2. Recombinant Proteins
  3. Viral Proteins
  4. p24 Protein, HIV-1 (His)

p24 Protein, HIV-1 (His) is the recombinant virus-derived p24 , HIV-1 protein, expressed by E. coli, with C-6*His tag.

For research use only. We do not sell to patients.

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Top Publications Citing Use of Products

  • Biological Activity

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Description

p24 Protein, HIV-1 (His) is the recombinant virus-derived p24 , HIV-1 protein, expressed by E. coli, with C-6*His tag.
Background

HIV-1 p24, the core capsid protein of HIV-1, collaborates with Gag-Pol polyprotein to mediate essential steps in virion assembly. Its functions include: binding the plasma membrane, facilitating protein-protein interactions for spherical particle formation, recruiting viral Env proteins, and packaging genomic RNA via direct interaction with the Psi RNA packaging sequence. by similar: p24 belongs to the Gag protein family and serves as a core structural component for viral assembly.
Species

Virus
Source

E. coli
Tag

C-6*His
Accession

P12493 (M142-G355)
Gene ID

/
Protein Length

Partial
Synonyms
p24
Predicted Molecular Mass
24.6 kDa
Molecular Weight

Approximately 25 kDa,based on SDS-PAGE under reducing conditions.
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

p24 Protein, HIV-1 (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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p24 Protein, HIV-1 (His)
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