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  4. NUP50 Protein, Human (His, Strep)

NUP50 Protein, Human (His, Strep) is the recombinant human-derived NUP50, expressed by E. coli , with Strep, His labeled tag. ,

For research use only. We do not sell to patients.

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Description

NUP50 Protein, Human (His, Strep) is the recombinant human-derived NUP50, expressed by E. coli , with Strep, His labeled tag. ,
Background

NUP50 is a component of the nuclear pore complex that plays a direct role in nuclear protein import. It actively displaces nuclear localization signals (NLSs) from importin-alpha and facilitates the disassembly of the importin-alpha:beta-cargo complex, promoting importin recycling. Additionally, NUP50 interacts with cell cycle regulatory proteins, including CDKN1B (by similar), and this interaction is required for proper intracellular transport and degradation of CDKN1B (by similar).
Species

Human
Source

E. coli
Tag

Strep;His
Accession

Q9UKX7-1 (E351-A468)
Gene ID

10762
Protein Length

Partial
Synonyms
NPAP60L
Predicted Molecular Mass
16.5 kDa
Purity

Greater than 80% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

NUP50 Protein, Human (His, Strep) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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NUP50 Protein, Human (His, Strep)
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