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Pnkp

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P71620
    PNKP Protein, Human (His-SUMO)

    2''(3'')-polynucleotidase; 2'(3')-polynucleotidase; Bifunctional polynucleotide phosphatase/kinase; DEM 1; DEM1; Polynucleotide kinase-3''-phosphatase

    		 Human E. coli
    PNKP protein plays a key role in DNA damage repair through NHEJ and BER pathways. Its dual catalytic activity includes removal of the 3'-phosphate group from the DNA backbone and phosphorylation of the 5'-hydroxyl group, ensuring compatibility of DNA ends during extension and ligation. PNKP Protein, Human (His-SUMO) is the recombinant human-derived PNKP protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

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