2. Anti-infection
  3. SARS-CoV Virus Protease
  4. SARS-CoV-2 PLpro-IN-2

SARS-CoV-2 PLpro-IN-2 (Compound 12) is a highly selective SARS-CoV-2 papain-like protease (PLpro) inhibitor of (IC50=0.06 μM). SARS-CoV-2 PLpro-IN-2 inhibits viral replication and immune evasion. SARS-CoV-2 PLpro-IN-2 exhibits antiviral efficacy in HeLa-ACE2 cells (EC50=2.9 μM). SARS-CoV-2 PLpro-IN-2 is promising for research of COVID-19.

For research use only. We do not sell to patients.

SARS-CoV-2 PLpro-IN-2

SARS-CoV-2 PLpro-IN-2 Chemical Structure

CAS No. : 1581755-42-1

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SARS-CoV-2 PLpro-IN-2 Related Antibodies

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Description

SARS-CoV-2 PLpro-IN-2 (Compound 12) is a highly selective SARS-CoV-2 papain-like protease (PLpro) inhibitor of (IC50=0.06 μM). SARS-CoV-2 PLpro-IN-2 inhibits viral replication and immune evasion. SARS-CoV-2 PLpro-IN-2 exhibits antiviral efficacy in HeLa-ACE2 cells (EC50=2.9 μM). SARS-CoV-2 PLpro-IN-2 is promising for research of COVID-19[1].

Molecular Weight

406.95

Formula

C25H27ClN2O
CAS No.
SMILES

C[C@@H](N1CCC(C(NCC2=CC=C(Cl)C=C2)=O)CC1)C3=CC=CC4=CC=CC=C43
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Purity & Documentation
References
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SARS-CoV-2 PLpro-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARS-CoV-2 PLpro-IN-21581755-42-1SARS-CoVVirus ProteaseSARS coronavirusPLproviral replicationimmune evasionantiviral efficacyInhibitorinhibitorinhibit

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