1. Recombinant Proteins
  2. Cytokines and Growth Factors
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  4. OSM Receptor
  5. OSMR beta Protein, Cynomolgus (HEK293, His)

OSMR beta protein is a type I cytokine receptor in the type 2 subfamily and is critical in cell signaling and immune responses. OSMR beta serves as a receptor for oncostatin M, a cytokine that plays a role in inflammation, cell growth, and differentiation, and is critical for downstream signaling and regulation of cell function. OSMR beta Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived OSMR beta protein, expressed by HEK293 , with C-His labeled tag.

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Description

OSMR beta protein is a type I cytokine receptor in the type 2 subfamily and is critical in cell signaling and immune responses. OSMR beta serves as a receptor for oncostatin M, a cytokine that plays a role in inflammation, cell growth, and differentiation, and is critical for downstream signaling and regulation of cell function. OSMR beta Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived OSMR beta protein, expressed by HEK293 , with C-His labeled tag.

Background

The OSMR beta protein belongs to the type I cytokine receptor family, specifically the type 2 subfamily. This protein plays a significant role in cellular signaling and immune responses. It acts as a receptor for oncostatin M, a cytokine involved in various biological processes such as inflammation, cell growth, and differentiation. The OSMR beta protein is essential for the activation of downstream signaling pathways and the regulation of cellular functions. Understanding the function and regulation of OSMR beta protein can provide valuable insights into the development of therapeutic strategies for diseases involving dysregulation of cytokine signaling or immune responses.

Species

Cynomolgus

Source

HEK293

Tag

C-8*His

Accession

A0A2K5UFW5 (E28-S737)

Gene ID

102135082

Molecular Construction
N-term
OSMR beta (E28-S737)
Accession # A0A2K5UFW5
8*His
C-term
Protein Length

Extracellular Domain

Synonyms
IL-31R subunit beta; IL-31R-beta; IL-31RB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1 ; IL-31R subunit β; IL-31R-β; OSMR β
Predicted Molecular Mass
82 kDa
Molecular Weight

Approximately 110-130 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

OSMR beta Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
OSMR beta Protein, Cynomolgus (HEK293, His)
Cat. No.:
HY-P700806
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