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Results for "

α-Amylase inhibition

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

5

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N1495
    Maltopentaose

    Maltopentose

    		 Amylases Others
    Maltopentaose is the shortest chain oligosaccharide. Maltopentaose is a substrate for α-amylases. Maltopentaose can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of α-lactalbumin. Maltopentaose is used to study the inhibition kinetics of human pancreatic α-amylase by dehydrodieugenol B .
    Maltopentaose
  • HY-N8161
    Kaempferol-3,7-di-O-β-glucoside

    Kaempferol 3,7-diglucoside

    		 Glycosidase Cholinesterase (ChE) Neurological Disease
    Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside), a flavonol, possesses enzyme inhibition property towards α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3,7-di-O-β-glucoside protects differentiating neuronal cells, SH-SY5Y from Amyloid β peptide-induced injury. Kaempferol-3,7-di-O-β-glucoside has the potential for Alzheimer's research .
    Kaempferol-3,7-di-O-β-glucoside
  • HY-178363
    α-Amylase-IN-13

    		Amylases Metabolic Disease Endocrinology
    α-Amylase-IN-13 is an orally active, selective, brain-penetrant α-amylase inhibitor (IC50 = 0.71 μM). α-Amylase-IN-13 inhibits α-amylase through a mixed type of inhibition mechanism. α-Amylase-IN-13 leads to a significant reduction in blood glucose level in diabetic rats. α-Amylase-IN-13 causes significant histopathological improvements in the kidney, liver, and pancreas. α-Amylase-IN-13 can be used for the study of diabetic complications .
    α-Amylase-IN-13
  • HY-168495
    α-Amylase-IN-12

    		Amylases Glycosidase Metabolic Disease
    α-Amylase-IN-12 (Compound 5e) is an α-amylase inhibitor (IC50: 0.15 mM) with a mixed inhibition. α-Amylase-IN-12 has an IC50 of 9.40 mM against α-glucosidase. α-Amylase-IN-12 promotes glucose uptake in yeast cells and exhibits significant antiglycation activity at high concentrations. α-Amylase-IN-12 can be used for the research of diabetes .
    α-Amylase-IN-12
  • HY-N11844
    Quercetin 3-(6″-caffeoylsophoroside)

    		Amylases Metabolic Disease
    Quercetin 3-(6″-caffeoylsophoroside) is an orally active α-amylase inhibitor, with an IC50 of 73.66 μg/mL. Quercetin 3-(6″-caffeoylsophoroside) presents in thehydro-methanolic extract of Cardamine hirsuta Linn. Quercetin 3-(6″-caffeoylsophoroside) shows the antidiabetic activities by oxidative stress reduction and α-amylase inhibition. Quercetin 3-(6″-caffeoylsophoroside) can be used for diabetes mellitus research .
    Quercetin 3-(6″-caffeoylsophoroside)
  • HY-N10360
    Ellipyrone A

    		Dipeptidyl Peptidase Metabolic Disease
    Ellipyrone A, a γ-pyrone enclosed macrocyclic poyketide, shows inhibition potential against dipeptidyl peptidase-4 (IC50=0.35 mM). Ellipyrone A also has anti-carbolytic property against α-glucosidase (IC50=0.74 mM) and α-amylase (IC50=0.59 mM) .
    Ellipyrone A
  • HY-N9916
    8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside

    		Amylases Metabolic Disease
    8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside (Compound 3) is natural product that can be isolated from Bidens bipinnata. 8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside shows 22% inhibition against α-amylase at 0.556 mg/mL .
    8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside
  • HY-149973
    α-Amylase-IN-4

    		Amylases Metabolic Disease
    α-Amylase-IN-4 (Compd 10y) show maximum inhibition of amylase activity with IC50 value 17.83 ± 0.14 μg/mL .
    α-Amylase-IN-4
  • HY-146752
    α-Amylase-IN-1

    		Amylases Others
    α-Amylase-IN-1 is a potent α-amylase inhibitor with an IC50 of 4.46 μM .
    α-Amylase-IN-1

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