Search Result

Results for "

6PGD

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA/RNA Synthesis (1) Endogenous Metabolite (1) NADPH Oxidase (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (2) Metabolic Disease (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

6PGD-IN-1 1-Hydroxy-8-methoxyanthraquinone	Endogenous Metabolite	Cancer
6PGD-IN-1 (compound S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD). IC₅₀ and K_d the value of 17.8μM and 17.1 μM respectively. 6PGD-IN-1 has antitumor activity .

G6PD activator AG1 5+ Cited Publications	NADPH Oxidase	Metabolic Disease
G6PD activator AG1 is a potent and selective glucose-6-phosphate dehydrogenase (G6PD) agonist with an EC50 of 3 μM. G6PD is an oxidoreductase that catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconolactone and the simultaneous reduction of NAD phosphate (NADP) to reduced NADP (NADPH). G6PD activator AG1 can reduce hemolysis of human erythrocytes .

6PGD-IN-2	DNA/RNA Synthesis	Cancer
6PGD-IN-2 is an uncompetitive 6-phosphogluconate dehydrogenase (6PGD) inhibitor with an IC₅₀ of 5.1 μM. 6PGD-IN-2 disrupts 6PGD oligomerization in a substrate-dependent manner. 6PGD-IN-2 results in a decrease of NADPH and Ru-5-P production as well as DNA synthesis in A549 cells. 6PGD-IN-2 can used for the studies of non-small cell carcinoma and liver cancer .

PGD Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PGD Human Pre-designed siRNA Set A contains three designed siRNAs for PGD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PGD Human Pre-designed siRNA Set A PGD Human Pre-designed siRNA Set A

Cat. No.	Compare	Product Name	Species	Source

	PGD Protein, Human (His) 6-phosphogluconate dehydrogenase, decarboxylating; PGD; PGDH	Human	E. coli
	PGD Protein is crucial in cellular metabolism, catalyzing the oxidative decarboxylation of 6-phosphogluconate. This process yields ribulose 5-phosphate, releases CO(2), and simultaneously reduces NADP to NADPH, contributing to essential cellular redox balance. The enzyme's functionality underscores its significance in maintaining cellular homeostasis and participating in key metabolic pathways. PGD Protein, Human (His) is the recombinant human-derived PGD protein, expressed by E. coli , with N-His labeled tag.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

PGD Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PGD Human Pre-designed siRNA Set A contains three designed siRNAs for PGD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Name
Email *

	Sorry, but the email address you supplied was invalid.