PTK7 Protein, Rat (HEK293, Fc)

The PTK7 protein is predicted to mediate cell adhesion molecule binding and play critical roles in a variety of cellular processes, including actin cytoskeleton reorganization and regulation of the canonical Wnt signaling pathway. It affects animal organ development, axis elongation, and epithelial morphogenesis. PTK7 Protein, Rat (HEK293, Fc) is the recombinant rat-derived PTK7 protein, expressed by HEK293 , with C-hFc labeled tag.

The PTK7 protein is anticipated to play a crucial role in mediating cell adhesion molecule binding activity. Its involvement is predicted in diverse cellular processes, including the reorganization of the actin cytoskeleton, cellular response to retinoic acid, and positive regulation of the canonical Wnt signaling pathway. Additionally, it is expected to exert influence upstream of or within essential processes such as animal organ development, axis elongation, and epithelial morphogenesis. The predicted subcellular localization of PTK7 is in the membrane, with anticipated activity at cell-cell junctions and the plasma membrane. Notably, PTK7 demonstrates biased expression, with elevated levels observed in the lung (RPKM 114.4), uterus (RPKM 97.1), and eight other tissues, indicating its potential significance in these physiological contexts. [information derived from Alliance of Genome Resources, April 2022]

Rat

HEK293

C-hFc

NP_001382670.1 (A23-Q695)

301242  [NCBI]

120-140 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<0.1 EU/μg, determined by LAL method.