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  4. VEGFR-2 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi)

VEGFR-2 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi)

Cat. No.: HY-P703862
Handling Instructions Technical Support

VEGFR-2 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi) is the recombinant cynomolgus-derived VEGFR-2 protein, expressed by HEK293, with C-His & Avi tag.

For research use only. We do not sell to patients.

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Description

VEGFR-2 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi) is the recombinant cynomolgus-derived VEGFR-2 protein, expressed by HEK293, with C-His & Avi tag.
Background

VEGFR-2 protein mediates vascular endothelial growth factor (VEGF)-induced endothelial proliferation, survival, migration, tubular morphogenesis, and sprouting, and plays a key role in angiogenesis and vasculogenesis[1][3].
The signal of VEGFR-2 protein is a survival mechanism in hippocampal neurons, which can prevent mitochondrial dysfunction and oxidative stress[2].
VEGFR-2 Protein is highly expressed in the microvessels of diabetes and can be used as a biomarker for early diagnosis of diabetes retinopathy (DR) [4].
VEGFR-2 protein mediates hydrogen sulfide (H2S)-induced dilation of rat basilar artery[5].
Species

Cynomolgus
Source

HEK293
Tag

C-His;Avi
Accession

EHH53800.1 (S22-E764)
Gene ID

/
Protein Length

Partial
Synonyms
kinase insert domain receptor
Predicted Molecular Mass
86.6 kDa
Molecular Weight

Approximately 131.6 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

VEGFR-2 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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