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Aph1a

" in MedChemExpress (MCE) Product Catalog:
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  • HY-P702211

    Gamma-secretase subunit Aph-1a; Aph-1alpha; Presenilin-stabilization factor

    Human E. coli Cell-free
    The APH1A protein is a noncatalytic subunit of the γ-secretase complex and is essential for the assembly of this endoprotease. The γ-secretase complex, including presenilin homodimer, nicastrin, APH1A, and PSENEN/PEN2, catalyzes the cleavage of intramembrane proteins such as Notch and APP. APH1A Protein, Human (Cell-Free, His, SUMO) is the recombinant human-derived APH1A protein, expressed by E. coli Cell-free , with N-6*His, N-SUMO labeled tag.

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