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7-amino-4-methylcoumarin

" in MedChemExpress (MCE) Product Catalog:

46

Inhibitors & Agonists

6

Fluorescent Dye

1

Biochemical Assay Reagents

42

Peptides

2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0027
    7-Amino-4-methylcoumarin

    Coumarin 120; AMC

    		 Fluorescent Dye Antibiotic Fungal Infection
    7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively.
    7-Amino-4-methylcoumarin
  • HY-D0025
    7-Amino-4-methylcoumarin-3-acetic acid

    		Fluorescent Dye Others
    7-Amino-4-methylcoumarin-3-acetic acid is a fluorescent protein labelling agent. 7-Amino-4-methylcoumarin-3-acetic acid emits in the blue region (440-460 nm) on activation with UV light (350 nm) .
    7-Amino-4-methylcoumarin-3-acetic acid
  • HY-P4417A
    Ac-IEPD-AMC TFA

    		Fluorescent Dye Others
    Ac-IEPD-AMC TFA is a fluorescent substrate used to measure protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC fluoresces under UV light irradiation and can emit fluorescent signals .
    Ac-IEPD-AMC TFA
  • HY-D0027R
    7-Amino-4-methylcoumarin (Standard)

    		Fluorescent Dye Antibiotic Fungal Infection
    7-Amino-4-methylcoumarin (Standard) is the analytical standard of 7-Amino-4-methylcoumarin. This product is intended for research and analytical applications. 7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively. [4]
    7-Amino-4-methylcoumarin (Standard)
  • HY-D0002
    7-Amino-4-methylcoumarin hydrogensulfate

    Coumarin 120 hydrogensulfate; AMC hydrogensulfate

    		 Fluorescent Dye Others
    7-Amino-4-methylcoumarin hydrogensulfate (Coumarin 120 hydrogensulfate; AMC hydrogensulfate) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    7-Amino-4-methylcoumarin hydrogensulfate
  • HY-W776972
    N-d-Biotinyl-7-amino-4-methylcoumarin

    		Biochemical Assay Reagents Others
    N-d-Biotinyl-7-amino-4-methylcoumarin is a biochemical reagent.
    N-d-Biotinyl-7-amino-4-methylcoumarin
  • HY-P4417
    Ac-IEPD-AMC

    		Fluorescent Dye Others
    Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
    Ac-IEPD-AMC
  • HY-P4419
    Boc-Asp(OBzl)-Pro-Arg-AMC

    		Fluorescent Dye Others
    Boc-Asp(OBzl)-Pro-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). The excitation and emission wavelengths are 351 nm and 430 nm, respectively .
    Boc-Asp(OBzl)-Pro-Arg-AMC
  • HY-P4408
    Ac-Arg-Gly-Lys-AMC

    		Fluorescent Dye Others
    Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
    Ac-Arg-Gly-Lys-AMC
  • HY-P4323
    Boc-Gln-Arg-Arg-AMC

    		Fluorescent Dye Others
    Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
    Boc-Gln-Arg-Arg-AMC
  • HY-P4323A
    Boc-Gln-Arg-Arg-AMC acetate

    		Fluorescent Dye Others
    Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
    Boc-Gln-Arg-Arg-AMC acetate
  • HY-P4419A
    Boc-Asp(OBzl)-Pro-Arg-AMC acetate

    		Fluorescent Dye Others
    Boc-Asp(OBzl)-Pro-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC acetate undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
    Boc-Asp(OBzl)-Pro-Arg-AMC acetate
  • HY-P4416
    Ac-Gly-Ala-Lys(Ac)-AMC

    		Fluorescent Dye Others
    Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Gly-Ala-Lys(Ac)-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
    Ac-Gly-Ala-Lys(Ac)-AMC
  • HY-P4443
    Ac-GAK-AMC

    		Fluorescent Dye Others
    Ac-GAK-AMC is a fluorescent substrate that can be used to measure protease activity. AMC (7-amino-4-methylcoumarin) is a fluorescent group. In the presence of protease, the protease will hydrolyze Ac-GAK-AMC into a fluorescent product .
    Ac-GAK-AMC
  • HY-160289
    ARI-3144

    		FAP Cancer
    ARI-3144 is an excellent and specific substrate for fibroblast activation protein (FAP). ARI-3144 is usually coupled with the fluorophore 7-Amino-4-methylcoumarin (HY-D0027) (AMC) for detection and quantification of FAP .
    ARI-3144
  • HY-P4331
    Boc-Gln-Gly-Arg-AMC

    		Fluorescent Dye Ser/Thr Protease Cardiovascular Disease
    Boc-Gln-Gly-Arg-AMC is a fluorogenic substrate for factor XIIa and trypsin. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .
    Boc-Gln-Gly-Arg-AMC
  • HY-P5202
    H-Gly-Gly-Arg-AMC

    		Amino Acid Derivatives Others
    H-Gly-Gly-Arg-AMC is a fluorogenic peptidyl-AMC substrate containing C-terminal 7-amino-4-methylcoumarin (AMC). H-Gly-Gly-Arg-AMC is a suitable for monitoring continuous thrombin generation (TGT) .
    H-Gly-Gly-Arg-AMC
  • HY-P2176
    Z-LRGG-AMC

    Z-Leu-Arg-Gly-Gly-AMC

    		 Biochemical Assay Reagents Others
    Z-LRGG-AMC (Z-Leu-Arg-Gly-Gly-AMC) is a fluorescent substrate that hydrolyzes and releases free fluorescent 7-amino-4-methylcoumarin (AMC). Detection wavelength of AMC: Ex/Em=360/460 nm .
    Z-LRGG-AMC
  • HY-P4333
    Boc-Glu(OBzl)-Gly-Arg-AMC

    		Fluorescent Dye Cardiovascular Disease
    Boc-Glu(OBzl)-Gly-Arg-AMC is a fluorogenic substrate for factors IXa and XIIa. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .
    Boc-Glu(OBzl)-Gly-Arg-AMC
  • HY-P4332
    Boc-Glu(OBzl)-Ala-Arg-AMC

    		Fluorescent Dye Ser/Thr Protease Cardiovascular Disease
    Boc-Glu(OBzl)-Ala-Arg-AMC is a fluorogenic substrate for coagulation factor XIa and trypsin. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .
    Boc-Glu(OBzl)-Ala-Arg-AMC
  • HY-P3110
    Ac-DNLD-AMC

    		Fluorescent Dye Others
    Ac-WLA-AMC is a fluorogenic substrate of caspase-3. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity .
    Ac-DNLD-AMC
  • HY-P2176A
    Z-LRGG-AMC TFA

    Z-Leu-Arg-Gly-Gly-AMC TFA

    		 Fluorescent Dye Others
    Z-LRGG-AMC TFA is the trifluoroacetate salt of Z-LRGG-AMC (HY-P2176). Z-LRGG-AMC TFA is a fluorogenic substrate for isopeptidase T. Upon cleavage of Z-LRGG-AMC TFA by isopeptidase T, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify isopeptidase T activity (Ex/Em : 360/460 nm) .
    Z-LRGG-AMC TFA
  • HY-W927376
    Boc-Val-Arg-AMC

    		Fluorescent Dye Others
    Boc-Val-Arg-AMC is a synthetic peptide compound. As a specific fluorescent substrate, Boc-Val-Arg-AMC can be specifically cleaved by specific enzymes, especially thrombin, to release a fluorescent molecule AMC (7-amino-4-methylcoumarin), which can be used to monitor thrombin activity. Boc-Val-Arg-AMC can be used to detect thrombin activity in plasma samples .
    Boc-Val-Arg-AMC
  • HY-P10828
    MAPI

    		Virus Protease Infection Inflammation/Immunology
    MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .
    MAPI
  • HY-P1003
    Ac-DEVD-AMC
    4 Publications Verification

    		 Fluorescent Dye Others
    Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
    Ac-DEVD-AMC
  • HY-P2075
    EMD 55068

    		Renin Endocrinology
    EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .
    EMD 55068
  • HY-P2336A
    CCZ01048 TFA
    2 Publications Verification

    		 Melanocortin Receptor Cancer
    CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
    CCZ01048 TFA
  • HY-P1108A
    Astressin 2B TFA

    		CFTR Others
    Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC50 values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B TFA antagonizes CRF2-mediated inhibition of gastric emptying .
    Astressin 2B TFA
  • HY-P1108
    Astressin 2B

    		CFTR Others
    Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC50 values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B antagonizes CRF2-mediated inhibition of gastric emptying .
    Astressin 2B
  • HY-P10472
    Azaline B

    		GnRH Receptor Endocrinology
    Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
    Azaline B
  • HY-P4757
    N1-Glutathionyl-spermidine disulfide

    		Parasite Others
    N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
    N1-Glutathionyl-spermidine disulfide
  • HY-P10341
    ZP3022

    		GCGR Metabolic Disease
    ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .
    ZP3022
  • HY-P2592
    Ro 23-7014

    		Cholecystokinin Receptor Others
    Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .
    Ro 23-7014
  • HY-P4521
    Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt

    		MMP Others
    Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt is a MMP12 substrate, and can be used to detect MMP12 enzyme activity .
    Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt
  • HY-P10876
    mcK6A1

    		Amyloid-β Neurological Disease
    mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .
    mcK6A1
  • HY-P3066
    SKF 100398

    d(CH2)5Tyr(Et)VAVP

    		 Vasopressin Receptor Metabolic Disease
    SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
    SKF 100398
  • HY-P4146
    Survodutide

    BI 456906

    		 GLP Receptor GCGR Metabolic Disease
    Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
    Survodutide
  • HY-P4146A
    Survodutide TFA

    BI 456906 TFA

    		 GLP Receptor GCGR Metabolic Disease
    Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
    Survodutide TFA
  • HY-125628
    Kahalalide A

    		Endogenous Metabolite Infection
    Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .
    Kahalalide A
  • HY-P2434
    AP102

    		Somatostatin Receptor Neurological Disease Metabolic Disease Cancer
    AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .
    AP102
  • HY-P10272
    Rusfertide

    PTG-300

    		 Ferroportin Others
    Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .
    Rusfertide
  • HY-A0248A
    Polymyxin B1
    1 Publications Verification

    		 Bacterial Infection
    Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
    Polymyxin B1
  • HY-P5362A
    NODAGA-LM3 TFA

    		Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor Cancer
    NODAGA-LM3 TFA can be labeled by 68Ga for PET imaging. 68Ga-NODAGA-LM3 TFA is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas. NODAGA-LM3 TFA can be labeled with [68Ga] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
    NODAGA-LM3 TFA
  • HY-P5362
    NODAGA-LM3

    		Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor Cancer
    NODAGA-LM3 can be labeled by 68Ga for PET imaging. 68Ga-NODAGA-LM3 is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas. NODAGA-LM3 can be labeled with [68Ga] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
    NODAGA-LM3
  • HY-105168
    TAK 044

    		Endothelin Receptor Cardiovascular Disease
    TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
    TAK 044
  • HY-P10563
    Noraramtide

    BHV-1100

    		 CD38 Cancer
    Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
    Noraramtide

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