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  3. SPIN4 Protein, Human (His)

The SPIN4 protein exhibits H3K4me3 binding activity, demonstrating affinity for lysine 4 trimethylated histone H3. This unique combination suggests a role in recognizing specific chromatin modifications, potentially regulating gene expression or chromatin dynamics. SPIN4 Protein, Human (His) is the recombinant human-derived SPIN4 protein, expressed by E. coli , with N-6*His labeled tag.

For research use only. We do not sell to patients.

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Description

The SPIN4 protein exhibits H3K4me3 binding activity, demonstrating affinity for lysine 4 trimethylated histone H3. This unique combination suggests a role in recognizing specific chromatin modifications, potentially regulating gene expression or chromatin dynamics. SPIN4 Protein, Human (His) is the recombinant human-derived SPIN4 protein, expressed by E. coli , with N-6*His labeled tag.

Background

SPIN4 protein showcases H3K4me3-binding activity, indicating its affinity for histone H3 trimethylated at lysine 4. This unique binding ability suggests a potential role for SPIN4 in recognizing specific chromatin modifications, implicating it in the regulation of gene expression or chromatin dynamics. Additionally, SPIN4 interacts with C11orf84/SPINDOC, indicating a potential partnership or functional association with this interacting protein. These molecular interactions underscore the intricate involvement of SPIN4 in epigenetic processes and protein-protein interactions, hinting at its potential significance in cellular regulation and chromatin-related functions.

Species

Human

Source

E. coli

Tag

N-6*His

Accession

Q56A73 (S2-P249)

Gene ID

139886

Molecular Construction
N-term
6*His
SPIN4 (S2-P249)
Accession # Q56A73
C-term
Protein Length

Partial

Synonyms
SPIN4; Spindlin-4
Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

SPIN4 Protein, Human (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
SPIN4 Protein, Human (His)
Cat. No.:
HY-P701840
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