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Results for "

ABCG1

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-123148
    IMB-808

    		LXR Inflammation/Immunology
    IMB-808 is a potent LXRα/β dual agonist with EC50 values of 0.53 μM and 0.15 μM (0.15 μM, using GAL4-pGL4-luc reporter plasmid) for LXRβ and LXRα, respectively. IMB-808 promotes expression of genes related to reverse cholesterol transport (ABCA1 and ABCG1). IMB-808 can be used as a promising agent for the prospective treatment of atherosclerosis research [1].
    IMB-808
  • HY-18282
    AZ876

    		LXR Cardiovascular Disease Metabolic Disease Cancer
    AZ876 is a selective, orally active agonist of liver X receptor (LXRα/β) (Ki=0.007 μM [LXRα, human], 0.011 μM [LXRβ, human]. AZ876 induces the expression of target genes such as ABCA1 and ABCG1, promotes reverse cholesterol transport (RCT) and regulates lipid metabolism and anti-inflammatory effects. AZ876 increases cardiac polyunsaturated fatty acid levels, reduces myocardial fibrosis, and reduces lesion area and monocyte adhesion in atherosclerosis models. AZ876 can be used in cardiovascular disease research, such as preventing and treating β-adrenergic-induced cardiac diastolic dysfunction and inhibiting the progression of atherosclerosis [1] .
    AZ876
  • HY-RS23956
    Abcg1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Abcg1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Abcg1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Abcg1 Rat Pre-designed siRNA Set A
    Abcg1 Rat Pre-designed siRNA Set A
  • HY-RS00076
    ABCG1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ABCG1 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ABCG1 Human Pre-designed siRNA Set A
    ABCG1 Human Pre-designed siRNA Set A
  • HY-RS17499
    Abcg1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Abcg1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Abcg1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Abcg1 Mouse Pre-designed siRNA Set A
    Abcg1 Mouse Pre-designed siRNA Set A
  • HY-W674245
    10-Hydroxyhexadecanoic acid

    		ATP-binding cassette (ABC) transporters Cardiovascular Disease
    10-Hydroxyhexadecanoic acid is a hydroxy fatty acid found in Camembert cheese. 10-Hydroxyhexadecanoic acid can promote cholesterol efflux from ABCA1 and ABCG1, preventing the accumulation of excess cholesterol in cells. 10-Hydroxyhexadecanoic acid can be used in anti-atherosclerosis research [1].
    10-Hydroxyhexadecanoic acid
  • HY-121671
    TBTC

    		RAR/RXR Neurological Disease
    TBTC is a selective agonist with the activity of improving behavioral deficits in Alzheimer's disease model mice. TBTC can effectively activate the heterodimerization of RXRα with LXRα or PPARγ. TBTC stimulates the expression of apoE, ABCA1, and ABCG1 genes and reduces Aβ content in cells and animal models [1].
    TBTC
  • HY-18282R
    AZ876 (Standard)

    		LXR Cardiovascular Disease Metabolic Disease Cancer
    AZ876 (Standard) is the analytical standard of AZ876. This product is intended for research and analytical applications. AZ876 is a selective, orally active agonist of liver X receptor (LXRα/β) (Ki=0.007 μM [LXRα, human], 0.011 μM [LXRβ, human]. AZ876 induces the expression of target genes such as ABCA1 and ABCG1, promotes reverse cholesterol transport (RCT) and regulates lipid metabolism and anti-inflammatory effects. AZ876 increases cardiac polyunsaturated fatty acid levels, reduces myocardial fibrosis, and reduces lesion area and monocyte adhesion in atherosclerosis models. AZ876 can be used in cardiovascular disease research, such as preventing and treating β-adrenergic-induced cardiac diastolic dysfunction and inhibiting the progression of atherosclerosis [1] .
    AZ876 (Standard)

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