Search Result
Results for "
2-Ar-1,2,3-triazole
" in MedChemExpress (MCE) Product Catalog:
14
Biochemical Assay Reagents
16
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-Y0219R
-
s-triazole (Standard); Pyrrodiazole (Standard)
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Biochemical Assay Reagents
Reference Standards
|
Others
|
1,2,4-Triazole (Standard) is the analytical standard of 1,2,4-Triazole. This product is intended for research and analytical applications. 1,2,4-Triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-Y0219
-
s-triazole; Pyrrodiazole
|
Biochemical Assay Reagents
|
Others
|
1,2,4-Triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-Y0219A
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s-triazole sodium; Pyrrodiazole sodium
|
Biochemical Assay Reagents
|
Infection
|
1,2,4-Triazole (sodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
-
- HY-W113615
-
-
-
- HY-107870
-
-
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- HY-W012991
-
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Biochemical Assay Reagents
|
Others
|
1,2-Dihydro-3H-1,2,4-triazole-3-thione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-W007685
-
|
Biochemical Assay Reagents
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Others
|
Methyl 1H-1,2,4-triazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
-
- HY-141941S
-
-
-
- HY-169368
-
-
-
- HY-174304
-
|
Drug-Linker Conjugates for ADC
|
Cancer
|
Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide is a drug-linker conjugate for ADC. Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide consists of a Triptolide (HY-32735) and a stable and cleavable linker (Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-Cl) (HY-174810). Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide can be used for synthesis of antibody-drug conjugates (ADC) .
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-
-
- HY-W331786
-
|
Bacterial
|
Infection
|
Ipconazole is a triazole fungicide that can be used for treating rice seed .
|
-
-
- HY-163789
-
|
ADC Linker
|
Cancer
|
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
-
- HY-WAA0156
-
|
Drug Intermediate
|
Others
|
1-(Pyrrolidin-3-yl)-1H-1,2,4-triazole oxalate is a drug intermediate for synthesis of various active compounds.
|
-
-
- HY-W586475
-
|
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
Fluorescein-triazole-PEG5-DOTA is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
|
-
-
- HY-46369
-
|
DNA/RNA Synthesis
|
Others
|
1-p-Chlorobenzyl-1,2,3-triazole-5′-O-DMT-dU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
-
- HY-W098127S
-
|
Isotope-Labeled Compounds
|
Others
|
Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate-d2 is the deuterium labeled Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate .
|
-
-
- HY-W331786R
-
|
Reference Standards
Bacterial
|
Infection
|
Ipconazole (Standard) is the analytical standard of Ipconazole. This product is intended for research and analytical applications. Ipconazole is a triazole fungicide that can be used for treating rice seed .
|
-
-
- HY-168006
-
|
p97
ATP Synthase
|
Cancer
|
NSC819701 is a triazole inhibitor of the p97 ATPase. NSC819701 inhibits the activity of p97 ATPase by binding to a specific site of p97 .
|
-
-
- HY-W019852
-
|
Fungal
|
Infection
|
Flutriafol is a triazole fungicide with broad spectrum fungicidal activity.
|
-
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- HY-B2058
-
|
Fungal
|
Infection
|
Triticonazole is a triazole pesticide. Triticonazole is an azole fungicide and shows endocrine disrupting activities .
|
-
-
- HY-168005
-
|
p97
ATP Synthase
|
Cancer
|
NSC799462 is a triazole inhibitor of p97 ATPase. NSC799462 inhibits p97 ATPase activity (IC50 = 15 nM) by binding to a specific site on p97 and causing local changes in the p97 structure .
|
-
-
- HY-174810
-
|
ADC Linker
|
Cancer
|
Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-Cl is a cleavable and silyl ether-based ADC linker that can be used in the synthesis of antibody-drug conjugates (ADC) .
|
-
-
- HY-173582
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2’-Deoxyribavirin-5’-O-triphosphate tetrasodium
|
Nucleoside Antimetabolite/Analog
|
Others
|
1-β-D-2'-Deoxyribofuranosyl-1,2,4-triazole-3-carboxamide-5'-O-triphosphate (tetrasodium) is a nucleotide analog. 1-β-D-2'-Deoxyribofuranosyl-1,2,4-triazole-3-carboxamide-5'-O-triphosphate (tetrasodium) can be used in the investigation of the sequence-saturated mutagenesis (SeSaM) method .
|
-
-
- HY-141652
-
|
Drug Intermediate
|
Cancer
|
N-2-Azidoethyl betulonamide is the building block, that could generate cytotoxic triazole derivative through click chemistry .
|
-
-
- HY-W019852R
-
|
Reference Standards
Fungal
|
Infection
|
Flutriafol (Standard) is the analytical standard of Flutriafol. This product is intended for research and analytical applications. Flutriafol is a triazole fungicide with broad spectrum fungicidal activity.
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-
-
- HY-141726S
-
|
Isotope-Labeled Compounds
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Others
|
rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid-d3 is the deuterium labeled rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid .
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-
- HY-126677
-
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ADC Linker
PROTAC Linkers
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Cancer
|
Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double claevable 3-unit and 4-unit PEG linker for antibody-agent-conjugation (ADC). Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA also is a PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-163107
-
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Bacterial
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Infection
|
Antimycobacterial agent-7 (compound 4) is a 1,2,4-triazole anti-tuberculosis agent (MIC: 2 μg/mL). Antimycobacterial agent-7 inhibits Mtb KatG and causes the accumulation of ROS in Mtb cells. ROS produces oxidative damage, leading to the death of Mtb .
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-
-
- HY-B2058R
-
|
Reference Standards
Fungal
|
Infection
|
Triticonazole (Standard) is the analytical standard of Triticonazole. This product is intended for research and analytical applications. Triticonazole is a triazole pesticide. Triticonazole is an azole fungicide and shows endocrine disrupting activities .
|
-
-
- HY-B0847
-
|
Fungal
Reactive Oxygen Species (ROS)
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Infection
|
Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals .
|
-
-
- HY-B0847R
-
|
Reference Standards
Fungal
Reactive Oxygen Species (ROS)
|
Infection
|
Propiconazole (Standard) is the analytical standard of Propiconazole. This product is intended for research and analytical applications. Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals .
|
-
-
- HY-14273S
-
BAL-4815-d4; RO-0094815-d4
|
Fungal
Cytochrome P450
|
Infection
|
Isavuconazole-d4 is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi .
|
-
-
- HY-W727488
-
1,2,4-triazole-1-acetic acid-d4
|
Isotope-Labeled Compounds
|
Others
|
2-(1H-1,2,4-Triazol-1-yl)acetic acid-d4 (1,2,4-Triazole-1-acetic acid-d4) is the deuterium labeled 2-(1H-1,2,4-Triazol-1-yl)acetic acid (HY-W028914).
|
-
-
- HY-76200
-
UK-109496
|
Fungal
Bacterial
|
Infection
Cancer
|
Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .
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- HY-76200B
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UK-109496 camphorsulfonate
|
Fungal
Bacterial
|
Infection
Cancer
|
Voriconazole (UK-109496) camphorsulfonate is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole camphorsulfonate exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .
|
-
-
- HY-14273
-
BAL-4815; RO-0094815
|
Fungal
Cytochrome P450
Antibiotic
|
Infection
Cancer
|
Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.
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-
-
- HY-14273R
-
BAL-4815 (Standard); RO-0094815 (Standard)
|
Reference Standards
Fungal
Cytochrome P450
Antibiotic
|
Infection
|
Isavuconazole (Standard) is the analytical standard of Isavuconazole. This product is intended for research and analytical applications. Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.
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-
-
- HY-161812
-
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Opioid Receptor
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Others
|
MOR agonist-4 (2d) is a G protein signaling-biased Kappa opioid receptor (KOR) agonist with an EC50 value of 11 nM. MOR agonist-4 contains an electron withdrawing CF3 group and a bias factor of 38 based on triazole. MOR agonist-4 is used in the research of pruritis and analgesia .
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-
-
- HY-117766
-
|
Fungal
Cytochrome P450
|
Infection
|
PC945, a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B, with IC50s of 0.23 μM and 0.22 μM, respectively .
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-
-
- HY-B0101
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UK-49858
|
Fungal
Antibiotic
Bacterial
|
Infection
Cancer
|
Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
|
-
-
- HY-17514
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Itraconazole
Maximum Cited Publications
19 Publications Verification
R51211
|
Fungal
Hedgehog
Cytochrome P450
Autophagy
Antibiotic
Bacterial
|
Infection
Cancer
|
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
|
-
-
- HY-B0101R
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UK-49858 (Standard)
|
Reference Standards
Fungal
Antibiotic
Bacterial
|
Infection
Cancer
|
Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
|
-
-
- HY-17514R
-
R51211 (Standard)
|
Reference Standards
Fungal
Hedgehog
Cytochrome P450
Autophagy
Antibiotic
Bacterial
|
Infection
Cancer
|
Itraconazole (Standard) is the analytical standard of Itraconazole. This product is intended for research and analytical applications. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
|
-
-
- HY-137154
-
|
Drug Intermediate
|
Others
|
4-Azidobenzenesulfonamide (Compound 12) is a precursor for the synthesis of 1,2,3-triazoles .
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-
-
- HY-Y0219S1
-
-
-
- HY-157532
-
-
-
- HY-Y0688S
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-
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- HY-Z7147
-
|
Biochemical Assay Reagents
|
Others
|
1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate (Efinaconazole Impurity) is a biological molecule.
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-
-
- HY-17373
-
-
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- HY-17373A
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SCH56592 hydrate
|
Fungal
Parasite
|
Infection
Cancer
|
Posaconazole hydrate is a broad-spectrum, second generation, triazole compound with antifungal activity.
|
-
- HY-149367
-
|
Apoptosis
|
Cancer
|
Anticancer agent 136 (compound 22), a C17-triazole analogue of Geldanamycin (GDM; HY-15230), has an IC50 of 3.38 μM for HDF and a Kd of 3.86 μM for Hsp90. Anticancer agent 136 is an apoptosis-inducing agent .
|
-
- HY-W740506
-
-
- HY-144426
-
|
Influenza Virus
|
Infection
|
Neuraminidase-IN-6 (Compound 5c) is a potent inhibitor of neuraminidase with an IC50 of 0.11 μM. Neuraminidase-IN-6 is a 1,3,4-triazole-3-acetamide derivative. Neuraminidase (NA) is an ideal target for the development of anti-influenza agents .
|
-
- HY-W705791
-
|
Fungal
|
Infection
|
Metconazole-d6 is the deuterium labeled Metconazole. Metconazole is a triazole fungicide agent.
|
-
- HY-B0101B
-
-
- HY-B0101A
-
-
- HY-147711
-
|
Glycosidase
|
Metabolic Disease
|
α-Amylase/α-Glucosidase-IN-1 (compound 33) is a potent α-amylase/α-glucosidase inhibitor with IC50s of 2.01, 2.09 µM for α-amylase and α-glucosidase, respectively. Kinetic studies predict that α-Amylase/α-Glucosidase-IN-1 has the potential of anti hyperglycemia .
|
-
- HY-106141
-
UR 9825
|
Fungal
|
Infection
|
Albaconazole (UR 9825) is a broad-spectrum triazole and oral activity antifungal agent .
|
-
- HY-B0851
-
|
Fungal
|
Infection
|
Triadimenol is a triazole fungicide and has been widely used in agriculture. Triadimenol has certain toxicity to animals .
|
-
- HY-121161A
-
|
Cytochrome P450
|
Others
|
Brassinazole is a selective triazole-type brassinosteroid (BR) biosynthesis inhibitor. Brassinazole is used for regulating plant growth and development .
|
-
- HY-117771A
-
|
DAGL
|
Metabolic Disease
|
DO34 analog is a triazole DAGL(α) inhibitor extracted from patent WO2017096315 A1, compound 100.
|
-
- HY-W347315
-
|
Biochemical Assay Reagents
|
Others
|
6-(Biotinamido)hexylazide is a click chemistry biotinylation reagent that can react with alkyne molecule to form a stable triazole linkage.
|
-
- HY-U00249
-
R66905
|
Fungal
|
Infection
|
Saperconazole (R66905) is a broad-spectrum antifungal triazole and has potent activity against Aspergillus with an MIC90 of 0.19 mg/L.
|
-
- HY-12772
-
Itraconazole metabolite Hydroxy Itraconazole; R-63373
|
Fungal
Drug Metabolite
|
Others
|
Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
|
-
- HY-W700970
-
-
- HY-126475
-
|
Bacterial
|
Others
|
KSK213 is a 1,2,3-triazole-based Chlamydia infectivity inhibitor with high potency (EC50 ≤ 20 nM) against Chlamydia infectivity.
|
-
- HY-17373S
-
SCH 56592-d5
|
Isotope-Labeled Compounds
Fungal
|
Infection
|
Posaconazole-d5 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity .
|
-
- HY-17373S1
-
SCH 56592-d4
|
Fungal
|
Infection
|
Posaconazole-d4 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity .
|
-
- HY-14272
-
BMS-207147; ER-30346
|
Fungal
|
Infection
Cancer
|
Ravuconazole (BMS-207147;ER-30346) is an orally available triazole antifungle agent that potently inhibits a wide range of fungi.
|
-
- HY-W749242
-
|
Fungal
|
Infection
|
Paclobutrazol-d4 is the deuterium labeled Paclobutrazol. Paclobutrazol is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins .
|
-
- HY-17373R
-
SCH 56592 (Standard)
|
Reference Standards
Fungal
Parasite
|
Infection
Cancer
|
Posaconazole (Standard) is the analytical standard of Posaconazole. This product is intended for research and analytical applications. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
|
-
- HY-12772S
-
R-63373-d8
|
Fungal
|
Others
|
Hydroxy Itraconazole-d8 is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
|
-
- HY-121161
-
|
Cytochrome P450
|
Metabolic Disease
|
(Rac)-Brassinazole, triazole-type compound, is a brassinosteroid (BR) biosynthesis inhibitor. (Rac)-Brassinazole increases inhibition of CYP90B in BR biosynthesis
|
-
- HY-W800689
-
|
Biochemical Assay Reagents
|
Others
|
Tri(propargyl-NHCO-ethyloxyethyl)amine is a crosslinker that can react with azide compounds or biomolecules via copper catalyzed Click Chemistry to form a stable triazole linkage.
|
-
- HY-145864
-
|
VEGFR
|
Cancer
|
VEGFR-2-IN-12 (compound 6g), a 2-oxoquinoxalinyl-1,2,4-triazole, is a potent VEGFR-2 inhibitor with an IC50 of 0.037 µM. VEGFR-2-IN-12 shows high growth inhibition against MCF-7 cells (GI50=1.6 µM). VEGFR-2-IN-12 has antitumor activity .
|
-
- HY-130809C
-
|
Biochemical Assay Reagents
|
Others
|
DBCO-PEG-Biotin (MW 3400) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809H
-
|
Biochemical Assay Reagents
|
Others
|
DBCO-PEG-Biotin (MW 40000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-172001
-
|
Drug Derivative
|
Cancer
|
α-GalCer analog 8 is a triazole derivative of α-Galactosylceramide (HY-102022). α-Galactosylceramide is a synthetic glycolipid with antitumorial and immunostimulatory .
|
-
- HY-130809I
-
|
Biochemical Assay Reagents
|
Others
|
DBCO-PEG-Biotin (MW 20000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809D
-
|
Biochemical Assay Reagents
|
Others
|
DBCO-PEG-Biotin (MW 5000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809A
-
|
Biochemical Assay Reagents
|
Others
|
DBCO-PEG-Biotin (MW 1000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809E
-
|
Biochemical Assay Reagents
|
Others
|
DBCO-PEG-Biotin (MW 10000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809B
-
|
Biochemical Assay Reagents
|
Others
|
DBCO-PEG-Biotin (MW 2000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-158968
-
|
MDM-2/p53
|
Cancer
|
MMs02943764 is a 1,2,4-triazole derivative with anticancer activity. MMs02943764 has significant antiproliferative effects on multiple cancer cell lines. PAC, a structural analog of MMs02943764, has significant cytotoxicity against the leukemia cell line K562 (IC50=35.264 μM), reduces the degradation of p53 by inhibiting Mdm2 and Pirh2, and induces K562 cell cycle arrest .
|
-
- HY-17373S3
-
SCH 56592-d7
|
Isotope-Labeled Compounds
|
Infection
Cancer
|
Posaconazole-d7 (SCH 56592-d7) is deuterium labeled Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
|
-
- HY-B0851S
-
|
Fungal
|
Infection
|
Triadimenol-d4 is the deuterium labeled Triadimenol . Triadimenol is a triazole fungicide and has been widely used in agriculture. Triadimenol has certain toxicity to animals .
|
-
- HY-17373S2
-
-
- HY-163674
-
|
Interleukin Related
|
Inflammation/Immunology
|
Mincle agonist 1 (compound 1c) is a Mincle agonist. Mincle agonist 1 can promote IL-1β expression in BMDM cells. Mincle agonist 1 can be used in immune and inflammation related research .
|
-
- HY-149518
-
|
EGFR
Apoptosis
|
Others
|
EGFR/BRAFV600E-IN-3 is a EGFR, BRAFV600E and EGFRT790M inhibitor with IC50 value of 57 nM, 68 nM and 9.70 nM. EGFR/BRAFV600E-IN-3 is an apoptotic inducer and also displays promising antioxidant activity .
|
-
- HY-148037
-
|
Proteasome
|
Cardiovascular Disease
|
Thrombin inhibitor 5 (compound 385) is a thrombin inhibitor, with IC50s ranging from 0.1 μM to 1 μM. Thrombin inhibitor 5 can be used for research of venous thromboembolism .
|
-
- HY-B0851R
-
|
Reference Standards
Fungal
|
Infection
|
Triadimenol (Standard) is the analytical standard of Triadimenol. This product is intended for research and analytical applications. Triadimenol is a triazole fungicide and has been widely used in agriculture. Triadimenol has certain toxicity to animals .
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-
- HY-D2748
-
|
Fluorescent Dye
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Others
|
5-JOE azide is a fluorescent dye with the emission in yellow region of the spectrum. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
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-
- HY-W800807
-
|
Fluorescent Dye
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Others
|
R6G azide, 5-isomer is a xanthene dye with a terminal azide. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
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-
- HY-137989A
-
Voriconazole oxynitride hydrochloride
|
Drug Metabolite
|
Infection
|
Voriconazole N-oxide (Voriconazole oxynitride) (hydrochloride) is the main metabolite of Voriconazole (HY-76200) , a widely used triazole antibiotic (fungal). Voriconazole N-oxide (hydrochloride) provides information on the patient's drug metabolism capacity .
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-
- HY-W800671
-
1,5-Pentane diazide
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Biochemical Assay Reagents
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Others
|
1,5-Diazidopentane (1,5-Pentane diazide) is a linker with two azide groups which can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
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-
- HY-W590544
-
|
Biochemical Assay Reagents
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Others
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1-Azidodecane is a compound with an azide head and a 10-carbon tail. The azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
-
- HY-135761
-
|
Fungal
Cholinesterase (ChE)
|
Infection
Neurological Disease
|
Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats .
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-
- HY-W590592
-
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Biochemical Assay Reagents
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Others
|
Azido-PEG12-azide is a monodisperse PEG linker containing two azide groups. The azide group can react with alkyne, BCN, or DBCO via Click Chemistry to yield a stable triazole linkage.
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-
- HY-119683A
-
|
Fungal
Apoptosis
|
Infection
|
(Rac)-Epoxiconazole is a chiral triazole fungicide that is released into the environment as a racemate and has broad-spectrum, long-acting, and excellent fungicidal effects. (Rac)-Epoxiconazole is highly persistent in soil, with a reported half-life of more than 300 days .
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-
- HY-14272R
-
BMS-207147 (Standard); ER-30346 (Standard)
|
Reference Standards
Fungal
|
Infection
Cancer
|
Ravuconazole (Standard) is the analytical standard of Ravuconazole. This product is intended for research and analytical applications. Ravuconazole (BMS-207147;ER-30346) is an orally available triazole antifungle agent that potently inhibits a wide range of fungi.
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-
Cat. No. |
Product Name |
Type |
-
- HY-D2748
-
|
Fluorescent Dyes/Probes
|
5-JOE azide is a fluorescent dye with the emission in yellow region of the spectrum. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
-
- HY-W800807
-
|
Fluorescent Dyes/Probes
|
R6G azide, 5-isomer is a xanthene dye with a terminal azide. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
Cat. No. |
Product Name |
Type |
-
- HY-Y0219R
-
s-triazole (Standard); Pyrrodiazole (Standard)
|
Biochemical Assay Reagents
|
1,2,4-Triazole (Standard) is the analytical standard of 1,2,4-Triazole. This product is intended for research and analytical applications. 1,2,4-Triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-Y0219
-
s-triazole; Pyrrodiazole
|
Biochemical Assay Reagents
|
1,2,4-Triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-107870
-
|
Chelators
|
1,2,4-Triazole-3-carboxylic acid, 97% is a biochemical assay reagent.
|
-
- HY-W012991
-
|
Biochemical Assay Reagents
|
1,2-Dihydro-3H-1,2,4-triazole-3-thione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007685
-
|
Biochemical Assay Reagents
|
Methyl 1H-1,2,4-triazole-3-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-163789
-
|
Biochemical Assay Reagents
|
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-W700970
-
|
Carbohydrates
|
1,4-Phenylenebismaleimide is a biochemical assay reagent.
|
-
- HY-130809C
-
|
Drug Delivery
|
DBCO-PEG-Biotin (MW 3400) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809H
-
|
Drug Delivery
|
DBCO-PEG-Biotin (MW 40000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809I
-
|
Drug Delivery
|
DBCO-PEG-Biotin (MW 20000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809D
-
|
Drug Delivery
|
DBCO-PEG-Biotin (MW 5000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809A
-
|
Drug Delivery
|
DBCO-PEG-Biotin (MW 1000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809E
-
|
Drug Delivery
|
DBCO-PEG-Biotin (MW 10000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
-
- HY-130809B
-
|
Drug Delivery
|
DBCO-PEG-Biotin (MW 2000) is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-76200
-
UK-109496
|
Microorganisms
Source classification
|
Fungal
Bacterial
|
Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .
|
-
-
- HY-B0101
-
UK-49858
|
Microorganisms
Source classification
|
Fungal
Antibiotic
Bacterial
|
Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
|
-
-
- HY-17514
-
Itraconazole
Maximum Cited Publications
19 Publications Verification
R51211
|
Microorganisms
Source classification
|
Fungal
Hedgehog
Cytochrome P450
Autophagy
Antibiotic
Bacterial
|
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
|
-
-
- HY-B0101R
-
UK-49858 (Standard)
|
Microorganisms
Source classification
|
Reference Standards
Fungal
Antibiotic
Bacterial
|
Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
|
-
-
- HY-17514R
-
R51211 (Standard)
|
Microorganisms
Source classification
|
Reference Standards
Fungal
Hedgehog
Cytochrome P450
Autophagy
Antibiotic
Bacterial
|
Itraconazole (Standard) is the analytical standard of Itraconazole. This product is intended for research and analytical applications. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
|
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-14273S
-
|
Isavuconazole-d4 is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi .
|
-
-
- HY-Y0688S
-
|
1H-Benzotriazole-4,5,6,7-d4 is the deuterium labeled 1H-Benzo[d][1,2,3]triazole .
|
-
-
- HY-17373S
-
|
Posaconazole-d5 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity .
|
-
-
- HY-141941S
-
|
Triazole Lactic Acid- 13C2, 15N3 is the 13C and 15N labeled Triazole Lactic Acid .
|
-
-
- HY-W098127S
-
|
Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate-d2 is the deuterium labeled Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate .
|
-
-
- HY-141726S
-
|
rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid-d3 is the deuterium labeled rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid .
|
-
-
- HY-W727488
-
|
2-(1H-1,2,4-Triazol-1-yl)acetic acid-d4 (1,2,4-Triazole-1-acetic acid-d4) is the deuterium labeled 2-(1H-1,2,4-Triazol-1-yl)acetic acid (HY-W028914).
|
-
-
- HY-Y0219S1
-
|
NSC 83128-d3 is the deuterium labeled NSC 83128 .
|
-
-
- HY-W740506
-
|
1-(2-Pyridinyl)benzotriazole- 15N3 is the 15N labeled 1-(Pyridin-2-yl)-1H-benzo[d][1,2,3]triazole (HY-W275883).
|
-
-
- HY-W705791
-
|
Metconazole-d6 is the deuterium labeled Metconazole. Metconazole is a triazole fungicide agent.
|
-
-
- HY-17373S1
-
|
Posaconazole-d4 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity .
|
-
-
- HY-W749242
-
|
Paclobutrazol-d4 is the deuterium labeled Paclobutrazol. Paclobutrazol is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins .
|
-
-
- HY-12772S
-
|
Hydroxy Itraconazole-d8 is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
|
-
-
- HY-17373S3
-
|
Posaconazole-d7 (SCH 56592-d7) is deuterium labeled Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
|
-
-
- HY-B0851S
-
|
Triadimenol-d4 is the deuterium labeled Triadimenol . Triadimenol is a triazole fungicide and has been widely used in agriculture. Triadimenol has certain toxicity to animals .
|
-
-
- HY-17373S2
-
|
Posaconazole-d3 (SCH 56592-d3) is deuterium labeled Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
|
-
Cat. No. |
Product Name |
|
Classification |
-
- HY-141652
-
|
|
Azide
|
N-2-Azidoethyl betulonamide is the building block, that could generate cytotoxic triazole derivative through click chemistry .
|
-
- HY-D2748
-
|
|
Azide
|
5-JOE azide is a fluorescent dye with the emission in yellow region of the spectrum. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
Cat. No. |
Product Name |
|
Classification |
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