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15-lipoxygenase-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Lipoxygenase (3) Apoptosis (1) Endogenous Metabolite (1) LOX-1 (1)
By Research Areas:	Cancer (1) Inflammation/Immunology (4) Neurological Disease (1)

5

Inhibitors & Agonists

2

Antibodies

Targets Recommended: Lipoxygenase 15-PGDH Enteropeptidase FLAP EHD Protein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

ThioLox	Lipoxygenase	Neurological Disease Inflammation/Immunology
ThioLox is a competitive 15-lipoxygenase-1 (15-LOX-1) inhibitor with a K_i of 3.30 μM. ThioLox shows anti-inflammatory and neuroprotective properties .

15-LOX-1 inhibitor 1	Lipoxygenase	Inflammation/Immunology
15-LOX-1 inhibitor 1 is a potent inhibitor of 15-LOX-1 (15-lipoxygenase-1) with an IC₅₀ value of 0.19 μM. 15-LOX-1 inhibitor 1 protects macrophages from lipopolysaccharide-induced cytotoxicity. 15-LOX-1 inhibitor 1 inhibits NO formation and lipid peroxidation .

4-MMPB	Lipoxygenase Apoptosis	Cancer
4-MMPB is a selective inhibitor of *15-lipoxygenase, with an IC₅₀* of 18 μM. 4-MMPB has IC₅₀s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate cancer .

14,15-Leukotriene D4 14,15-LTD4; Eoxin D4	Endogenous Metabolite	Inflammation/Immunology
14,15-Leukotriene D4 (14,15-LTD4) is a leukotriene that producted by eosinophils with Arachidonic acid (HY-109590), and through the 15-lipoxygenase-1 pathway .

15-LOX-1 inhibitor 2	LOX-1	Inflammation/Immunology
15-LOX-1 inhibitor 2 (Compound 5i) is an inhibitor of 15-lipoxygenase-1 (15-LOX-1) with an IC₅₀ of 1.7 μM. 15-LOX-1 inhibitor 2 inhibits the activity of 15-LOX-1 enzyme, reduces the production of lipid peroxides, thereby inhibiting lipid peroxidation and protecting cells from cell death induced by RSL3 (HY-100218A). 15-LOX-1 inhibitor 2 can be used in research on cell death mechanisms, oxidative stress-related diseases and other fields .

Cat. No.	Compare	Product Name	Application	Reactivity

	15 Lipoxygenase 1/ALOX15 Atibody (YA1091) LOG15; LOG15; Polyunsaturated fatty acid lipoxygenase ALOX15; Polyunsaturated fatty acid lipoxygenase ALOX15	IHC-P	Human
	15 Lipoxygenase 1/ALOX15 Antibody (YA1091) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to 15 Lipoxygenase 1/ALOX15 .

	15 Lipoxygenase 1/ALOX15 Atibody (YA1309) LOG15	IHC-P, ICC/IF, FC	Human
	15 Lipoxygenase 1/ALOX15 Antibody (YA1309) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to 15 Lipoxygenase 1/ALOX15.

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