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Results for "

2,2'-isomer)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Isomer (17) 5-HT Receptor (1) ADC Payload (2) AMPK (1) Apoptosis (3) Autophagy (3) Bcl-2 Family (4) Biochemical Assay Reagents (7) Cannabinoid Receptor (4) CaSR (1) CDK (1) Dipeptidyl Peptidase (1) Dopamine Receptor (1) Drug Intermediate (1) Endogenous Metabolite (4) Fatty Acid Synthase (FASN) (1) Free Fatty Acid Receptor (1) Histone Demethylase (1) Histone Methyltransferase (1) Isocitrate Dehydrogenase (IDH) (1) Isotope-Labeled Compounds (1) MARK (1) MetAP (1) mGluR (1) MMP (3) Monoamine Oxidase (1) Myosin (1) Na+/H+ Exchanger (NHE) (1) Neurokinin Receptor (2) Phosphodiesterase (PDE) (1) PROTACs (2) Protein Arginine Deiminase (2) Ras (1) Reference Standards (1) Salt-inducible Kinase (SIK) (1) SARS-CoV (1) Src (1) Tie (1) Topoisomerase (2) TRP Channel (1) VEGFR (1)
By Research Areas:	Cancer (20) Cardiovascular Disease (3) Endocrinology (1) Infection (1) Inflammation/Immunology (2) Metabolic Disease (7) Neurological Disease (26)

By Targets:

Drug Isomer (17)

5-HT Receptor (1)

ADC Payload (2)

AMPK (1)

Apoptosis (3)

Autophagy (3)

Bcl-2 Family (4)

Biochemical Assay Reagents (7)

Cannabinoid Receptor (4)

CaSR (1)

CDK (1)

Dipeptidyl Peptidase (1)

Dopamine Receptor (1)

Drug Intermediate (1)

Endogenous Metabolite (4)

Fatty Acid Synthase (FASN) (1)

Free Fatty Acid Receptor (1)

Histone Demethylase (1)

Histone Methyltransferase (1)

Isocitrate Dehydrogenase (IDH) (1)

Isotope-Labeled Compounds (1)

MARK (1)

MetAP (1)

mGluR (1)

MMP (3)

Monoamine Oxidase (1)

Myosin (1)

Na+/H+ Exchanger (NHE) (1)

Neurokinin Receptor (2)

Phosphodiesterase (PDE) (1)

PROTACs (2)

Protein Arginine Deiminase (2)

Ras (1)

Reference Standards (1)

Salt-inducible Kinase (SIK) (1)

SARS-CoV (1)

Src (1)

Tie (1)

Topoisomerase (2)

TRP Channel (1)

VEGFR (1)

By Research Areas:

Cancer (20)

Cardiovascular Disease (3)

Endocrinology (1)

Infection (1)

Inflammation/Immunology (2)

Metabolic Disease (7)

Neurological Disease (26)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Drug Isomer CD22 URAT1 Oct3/4

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-172041

PB-22 6-Hydroxyquinoline isomer	Drug Isomer	Neurological Disease
PB-22 6-Hydroxyquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172042

PB-22 7-Hydroxyquinoline isomer	Drug Isomer	Neurological Disease
PB-22 7-Hydroxyquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172053

PB-22 8-Hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
PB-22 8-Hydroxyisoquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172040

PB-22 5-Hydroxyquinoline isomer	Drug Isomer	Neurological Disease
PB-22 5-hydroxyquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172051

PB-22 6-Hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
PB-22 6-Hydroxyisoquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172050

PB-22 5-Hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
PB-22 5-Hydroxyisoquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172052

PB-22 7-Hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
PB-22 7-Hydroxyisoquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172048

5-Fluoro PB-22 6-hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 6-hydroxyisoquinoline isomer is a structural isomer of 5-Fluoro PB-22.

HY-172047

5-Fluoro PB-22 5-hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 5-hydroxyisoquinoline isomer is a structural isomer of 5-Fluoro PB-22.

HY-172049

5-Fluoro PB-22 7-hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 7-hydroxyisoquinoline isomer is a structural isomer of 5-Fluoro PB-22.

HY-172036

5-Fluoro PB-22 6-hydroxyquinoline isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 N-(3-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22.

HY-172044

5-Fluoro PB-22 N-(3-fluoropentyl) isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 N-(3-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22.

HY-172045

5-Fluoro PB-22 N-(4-fluoropentyl) isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 N-(4-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22.

HY-172037

5-Fluoro PB-22 7-hydroxyquinoline isomer	Cannabinoid Receptor	Neurological Disease
5-Fluoro PB-22 7-hydroxyquinoline isomer is a synthetic cannabinoid.

HY-172035

5-Fluoro PB-22 5-hydroxyquinoline isomer	Cannabinoid Receptor	Neurological Disease
5-Fluoro PB-22 5-hydroxyquinoline isomer is a synthetic cannabinoid.

HY-W768607

5-Fluoro PB-22 8-hydroxyisoquinoline isomer	Cannabinoid Receptor	Neurological Disease
5-Fluoro PB-22 8-hydroxyisoquinoline isomer is structurally similar to known synthetic cannabinoids.

HY-N15816

*18:1 BMP (R,R'; 2,2'-isomer) ammonium*	Biochemical Assay Reagents	Others
18:1 BMP (R,R'; 2,2'-isomer) ammonium is a bis(monoacylglycero)phosphate (BMP).

HY-172043

5-Fluoro PB-22 N-(2-fluoropentyl) isomer	Cannabinoid Receptor	Neurological Disease
5-Fluoro PB-22 N-(2-fluoropentyl) isomer is a derivative of cannabinoid.

HY-141877B

*MS4322 (isomer)* YS43-22 (isomer)	PROTACs Histone Methyltransferase	Cancer
MS4322 (YS43-22) isomer is an isomer of MS4322. MS4322 is a specific PRMT5 PROTAC degrader. MS4322 reduces the PRMT5 protein level with a DC₅₀ of 1.1 μM in MCF-7 cells. MS4322 inhibits the methyltransferase activity of PRMT5 with an IC₅₀ of 18 nM. MS4322 promotes ubiquitination and degradation of PRMT5. MS4322 can be used for the research of breast cancer, lung cancer, and hepatocellular cancer. (Pink: PRMT5 ligand (HY-173092); Blue: E3 ligase ligand HY-112078); Black: linker (HY-124780); E3+linker (HY-173093 )) .

HY-101704

Y1 receptor antagonist 1 H 409-22 (isomer)	Neurokinin Receptor	Cardiovascular Disease Neurological Disease
Y1 receptor antagonist 1 (H 409-22 isomer) (Example 4) is a neuropeptide Y1 receptor antagonist. Y1 receptor antagonist 1 can be used for the study of cardiovascular diseases, such as vasoconstriction .

HY-101704A

Y1 receptor antagonist 1 formic H 409-22 isomer formic	Neurokinin Receptor	Cardiovascular Disease Neurological Disease
Y1 receptor antagonist 1 (H 409-22 isomer) formic (Example 4) is a neuropeptide Y1 receptor antagonist. Y1 receptor antagonist 1 can be used for the study of cardiovascular diseases, such as vasoconstriction .

HY-W007978B

1,1'-Binaphthyl-2,2'-diamine 2,2'-Diamino-1,1'-dinaphthyl	Biochemical Assay Reagents	Others
1,1'-Binaphthyl-2,2'-diamine is the isomer of (S)-[1,1'-Binaphthalene]-2,2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W007978

(R)-[1,1'-Binaphthalene]-2,2'-diamine R-(-)-2,2-Diamino-1,1-binaphthyl	Biochemical Assay Reagents	Others
(R)-[1,1'-Binaphthalene]-2,2'-diamine is the isomer of (S)-[1,1'-Binaphthalene]-2,2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-111156

NW-1172 free base	Monoamine Oxidase	Neurological Disease
NW-1172 (free base) (compound 22b) is a 5-HT3 receptor antagonist with performance-enhancing activity in a delayed matching task in monkeys, with the (R) isomer producing more systematic improvements than the (S) isomer, a difference paralleled by the higher affinity of the (R) enantiomer for the 5-HT3 receptor.

HY-13631I

(1S,9R)-Exatecan mesylate (1S,9R)-DX8951f	ADC Payload Topoisomerase	Cancer
(1S,9R)-Exatecan mesylate ((1S,9R)-DX8951f) is an isomer of Exatecan mesylate (HY-13631A). Exatecan mesylate (DX8951f) is an inhibitor of DNA topoisomerase I with an IC50 of 2.2 μM (0.975 μg/mL) and can be used in cancer research .

HY-13631J

(1R,9R)-Exatecan mesylate (1R,9R)-DX8951f	ADC Payload Topoisomerase	Cancer
(1R,9R)-Exatecan mesylate((1R,9R)-DX8951f) is an isomer of Exatecan mesylate (HY-13631A). Exatecan mesylate (DX8951f) is an inhibitor of DNA topoisomerase I with an IC50 of 2.2 μM (0.975 μg/mL) and can be used in cancer research .

HY-12788A

(S)-PF-04449613	Phosphodiesterase (PDE)	Neurological Disease
(S)-PF-04449613 is the left-handed isomer of PF-04449613 (HY-12788). PF-04449613 is a selective PDE9A inhibitor with an IC₅₀ of 22 nM. PF-04449613 improves motor learning ability in a mouse model .

HY-18629A

(E/Z)-SU9516	Apoptosis CDK Autophagy	Cancer
(E/Z)-SU9516 is the isomer of SU9516 (HY-18629). SU9516 is a potent CDK2 inhibitor，with an IC₅₀ of 22 nM，and also shows inhibitory effects on CDK1 and CDK4，with IC₅₀s of 40，200 nM，respectively.

HY-W093104

(S)-(-)-2-Methylbutanol (S)-2-Methyl-1-butanol	Endogenous Metabolite	Others
(S)-(-)-2-Methylbutanol is a S-isomer of 2-Methylbutanol .

HY-W721259

2-Bromoamphetamine hydrochloride	Drug Isomer	Others
2-Bromoamphetamine hydrochloride is an isomer of 4-Bromoamphetamine. 4-Bromoamphetamine is a psychoactive substance .

HY-103641

(2R)-Octyl-α-hydroxyglutarate 2 Publications Verification (2R)-Octyl-2-HG	Others	Cancer
(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a modified form of D-isomer 2-Hydroxyglutarate.

HY-103641A

(2S)-Octyl-α-hydroxyglutarate 2 Publications Verification (2S)-Octyl-2-HG	Others	Cancer
(2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate.

HY-165116

1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE 18:0p/22:6-PE; C18(Plasm)-22:6-PE; PE(P-18:0/22:6)	Endogenous Metabolite	Others
1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE (18:0p/22:6-PE) is a lipid identified in rat brain tissue by mass spectrometry imaging with specific structural and distribution characteristics, and isomers of different fatty acid chains can be identified by improved methods.

HY-109167

Aramisulpride (R)-Amisulpride; (R)-Esamisulpride; (R)-DAN 2163	Dopamine Receptor 5-HT Receptor	Neurological Disease
Aramisulpride (R-(+)-Amisulpride) is the R-isomer of Amisulpride (HY-14545). Aramisulpride is a 5-HT₇ receptor antagonist with a K_i value of 22 nM. Aramisulpride is a D₂/D₃ receptor antagonist with a K_i value of 140 nM for D₂R and a K_i value of 13.9 nM for D₃R. Aramisulpride can be used in psychiatric research .

HY-128603

2-Hydroxyisobutyryl-CoA	Biochemical Assay Reagents	Metabolic Disease
2-Hydroxyisobutyryl-CoA is a hydroxy fatty acyl-CoA. 2-Hydroxyisobutyryl-CoA mutase forms the isomer (S)-3-hydroxybutyryl-CoA .

HY-134211

(Z)-2-Octenoic acid	Endogenous Metabolite	Others
Z-2-Octenoic acid is the Z-isomer of 2-Octenoic acid. trans-2-Octenoic acid is a metabolite of Mucor species.

HY-113381A

(R)-2-Hydroxybutanoic acid (R)-α-Hydroxybutyric acid	Drug Isomer	Metabolic Disease
(R)-2-Hydroxybutanoic acid is the isomer of 2-Hydroxybutyric acid (HY-113381), and can be used as an experimental control. 2-Hydroxybutyric acid (α-Hydroxybutyric acid ) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite .

HY-137516A

LC-2 epimer	PROTACs Ras	Cancer
LC-2 epimer is a differential isomer of LC-2. LC-2 is a mutation-selective PROTAC depressant for KRAS and contains a ligand for the von Hippel Lindau E3 ligase linked to the KRAS inhibitor MRTX849 .

HY-113381B

(R)-2-Hydroxybutanoic acid sodium (R)-α-Hydroxybutyric acid sodium	Endogenous Metabolite Drug Isomer	Others
(R)-2-Hydroxybutanoic acid ((R)-α-Hydroxybutyric acid) sodium is the R-isomer of 2-Hydroxybutyric acid (HY-113381), and can be used as an experimental control. 2-Hydroxybutyric acid is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite .

HY-70059A

(Rac)-LY341495	mGluR	Neurological Disease
(Rac)-LY341495 is the isomers of LY341495 (HY-70059) can be used as control compounds in experiments. LY341495 is a metabotropic glutamate receptor (mGluR) antagonist with IC₅₀s of 21 nM, 14 nM, 7.8 μM, 8.2 μM, 170 nM, 990 nM, 22 μM for mGlu2, mGlu3, mGlu1a, mGlu5a, mGlu8, mGlu7, and mGlu4 receptors, respectively .

HY-133016A

(R)-M8891	MetAP	Others
(R)-M8891 (compound R-9) is a less active isomer of M8891. M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor .

HY-15464D

(S)-Gossypol (acetic acid) 3 Publications Verification (S)-(+)-Gossypol acetic acid	Bcl-2 Family	Cancer
(S)-Gossypol is the isomer of a natural product Gossypol. (S)-Gossypol binds to the BH3-binding groove of Bcl-xL and *Bcl-2* proteins with high affinity.

HY-121582

(E)-SI-2 (E)-EPH 116	Drug Isomer	Cancer
(E)-SI-2 is an isomer of SI-2, an inhibitor of the steroid receptor coactivator SRC-3. SI-2 has anticancer activity and increases the number of cytotoxic immune cells in mice with breast cancer .

HY-123587A

(R)-PR-924	Apoptosis	Cancer
(R)-PR-924 is the isomer of PR-924 (HY-123587), and can be used as an experimental control. PR-924 is a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor with an IC₅₀ of 22 nM. PR-924 covalently modifies proteasomal N-terminal threonine active sites. PR-924 inhibits growth and triggers apoptosis in multiple myeloma (MM) cells. PR-924 has antitumor activities .

HY-103641R

(2R)-Octyl-α-hydroxyglutarate (Standard) (2R)-Octyl-2-HG (Standard)	Histone Demethylase Reference Standards Others	Cancer
(2R)-Octyl-α-hydroxyglutarate (Standard) is the analytical standard of (2R)-Octyl-α-hydroxyglutarate. This product is intended for research and analytical applications. (2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a modified form of D-isomer 2-Hydroxyglutarate.

HY-N7864

Osbond acid all-cis-4,7,10,13,16-Docosapentaenoic acid	Biochemical Assay Reagents	Others
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-171002

PAD2-IN-2	Protein Arginine Deiminase	Cancer
PAD2-IN-2 (cis-isomer of 1) is a protein arginine deiminase 2 (PAD2) inhibitor. PAD2-IN-2 possess an azobenzene photoswitch to optically control PAD activity. PAD2-IN-2 inhibits histone H3-citrullination .

HY-171002A

PAD2-IN-2 TFA	Protein Arginine Deiminase	Cancer
PAD2-IN-2 (cis-isomer of 1) TFA is a protein arginine deiminase 2 (PAD2) inhibitor. PAD2-IN-2 TFA possess an azobenzene photoswitch to optically control PAD activity. PAD2-IN-2 TFA inhibits histone H3-citrullination .

HY-103641AS1

(2R)-Octyl-α-hydroxyglutarate-d17 (2R)-Octyl-2-HG-d₁₇	Isotope-Labeled Compounds Others	Cancer
(2R)-Octyl-α-hydroxyglutarate-d₁₇ ((2R)-Octyl-2-HG-d₁₇) is deuterium labeled (2R)-Octyl-α-hydroxyglutarate (HY-103641). (2R)-Octyl-α-hydroxyglutarate is a modified form of S-isomer 2-Hydroxyglutarate .

HY-12940A

(S)-GLPG0974	Free Fatty Acid Receptor	Metabolic Disease
(S)-GLPG0974 is the isomer of GLPG0974 (HY-12940), and can be used as an experimental control. GLPG0974 is a *free fatty acid receptor-2* (FFA2/GPR43) antagonist with an IC₅₀** of 9 nM.

Cat. No.	Product Name	Type

HY-N7864

Osbond acid

all-cis-4,7,10,13,16-Docosapentaenoic acid

Cell Assay Reagents

Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-W776824

2-Phthalimidolactosamine,heptaacetate (mixture of isomers)

Carbohydrates

2-Phthalimidolactosamine,heptaacetate (mixture of isomers) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

Cat. No.	Product Name	Target	Research Area

HY-P5327

r8 Bid BH3	Bcl-2 Family	Others
r8 Bid BH3 is a biological active peptide. (The Bid BH3 is a pro-apoptotic member of the 'BH3-only' subset of BCL-2 family proteins that constitute a critical control point in apoptosis. r8BIDBH3 is lethal to human leukemia cell lines that expresse Bcl-2. The Bcl-2 antagonists may have the potential to be efficacious in cancer therapy. Poly-D-arginine (d-isomer as denoted by rrrrrrrr) is fused to the Bid BH3 peptide to facilitate cellular uptake of the peptide.)

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W087952

(R)-(-)-2-Butanol	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Drug Intermediate
(R)-(-)-2-Butanol is the isomer of 2-Butanol, which is found in the females of the white grub beetle, Dasylepida ishigakiensis, to attract males. (R)-(-)-2-Butanol is an intermediate of pharmaceutical synthesis by coupling .

HY-15464

(R)-(-)-Gossypol 2 Publications Verification AT-101; R-(-)-gossypol acetic acid	Malvaceae Structural Classification Classification of Application Fields Gossypium Source classification Phenols Plants Disease Research Fields Cancer	Bcl-2 Family Autophagy
(R)-(-)-Gossypol (AT-101) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to *Bcl-2, Mcl-1* and Bcl-xL proteins with K_is of 260±30 nM, 170±10 nM, and 480±40 nM, respectively.