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Results for "

ATG16L1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Recombinant Proteins

2

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100008
    Peretinoin
    5 Publications Verification

    NIK333

    		 RAR/RXR SphK Autophagy HCV Infection Cancer
    Peretinoin is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as retinoid X receptor (RXR) and retinoic acid receptor (RAR). Peretinoin reduces the mRNA level of sphingosine kinase 1 (SPHK1) in vitro by downregulating a transcription factor, Sp1 . Peretinoin prevents the progression of non-alcoholic steatohepatitis (NASH) and the development of hepatocellular carcinoma (HCC) through activating the autophagy pathway by increased Atg16L1 expression . Peretinoin inhibits HCV RNA amplification and virus release by altering lipid metabolism with a EC50 of 9 μM .
    Peretinoin
  • HY-170998
    ATG16L1 stabilizer-1

    		Autophagy Inflammation/Immunology
    ATG16L1 stabilizer-1 (compound A3B) is an FKBP12-independent ATG16L1 stabilizer that promotes cellular Autophagy. ATG16L1 stabilizer-1 inhibits ATG16L1 with an EC50 of 12.1 μM in the presence or absence of FKBP12. ATG16L1 stabilizer-1 alone induces GFP-LC3 puncta formation to a small extent with an EC50 of 12.0 μM .
    ATG16L1 stabilizer-1
  • HY-RS26329
    Atg16l1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Atg16l1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Atg16l1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Atg16l1 Rat Pre-designed siRNA Set A
    Atg16l1 Rat Pre-designed siRNA Set A
  • HY-RS01143
    ATG16L1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ATG16L1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATG16L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ATG16L1 Human Pre-designed siRNA Set A
    ATG16L1 Human Pre-designed siRNA Set A
  • HY-RS19832
    Atg16l1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Atg16l1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atg16l1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Atg16l1 Mouse Pre-designed siRNA Set A
    Atg16l1 Mouse Pre-designed siRNA Set A
  • HY-100008R
    Peretinoin (Standard)

    NIK333 (Standard)

    		 Reference Standards RAR/RXR SphK Autophagy HCV Infection Cancer
    Peretinoin (Standard) is the analytical standard of Peretinoin. This product is intended for research and analytical applications. Peretinoin is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as retinoid X receptor (RXR) and retinoic acid receptor (RAR). Peretinoin reduces the mRNA level of sphingosine kinase 1 (SPHK1) in vitro by downregulating a transcription factor, Sp1[1]. Peretinoin prevents the progression of non-alcoholic steatohepatitis (NASH) and the development of hepatocellular carcinoma (HCC) through activating the autophagy pathway by increased Atg16L1 expression[2]. Peretinoin inhibits HCV RNA amplification and virus release by altering lipid metabolism with a EC50 of 9 μM[3].
    Peretinoin (Standard)

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