine	Biochemical Assay Reagents
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a key intermediate when preparing active pharmaceutical ingredient .

HY-122407

Hexadecyltrimethylammonium hydroxide Cetyltrimethylammonium hydroxide	Surfactants
Hexadecyltrimethylammonium hydroxide, a quaternary ammonium compound, is commonly used as an emulsifier, detergent, and surfactant in various industrial processes, especially in the production of cosmetics, pharmaceuticals, and textiles. Hexadecyltrimethylammonium hydroxide has unique chemical properties that make it an active ingredient in many applications requiring strong surface activity and solubility.

Hexadecyltrimethylammonium hydroxide

Cetyltrimethylammonium hydroxide

Surfactants

Hexadecyltrimethylammonium hydroxide, a quaternary ammonium compound, is commonly used as an emulsifier, detergent, and surfactant in various industrial processes, especially in the production of cosmetics, pharmaceuticals, and textiles. Hexadecyltrimethylammonium hydroxide has unique chemical properties that make it an active ingredient in many applications requiring strong surface activity and solubility.

Cat. No.	Product Name	Target	Research Area

HY-P99974

Nab-Paclitaxel 1 Publications Verification Nanoparticle albumin-bound Paclitaxel; Nanoparticle albumin-bound ABI-007	Microtubule/Tubulin Apoptosis Autophagy	Cancer
Nab-Paclitaxel (Nanoparticle albumin-bound Paclitaxel) is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015). Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel, in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug. Nab-Paclitaxel is a solvent-free taxane with higher response rates and improved tolerability. Nab-Paclitaxel displays less toxicity and greater antitumor activity. Nab-Paclitaxel is more readily available for tumor cell uptake in three rhabdomyosarcoma, seven neuroblastoma cell lines, and one ostersarcoma cell line Nab-Paclitaxel can be studied in cancer research for example breast cancer and solid tumors. (The product specifications below only indicate the effective content of Paditaxel, the actual albumin quality depends on the batch; the ratio of each ingredient in this product is Paditaxel: albumin -1:7~1:11) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1132

D-(+)-Trehalose 5+ Cited Publications D-Trehalose; α,α-Trehalose	Polysaccharides Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite
D-(+)-Trehalose (α,α-Trehalose) is an orally active disaccharide, showing anti-desiccant and cryopreservative activities. D-(+)-Trehalose acts as an osmolyte, and stress protectant and helps in the storage and transport of carbon. D-(+)-Trehalose can be used as a food ingredient and pharmaceutical excipient .

Cat. No.	Product Name		Classification

HY-W115716

Sorbitan trioleate		Emulsifiers Thickeners Surfactants
Sorbitan trioleate is an orally active nonionic surfactant with low toxicity (LD≥200 mg/kg). Sorbitan trioleate can be used as an excipient, such as surfactant, emulsifier, lubricant, wetting agent, dispersant, thickener, defoamer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-Y1316

Sodium benzoate 2 Publications Verification		Preservatives
Sodium benzoate is an orally active pharmaceutical excipient, such as an antibacterial agent, preservative, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.Sodium benzoate activates NF-κB and induces Apoptosis. Sodium benzoate induces immune suppression and produces reproductively toxic. Sodium benzoate can be used for colon cancer and immune disease research .

HY-N1132

D-(+)-Trehalose 5+ Cited Publications D-Trehalose; α,α-Trehalose		Sweetening Agents Thickeners Flavoring Agents Freeze-drying Protective Agents
D-(+)-Trehalose (α,α-Trehalose) is an orally active disaccharide, showing anti-desiccant and cryopreservative activities. D-(+)-Trehalose acts as an osmolyte, and stress protectant and helps in the storage and transport of carbon. D-(+)-Trehalose can be used as a food ingredient and pharmaceutical excipient .

HY-W115746

Ethyl cellulose Ethyl cellulose N-200		Fillers
Ethyl cellulose is a derivative of cellulose. Ethyl cellulose is a non-toxic, biodegradable polymer. Ethyl cellulose has unique properties such as oil gel formation, active ingredient delivery and film formation. Ethyl cellulose can be used as a pharmaceutical excipient, such as a coating agent, flavoring agent, tablet filler, etc. Ethyl cellulose can be used to prepare nanoparticles for active compound delivery .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Inhibitory Antibodies

Natural
Products

Oligonucleotides

Name
Email *

	Sorry, but the email address you supplied was invalid.

Active pharmaceutical ingredient

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Inhibitory Antibodies

NaturalProducts

Oligonucleotides

Natural
Products