Search Result
Results for "
2-Ar-1,2,3-triazole
" in MedChemExpress (MCE) Product Catalog:
14
Biochemical Assay Reagents
16
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-Y0219R
-
|
s-triazole (Standard); Pyrrodiazole (Standard)
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Biochemical Assay Reagents
Reference Standards
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Others
|
|
1,2,4-Triazole (Standard) is the analytical standard of 1,2,4-Triazole. This product is intended for research and analytical applications. 1,2,4-Triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-Y0219
-
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s-triazole; Pyrrodiazole
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Biochemical Assay Reagents
|
Others
|
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1,2,4-Triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
-
- HY-Y0219A
-
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s-triazole sodium; Pyrrodiazole sodium
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Biochemical Assay Reagents
|
Infection
|
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1,2,4-Triazole (sodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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-
-
- HY-W113615
-
-
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- HY-107870
-
-
-
- HY-W012991
-
|
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Biochemical Assay Reagents
|
Others
|
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1,2-Dihydro-3H-1,2,4-triazole-3-thione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
-
- HY-141941S
-
-
-
- HY-W040960R
-
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Reference Standards
|
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2H-1,2,4-Triazole-3-carboxamide (Standard) is the analytical standard of 2H-1,2,4-Triazole-3-carboxamide. This product is intended for research and analytical applications.
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-
-
- HY-169368
-
-
-
- HY-174304
-
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Drug-Linker Conjugates for ADC
|
Cancer
|
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Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide is a drug-linker conjugate for ADC. Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide consists of a Triptolide (HY-32735) and a stable and cleavable linker (Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-Cl) (HY-174810). Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide can be used for synthesis of antibody-drug conjugates (ADC) .
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-
-
- HY-W007685
-
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Biochemical Assay Reagents
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Others
|
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Methyl 1H-1,2,4-triazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
-
- HY-W331786
-
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Bacterial
|
Infection
|
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Ipconazole is a triazole fungicide that can be used for treating rice seed .
|
-
-
- HY-163789
-
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ADC Linker
|
Cancer
|
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Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
-
- HY-WAA0156
-
|
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Drug Intermediate
|
Others
|
|
1-(Pyrrolidin-3-yl)-1H-1,2,4-triazole oxalate is a drug intermediate for synthesis of various active compounds.
|
-
-
- HY-W586475
-
|
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Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
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Fluorescein-triazole-PEG5-DOTA is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
|
-
-
- HY-46369
-
|
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DNA/RNA Synthesis
|
Others
|
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1-p-Chlorobenzyl-1,2,3-triazole-5′-O-DMT-dU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W098127S
-
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Isotope-Labeled Compounds
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Others
|
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Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate-d2 is the deuterium labeled Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate .
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-
-
- HY-W331786R
-
|
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Reference Standards
Bacterial
|
Infection
|
|
Ipconazole (Standard) is the analytical standard of Ipconazole. This product is intended for research and analytical applications. Ipconazole is a triazole fungicide that can be used for treating rice seed .
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-
-
- HY-168006
-
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p97
ATP Synthase
|
Cancer
|
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NSC819701 is a triazole inhibitor of the p97 ATPase. NSC819701 inhibits the activity of p97 ATPase by binding to a specific site of p97 .
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- HY-W019852
-
|
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Fungal
|
Infection
|
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Flutriafol is a triazole fungicide with broad spectrum fungicidal activity.
|
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- HY-B2058
-
|
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Fungal
|
Infection
|
|
Triticonazole is a triazole pesticide. Triticonazole is an azole fungicide and shows endocrine disrupting activities .
|
-
-
- HY-168005
-
|
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p97
ATP Synthase
|
Cancer
|
|
NSC799462 is a triazole inhibitor of p97 ATPase. NSC799462 inhibits p97 ATPase activity (IC50 = 15 nM) by binding to a specific site on p97 and causing local changes in the p97 structure .
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-
-
- HY-174810
-
|
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ADC Linker
|
Cancer
|
|
Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-Cl is a cleavable and silyl ether-based ADC linker that can be used in the synthesis of antibody-drug conjugates (ADC) .
|
-
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- HY-141652
-
|
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Drug Intermediate
|
Cancer
|
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N-2-Azidoethyl betulonamide is the building block, that could generate cytotoxic triazole derivative through click chemistry .
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-
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- HY-173582
-
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2’-Deoxyribavirin-5’-O-triphosphate tetrasodium
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Nucleoside Antimetabolite/Analog
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Others
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1-β-D-2'-Deoxyribofuranosyl-1,2,4-triazole-3-carboxamide-5'-O-triphosphate (tetrasodium) is a nucleotide analog. 1-β-D-2'-Deoxyribofuranosyl-1,2,4-triazole-3-carboxamide-5'-O-triphosphate (tetrasodium) can be used in the investigation of the sequence-saturated mutagenesis (SeSaM) method .
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- HY-W019852R
-
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Reference Standards
Fungal
|
Infection
|
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Flutriafol (Standard) is the analytical standard of Flutriafol. This product is intended for research and analytical applications. Flutriafol is a triazole fungicide with broad spectrum fungicidal activity.
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-
-
- HY-141726S
-
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Isotope-Labeled Compounds
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Others
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rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid-d3 is the deuterium labeled rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid .
|
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- HY-163107
-
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Bacterial
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Infection
|
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Antimycobacterial agent-7 (compound 4) is a 1,2,4-triazole anti-tuberculosis agent (MIC: 2 μg/mL). Antimycobacterial agent-7 inhibits Mtb KatG and causes the accumulation of ROS in Mtb cells. ROS produces oxidative damage, leading to the death of Mtb .
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-
-
- HY-126677
-
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ADC Linker
PROTAC Linkers
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Cancer
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Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double claevable 3-unit and 4-unit PEG linker for antibody-agent-conjugation (ADC). Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA also is a PROTAC linker that can be used in the synthesis of PROTACs.
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-
-
- HY-B0847
-
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Fungal
Reactive Oxygen Species (ROS)
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Infection
|
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Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals .
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-
-
- HY-B2058R
-
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Reference Standards
Fungal
|
Infection
|
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Triticonazole (Standard) is the analytical standard of Triticonazole. This product is intended for research and analytical applications. Triticonazole is a triazole pesticide. Triticonazole is an azole fungicide and shows endocrine disrupting activities .
|
-
-
- HY-B0847R
-
|
|
Reference Standards
Fungal
Reactive Oxygen Species (ROS)
|
Infection
|
|
Propiconazole (Standard) is the analytical standard of Propiconazole. This product is intended for research and analytical applications. Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals .
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-
-
- HY-W727488
-
|
1,2,4-triazole-1-acetic acid-d4
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Isotope-Labeled Compounds
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Others
|
|
2-(1H-1,2,4-Triazol-1-yl)acetic acid-d4 (1,2,4-Triazole-1-acetic acid-d4) is the deuterium labeled 2-(1H-1,2,4-Triazol-1-yl)acetic acid (HY-W028914).
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-
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- HY-14273S
-
|
BAL-4815-d4; RO-0094815-d4
|
Fungal
Cytochrome P450
|
Infection
|
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Isavuconazole-d4 (BAL-4815-d4) is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi .
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-
- HY-76200
-
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UK-109496
|
Fungal
Bacterial
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Infection
Cancer
|
|
Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .
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-
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- HY-76200B
-
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UK-109496 camphorsulfonate
|
Fungal
Bacterial
|
Infection
Cancer
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Voriconazole (UK-109496) camphorsulfonate is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole camphorsulfonate exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .
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-
-
- HY-14273
-
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BAL-4815; RO-0094815
|
Fungal
Cytochrome P450
Antibiotic
|
Infection
Cancer
|
|
Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.
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-
-
- HY-14273R
-
|
BAL-4815 (Standard); RO-0094815 (Standard)
|
Reference Standards
Fungal
Cytochrome P450
Antibiotic
|
Infection
|
|
Isavuconazole (Standard) is the analytical standard of Isavuconazole. This product is intended for research and analytical applications. Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.
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-
- HY-161812
-
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Opioid Receptor
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Others
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MOR agonist-4 (2d) is a G protein signaling-biased Kappa opioid receptor (KOR) agonist with an EC50 value of 11 nM. MOR agonist-4 contains an electron withdrawing CF3 group and a bias factor of 38 based on triazole. MOR agonist-4 is used in the research of pruritis and analgesia .
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- HY-117766
-
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Fungal
Cytochrome P450
|
Infection
|
|
PC945, a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B, with IC50s of 0.23 μM and 0.22 μM, respectively .
|
-
-
- HY-B0101
-
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UK-49858
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Fungal
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
|
-
-
- HY-17514
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Itraconazole
Maximum Cited Publications
21 Publications Verification
R51211
|
Fungal
Hedgehog
Cytochrome P450
Autophagy
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
|
-
-
- HY-B0101R
-
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UK-49858 (Standard)
|
Reference Standards
Fungal
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
|
-
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- HY-17514R
-
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R51211 (Standard)
|
Reference Standards
Fungal
Hedgehog
Cytochrome P450
Autophagy
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Itraconazole (Standard) is the analytical standard of Itraconazole. This product is intended for research and analytical applications. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
|
-
-
- HY-137154
-
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Drug Intermediate
|
Others
|
|
4-Azidobenzenesulfonamide (Compound 12) is a precursor for the synthesis of 1,2,3-triazoles .
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-
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- HY-Y0219S1
-
-
-
- HY-157532
-
-
-
- HY-Y0688S
-
-
-
- HY-Z7147
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate (Efinaconazole Impurity) is a biological molecule.
|
-
-
- HY-17373
-
-
- HY-17373A
-
|
SCH56592 hydrate
|
Fungal
Parasite
|
Infection
Cancer
|
|
Posaconazole hydrate is a broad-spectrum, second generation, triazole compound with antifungal activity.
|
-
- HY-149367
-
|
|
Apoptosis
|
Cancer
|
Anticancer agent 136 (compound 22), a C17-triazole analogue of Geldanamycin (GDM; HY-15230), has an IC50 of 3.38 μM for HDF and a Kd of 3.86 μM for Hsp90. Anticancer agent 136 is an apoptosis-inducing agent .
|
-
- HY-W740506
-
-
- HY-144426
-
|
|
Influenza Virus
|
Infection
|
|
Neuraminidase-IN-6 (Compound 5c) is a potent inhibitor of neuraminidase with an IC50 of 0.11 μM. Neuraminidase-IN-6 is a 1,3,4-triazole-3-acetamide derivative. Neuraminidase (NA) is an ideal target for the development of anti-influenza agents .
|
-
- HY-B0101B
-
-
- HY-B0101A
-
-
- HY-W705791
-
|
|
Fungal
|
Infection
|
|
Metconazole-d6 is the deuterium labeled Metconazole. Metconazole is a triazole fungicide agent.
|
-
- HY-147711
-
|
|
Glycosidase
|
Metabolic Disease
|
|
α-Amylase/α-Glucosidase-IN-1 (compound 33) is a potent α-amylase/α-glucosidase inhibitor with IC50s of 2.01, 2.09 µM for α-amylase and α-glucosidase, respectively. Kinetic studies predict that α-Amylase/α-Glucosidase-IN-1 has the potential of anti hyperglycemia .
|
-
- HY-106141
-
|
UR 9825
|
Fungal
|
Infection
|
|
Albaconazole (UR 9825) is a broad-spectrum triazole and oral activity antifungal agent .
|
-
- HY-B0851
-
|
|
Fungal
|
Infection
|
|
Triadimenol is a triazole fungicide and has been widely used in agriculture. Triadimenol has certain toxicity to animals .
|
-
- HY-Z7147R
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Efinaconazole analogue-1 (Standard) is the analytical standard of Efinaconazole analogue-1. This product is intended for research and analytical applications. 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate (Efinaconazole Impurity) is a biological molecule.
|
-
- HY-121161A
-
|
|
Cytochrome P450
|
Others
|
|
Brassinazole is a selective triazole-type brassinosteroid (BR) biosynthesis inhibitor. Brassinazole is used for regulating plant growth and development .
|
-
- HY-W347315
-
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|
Biochemical Assay Reagents
|
Others
|
|
6-(Biotinamido)hexylazide is a click chemistry biotinylation reagent that can react with alkyne molecule to form a stable triazole linkage.
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-
- HY-117771A
-
|
|
DAGL
|
Metabolic Disease
|
|
DO34 analog is a triazole DAGL(α) inhibitor extracted from patent WO2017096315 A1, compound 100.
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-
- HY-U00249R
-
|
|
Fungal
|
Infection
|
|
Saperconazole (R66905) is a broad-spectrum antifungal triazole and has potent activity against Aspergillus with an MIC90 of 0.19 mg/L.
|
-
- HY-U00249
-
|
R66905
|
Fungal
|
Infection
|
|
Saperconazole (R66905) is a broad-spectrum antifungal triazole and has potent activity against Aspergillus with an MIC90 of 0.19 mg/L.
|
-
- HY-12772
-
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Itraconazole metabolite Hydroxy Itraconazole; R-63373
|
Fungal
Drug Metabolite
|
Others
|
|
Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
|
-
- HY-W700970
-
-
- HY-17373S
-
|
SCH 56592-d5
|
Isotope-Labeled Compounds
Fungal
|
Infection
|
|
Posaconazole-d5 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity .
|
-
- HY-17373S1
-
|
SCH 56592-d4
|
Fungal
|
Infection
|
|
Posaconazole-d4 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity .
|
-
- HY-14272
-
|
BMS-207147; ER-30346
|
Fungal
|
Infection
Cancer
|
|
Ravuconazole (BMS-207147;ER-30346) is an orally available triazole antifungle agent that potently inhibits a wide range of fungi.
|
-
- HY-W749242
-
|
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Fungal
|
Infection
|
|
Paclobutrazol-d4 is the deuterium labeled Paclobutrazol. Paclobutrazol is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins .
|
-
- HY-126475
-
|
|
Bacterial
|
Others
|
|
KSK213 is a 1,2,3-triazole-based Chlamydia infectivity inhibitor with high potency (EC50 ≤ 20 nM) against Chlamydia infectivity.
|
-
- HY-17373R
-
|
SCH 56592 (Standard)
|
Reference Standards
Fungal
Parasite
|
Infection
Cancer
|
|
Posaconazole (Standard) is the analytical standard of Posaconazole. This product is intended for research and analytical applications. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
|
-
- HY-121161
-
|
|
Cytochrome P450
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Metabolic Disease
|
|
(Rac)-Brassinazole, triazole-type compound, is a brassinosteroid (BR) biosynthesis inhibitor. (Rac)-Brassinazole increases inhibition of CYP90B in BR biosynthesis
|
-
- HY-W800689
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Tri(propargyl-NHCO-ethyloxyethyl)amine is a crosslinker that can react with azide compounds or biomolecules via copper catalyzed Click Chemistry to form a stable triazole linkage.
|
-
- HY-145864
-
|
|
VEGFR
|
Cancer
|
|
VEGFR-2-IN-12 (compound 6g), a 2-oxoquinoxalinyl-1,2,4-triazole, is a potent VEGFR-2 inhibitor with an IC50 of 0.037 µM. VEGFR-2-IN-12 shows high growth inhibition against MCF-7 cells (GI50=1.6 µM). VEGFR-2-IN-12 has antitumor activity .
|
-
- HY-130809C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Biotin (MW 3400) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Biotin (MW 40000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-172001
-
|
|
Drug Derivative
|
Cancer
|
|
α-GalCer analog 8 is a triazole derivative of α-Galactosylceramide (HY-102022). α-Galactosylceramide is a synthetic glycolipid with antitumorial and immunostimulatory .
|
-
- HY-130809I
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Biotin (MW 20000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Biotin (MW 5000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Biotin (MW 1000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Biotin (MW 10000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG-Biotin (MW 2000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-158968
-
|
|
MDM-2/p53
|
Cancer
|
|
MMs02943764 is a 1,2,4-triazole derivative with anticancer activity. MMs02943764 has significant antiproliferative effects on multiple cancer cell lines. PAC, a structural analog of MMs02943764, has significant cytotoxicity against the leukemia cell line K562 (IC50=35.264 μM), reduces the degradation of p53 by inhibiting Mdm2 and Pirh2, and induces K562 cell cycle arrest .
|
-
- HY-12772S
-
|
R-63373-d8
|
Fungal
|
Infection
|
|
Hydroxy Itraconazole-d8 is the deuterium labeled Hydroxy Itraconazole (HY-12772). Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
|
-
- HY-17373S3
-
|
SCH 56592-d7
|
Isotope-Labeled Compounds
|
Infection
Cancer
|
|
Posaconazole-d7 (SCH 56592-d7) is deuterium labeled Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
|
-
- HY-B0851S
-
|
|
Fungal
|
Infection
|
|
Triadimenol-d4 is the deuterium labeled Triadimenol . Triadimenol is a triazole fungicide and has been widely used in agriculture. Triadimenol has certain toxicity to animals .
|
-
- HY-17373S2
-
-
- HY-149518
-
|
|
EGFR
Apoptosis
|
Others
|
|
EGFR/BRAFV600E-IN-3 is a EGFR, BRAFV600E and EGFRT790M inhibitor with IC50 value of 57 nM, 68 nM and 9.70 nM. EGFR/BRAFV600E-IN-3 is an apoptotic inducer and also displays promising antioxidant activity .
|
-
- HY-163674
-
|
|
Interleukin Related
|
Inflammation/Immunology
|
|
Mincle agonist 1 (compound 1c) is a Mincle agonist. Mincle agonist 1 can promote IL-1β expression in BMDM cells. Mincle agonist 1 can be used in immune and inflammation related research .
|
-
- HY-148037
-
|
|
Proteasome
|
Cardiovascular Disease
|
|
Thrombin inhibitor 5 (compound 385) is a thrombin inhibitor, with IC50s ranging from 0.1 μM to 1 μM. Thrombin inhibitor 5 can be used for research of venous thromboembolism .
|
-
- HY-175299
-
|
|
Hedgehog
Apoptosis
DNA Methyltransferase
|
Cancer
|
|
Hedgehog IN-11 is an orally active Hedgehog inhibitor. Hedgehog IN-11 downregulates the expression of O6-methylguanine-DNA methyltransferase (MGMT) to impair the Temozolomide (TMZ) (HY-17364) resistance by inhibiting the Hedgehog pathway. Hedgehog IN-11 shows improved inhibition of cell migration and invasion, and induced cell apoptosis in TMZ-resistant GBM cell lines. Hedgehog IN-11 is predicted by computer simulation to have good blood-brain barrier penetration. Hedgehog IN-11 can be used for the study of glioblastoma (GBM) .
|
-
- HY-B0851R
-
|
|
Reference Standards
Fungal
|
Infection
|
|
Triadimenol (Standard) is the analytical standard of Triadimenol. This product is intended for research and analytical applications. Triadimenol is a triazole fungicide and has been widely used in agriculture. Triadimenol has certain toxicity to animals .
|
-
- HY-D2748
-
|
|
Fluorescent Dye
|
Others
|
|
5-JOE azide is a fluorescent dye with the emission in yellow region of the spectrum. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
-
- HY-W800807
-
|
|
Fluorescent Dye
|
Others
|
|
R6G azide, 5-isomer is a xanthene dye with a terminal azide. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
-
- HY-137989A
-
|
Voriconazole oxynitride hydrochloride
|
Drug Metabolite
|
Infection
|
|
Voriconazole N-oxide (Voriconazole oxynitride) (hydrochloride) is the main metabolite of Voriconazole (HY-76200) , a widely used triazole antibiotic (fungal). Voriconazole N-oxide (hydrochloride) provides information on the patient's drug metabolism capacity .
|
-
- HY-W800671
-
|
1,5-Pentane diazide
|
Biochemical Assay Reagents
|
Others
|
|
1,5-Diazidopentane (1,5-Pentane diazide) is a linker with two azide groups which can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
-
- HY-W590544
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-Azidodecane is a compound with an azide head and a 10-carbon tail. The azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D2748
-
|
|
Fluorescent Dyes/Probes
|
|
5-JOE azide is a fluorescent dye with the emission in yellow region of the spectrum. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
-
- HY-W800807
-
|
|
Fluorescent Dyes/Probes
|
|
R6G azide, 5-isomer is a xanthene dye with a terminal azide. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
| Cat. No. |
Product Name |
Type |
-
- HY-Y0219R
-
|
s-triazole (Standard); Pyrrodiazole (Standard)
|
Biochemical Assay Reagents
|
|
1,2,4-Triazole (Standard) is the analytical standard of 1,2,4-Triazole. This product is intended for research and analytical applications. 1,2,4-Triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-Y0219
-
|
s-triazole; Pyrrodiazole
|
Biochemical Assay Reagents
|
|
1,2,4-Triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-107870
-
|
|
Chelators
|
|
1,2,4-Triazole-3-carboxylic acid, 97% is a biochemical assay reagent.
|
-
- HY-W012991
-
|
|
Biochemical Assay Reagents
|
|
1,2-Dihydro-3H-1,2,4-triazole-3-thione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007685
-
|
|
Biochemical Assay Reagents
|
|
Methyl 1H-1,2,4-triazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-163789
-
|
|
Biochemical Assay Reagents
|
|
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-W700970
-
|
|
Carbohydrates
|
|
1,4-Phenylenebismaleimide is a biochemical assay reagent.
|
-
- HY-130809C
-
|
|
Drug Delivery
|
|
DBCO-PEG-Biotin (MW 3400) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809H
-
|
|
Drug Delivery
|
|
DBCO-PEG-Biotin (MW 40000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809I
-
|
|
Drug Delivery
|
|
DBCO-PEG-Biotin (MW 20000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809D
-
|
|
Drug Delivery
|
|
DBCO-PEG-Biotin (MW 5000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809A
-
|
|
Drug Delivery
|
|
DBCO-PEG-Biotin (MW 1000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809E
-
|
|
Drug Delivery
|
|
DBCO-PEG-Biotin (MW 10000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809B
-
|
|
Drug Delivery
|
|
DBCO-PEG-Biotin (MW 2000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-76200
-
|
UK-109496
|
Microorganisms
Source classification
|
Fungal
Bacterial
|
|
Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .
|
-
-
- HY-B0101
-
|
UK-49858
|
Microorganisms
Source classification
|
Fungal
Antibiotic
Bacterial
|
|
Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
|
-
-
- HY-17514
-
Itraconazole
Maximum Cited Publications
21 Publications Verification
R51211
|
Microorganisms
Source classification
|
Fungal
Hedgehog
Cytochrome P450
Autophagy
Antibiotic
Bacterial
|
|
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
|
-
-
- HY-B0101R
-
|
UK-49858 (Standard)
|
Microorganisms
Source classification
|
Reference Standards
Fungal
Antibiotic
Bacterial
|
|
Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
|
-
-
- HY-17514R
-
|
R51211 (Standard)
|
Microorganisms
Source classification
|
Reference Standards
Fungal
Hedgehog
Cytochrome P450
Autophagy
Antibiotic
Bacterial
|
|
Itraconazole (Standard) is the analytical standard of Itraconazole. This product is intended for research and analytical applications. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-14273S
-
|
|
|
Isavuconazole-d4 (BAL-4815-d4) is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi .
|
-
-
- HY-Y0219S1
-
|
|
|
NSC 83128-d3 is the deuterium labeled NSC 83128 .
|
-
-
- HY-Y0688S
-
|
|
|
1H-Benzotriazole-4,5,6,7-d4 is the deuterium labeled 1H-Benzo[d][1,2,3]triazole .
|
-
-
- HY-17373S
-
|
|
|
Posaconazole-d5 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity .
|
-
-
- HY-141941S
-
|
|
|
Triazole Lactic Acid- 13C2, 15N3 is the 13C and 15N labeled Triazole Lactic Acid .
|
-
-
- HY-W098127S
-
|
|
|
Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate-d2 is the deuterium labeled Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate .
|
-
-
- HY-141726S
-
|
|
|
rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid-d3 is the deuterium labeled rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid .
|
-
-
- HY-W727488
-
|
|
|
2-(1H-1,2,4-Triazol-1-yl)acetic acid-d4 (1,2,4-Triazole-1-acetic acid-d4) is the deuterium labeled 2-(1H-1,2,4-Triazol-1-yl)acetic acid (HY-W028914).
|
-
-
- HY-W740506
-
|
|
|
1-(2-Pyridinyl)benzotriazole- 15N3 is the 15N labeled 1-(Pyridin-2-yl)-1H-benzo[d][1,2,3]triazole (HY-W275883).
|
-
-
- HY-W705791
-
|
|
|
Metconazole-d6 is the deuterium labeled Metconazole. Metconazole is a triazole fungicide agent.
|
-
-
- HY-17373S1
-
|
|
|
Posaconazole-d4 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity .
|
-
-
- HY-W749242
-
|
|
|
Paclobutrazol-d4 is the deuterium labeled Paclobutrazol. Paclobutrazol is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins .
|
-
-
- HY-12772S
-
|
|
|
Hydroxy Itraconazole-d8 is the deuterium labeled Hydroxy Itraconazole (HY-12772). Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
|
-
-
- HY-17373S3
-
|
|
|
Posaconazole-d7 (SCH 56592-d7) is deuterium labeled Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
|
-
-
- HY-B0851S
-
|
|
|
Triadimenol-d4 is the deuterium labeled Triadimenol . Triadimenol is a triazole fungicide and has been widely used in agriculture. Triadimenol has certain toxicity to animals .
|
-
-
- HY-17373S2
-
|
|
|
Posaconazole-d3 (SCH 56592-d3) is deuterium labeled Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-163789
-
|
|
|
DBCO
|
|
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-141652
-
|
|
|
Azide
|
|
N-2-Azidoethyl betulonamide is the building block, that could generate cytotoxic triazole derivative through click chemistry .
|
-
- HY-130809C
-
|
|
|
DBCO
|
|
DBCO-PEG-Biotin (MW 3400) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809H
-
|
|
|
DBCO
|
|
DBCO-PEG-Biotin (MW 40000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809I
-
|
|
|
DBCO
|
|
DBCO-PEG-Biotin (MW 20000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809D
-
|
|
|
DBCO
|
|
DBCO-PEG-Biotin (MW 5000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809A
-
|
|
|
DBCO
|
|
DBCO-PEG-Biotin (MW 1000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809E
-
|
|
|
DBCO
|
|
DBCO-PEG-Biotin (MW 10000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809B
-
|
|
|
DBCO
|
|
DBCO-PEG-Biotin (MW 2000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-D2748
-
|
|
|
Azide
|
|
5-JOE azide is a fluorescent dye with the emission in yellow region of the spectrum. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
| Cat. No. |
Product Name |
|
Classification |
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