SLC35A2 Protein, Human (Sf9, His, MBP, FLAG)

SLC35A2 is a key transmembrane protein that acts as an antiporter to transport uridine diphosphate galactose (UDP-galactose) into the Golgi apparatus. The process involves the exchange of UDP-galactose with UMP and exhibits versatility through exchange with AMP and CMP. SLC35A2 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC35A2 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag.

SLC35A2, a pivotal transmembrane protein, operates as an antiporter facilitating the transportation of uridine diphosphate galactose (UDP-galactose) from the cytosol into the Golgi apparatus. This dynamic process involves the exchange of UDP-galactose for UMP and demonstrates versatility by also accommodating the exchange of UDP-galactose for AMP and CMP. Furthermore, SLC35A2 exhibits the ability to transport other nucleotide sugars, including UDP-N-acetylgalactosamine (UDP-GalNAc). Its role as a provider of UDP-galactose to galactosyltransferases within the Golgi apparatus is particularly crucial for the synthesis of globotriaosylceramide/globoside (Gb3Cer) from lactosylceramide, underscoring its significance in glycosphingolipid biosynthesis.

Human

Sf9 insect cells

N-MBP;C-Flag;N-8*His

P78381 (A2-S396)

7355

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.