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  4. NR6A1 Protein, Human

NR6A1 Protein, Human is the recombinant human-derived NR6A1, expressed by E. coli , with tag Free labeled tag. ,

For research use only. We do not sell to patients.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

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100 μg   Get quote  

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Top Publications Citing Use of Products

  • Biological Activity

  • Technical Parameters

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Description

NR6A1 Protein, Human is the recombinant human-derived NR6A1, expressed by E. coli , with tag Free labeled tag. ,
Background

NR6A1 is an orphan nuclear receptor that binds to a response element containing the sequence 5'-TCAAGGTCA-3'. It acts as a regulator of embryonic stem cell pluripotency by mediating repression of POU5F1/OCT4: binding to the DR0 element within the POU5F1/OCT4 promoter and inhibiting POU5F1/OCT4 expression during embryonic stem cell differentiation. Additionally, it is involved in the regulation of gene expression in germ cell development during gametogenesis (by similar).
Species

Human
Source

E. coli
Tag

Tag Free
Accession

Q15406 (E2-E480)
Gene ID

2649
Protein Length

Partial
Synonyms
GCNF
Predicted Molecular Mass
54.4 kDa
Purity

Greater than 85% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

NR6A1 Protein, Human Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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NR6A1 Protein, Human
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HY-P703134
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